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Academic Articles & Research Papers
Showing 20 of 1,492 academic articles
Qinghua Luo, Xintan Dong, Zhaxi Zerang, Yujiao Chen et al. • Cell Reports
(2026)
Summary: The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2026.117733
Maral Rahimzadeh, Majid Sadeghizadeh, Farhood Najafi, Seyed Shahriar Arab et al. • Materials Research Express
(2020)
During the last few decades, extensive studies have been conducted to elucidate the anti-cancer effects of curcumin. Despite promising results indicating curcumin could impede cancer cells ability thrive and proliferation, clinical applicat...
DOAJ
Open Access (DOAJ)
DOI: 10.1088/2053-1591/ab770f
Khushboo Singh, Roon Banerjee, Chandrakanta Potdar, Anisha Shaw et al. • Cells
(2026)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are among the most common genetic causes of Parkinson’s disease (PD), yet substantial heterogeneity exists among pathogenic variants. How mutations in distinct functional domains of LRRK2 di...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells15040342
Ligia Soares Lima, Jessyca Sousa de Brito, Marcelo Ribeiro-Alves, Karen Salve Coutinho-Wolino et al. • Foods
(2025)
Jaboticaba (Plinia cauliflora), a Brazilian native fruit rich in bioactive compounds, exhibits potent anti-inflammatory and antioxidant properties. This pilot study evaluated the effects of jaboticaba peel supplementation on inflammatory an...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/foods14234030
Natsuko Kitajima, Takahisa Nakajo, Takeshi Katayoshi, Kentaro Tsuji-Naito • Biochemistry and Biophysics Reports
(2023)
Sebocytes express Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs), which participate in the innate immune response of the skin. Although the roles of TLRs and NLR family pyrin domain-cont...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2023.101561
Li Rong, Haiyu Li, Zhaodong Li, Jing Ouyang et al. • Frontiers in Medicine
(2020)
Background and Objective: Chemotherapy and radiotherapy are effective treatment options for cervical cancer (CC), but their efficacy is limited by short survival rate of about 5 years particularly for advance stage CC. Bioinformatics analys...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmed.2020.608441
Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine
(2024)
Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12967-024-05257-w
Irandi Putra Pratomo, Dimas R. Noor, Kusmardi Kusmardi, Andriansjah Rukmana et al. • International Journal of Inflammation
(2021)
Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a ...
DOAJ
Open Access (DOAJ)
DOI: 10.1155/2021/1653392
Xhulio Dhori, Silvia Gioiosa, Stefania Gonfloni • Scientific Data
(2024)
Abstract Granulosa cells (GCs) play crucial roles in oocyte maturation. Through gap junctions and extracellular vesicles, they mediate the exchange of molecules such as microRNAs and messenger RNAs. Different ovarian cell types exhibit uniq...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41597-024-03715-0
Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology
(2022)
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb44050142
Suhel Tamboli, Sanjay Singh, Dimitry Topolnik, Mohamed El Amine Barkat et al. • Cell Reports
(2024)
Summary: In the CA1 hippocampus, vasoactive intestinal polypeptide-expressing interneurons (VIP-INs) play a prominent role in disinhibitory circuit motifs. However, the specific behavioral conditions that lead to circuit disinhibition remai...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2024.114115
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ
(2020)
Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...
DOAJ
Open Access (DOAJ)
DOI: 10.7717/peerj.9796
Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy
(2018)
Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13287-018-0807-3
K. B. Sumena, N. S. Sunilkumar, K. M. Lucy, S. Maya et al. • Journal of Veterinary and Animal Sciences
(2019)
Present study was conducted with the aim to understand the morphological features
of skull of barred jungle owlet.The head of the owletwascollected from the specimen brought for post-mortem, processed and morphological studies were conduct...
DOAJ
Open Access (DOAJ)
Sarah E. Brock, Dariia Yehorova, Brycelyn M. Boardman • Results in Chemistry
(2022)
Four novel small molecule acceptors (SMA) with fluorene-based cores were synthesized with terminal phenyl, thienyl, and furyl malononitrile groups in good yields. The products were obtained from a two-step reaction of 2,2′-(9,9-dioctyl-9H-f...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.rechem.2022.100320
Keisuke Hitachi, Masahiko Honda, Kunihiro Tsuchida • Cells
(2022)
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condit...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells11152291
Alireza Azarberahman, Mahmoodreza Mohammadnejadi Modi • Journal of Business and Socio-Economic Development
(2025)
PurposeThis research examines the structure of financial markets by integrating game theory and fuzzy logic. The objective is to develop a differential game model that analyzes competition among financial firms within a specific industry.De...
DOAJ
Open Access (DOAJ)
DOI: 10.1108/JBSED-03-2024-0030
Wonseok Yang • Applied Sciences
(2021)
This study presents a method to predict the flow velocity in a fluid-conveying pipe using vibration signals from the pipe surface. The flexural vibration of a fluid pipe is investigated through wave propagation. The wavenumbers and mode sha...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/app11135779
Deyu Jiang, Miao Luo, Changxi Liu, Yashuo Zhang et al. • Virtual and Physical Prototyping
(2025)
In this study, a Ti1.5Nb1Ta0.5Zr1Mo0.5 (TNTZM) high-entropy alloy was fabricated using laser powder bed fusion (LPBF). By integrating 63 sets of parameter trials with machine learning (ML) models, an optimised process window was identified,...
DOAJ
Open Access (DOAJ)
DOI: 10.1080/17452759.2025.2524524