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The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

Katja Niesel, Michael Schulz, Julian Anthes, Tijna Alekseeva et al. • EMBO Molecular Medicine (2021)

Abstract The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes. Desp...

DOAJ Open Access (DOAJ) DOI: 10.15252/emmm.202013412

Causal relationship between genetic-predicted uric acid and cervical cancer risk: evidence for nutritional intervention on cervical cancer prevention

Chunge Cao, Dajun Cai, Hao Liu, Xia Zhang et al. • Frontiers in Nutrition (2024)

IntroductionThe relationship between serum uric acid (SUA) and cervical cancer is inconclusive. This study aims to investigate the causal relationship between SUA levels and cervical cancer incidence, and to evaluate the potential role of n...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2024.1464046

Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles

Bettina Mannerström, Roman Kornilov, Ahmed G. Abu-Shahba, Iftekhar M. Chowdhury et al. • Epigenetics (2019)

Extracellular vesicles (EVs) are central to intercellular communication and play an important role in cancer progression and development. Osteosarcoma (OS) is an aggressive bone tumour, characterized by the presence of malignant mesenchymal...

DOAJ Open Access (DOAJ) DOI: 10.1080/15592294.2019.1585177

Concepts of Genetics

William S. Klug, Michael R. Cummings • Own your potential (DEAKIN) (1983)

Part 1 Heredity and the phenotype: cell division - mitosis and meosis Mendalian genetics modification of Mendelian ratios linkage and chromosome mapping in eukaryotes recombination and mapping in bacteria and bacteriophages extensions of ge...

OPENALEX

Health claims about cannabidiol (CBD) at the point-of-sale in three U.S. states with disparate cannabis policies

Kimberly G. Wagoner, Olivia E. Horton, Cynthia K. Suerken, E. Alfonso Romero-Sandoval et al. • Preventive Medicine Reports (2026)

Objectives: We assessed point-of-sale advertising for CBD in three states with different cannabis laws (i.e., medical/recreational use; medical only; CBD/low THC) to determine if CBD is marketed in ways that are prohibited by the U.S. Food ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pmedr.2026.103472

Acupuncture versus sham acupuncture and usual care for Antiandrogen-Induced hot fLashes in prostate cancer (AVAIL): study protocol for a randomized clinical trial

Zongshi Qin, Zhiwei Zang, Jianyong Yu, Jianqin Lv et al. • BMC Complementary Medicine and Therapies (2023)

Abstract Background Hot flashes are the common and debilitating symptom among prostate cancer (PCa) patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that pharmacolog...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12906-023-04218-y

Getting involved: Uganda cancer society´s efforts to build strategic partnerships for tobacco tax increments and strong tobacco industry monitoring

Evelyn Angiji, Paul Ebusu • Tobacco Induced Diseases (2018)

Background and challenges to implementation Uganda Cancer Society's (UCS) purpose is to coordinate civil society efforts for a systematic contribution towards effective cancer control in Uganda. UCS is moving towards fully integrating tobac...

DOAJ Open Access (DOAJ) DOI: 10.18332/tid/84466

Toward optimal implementation of cancer prevention and control programs in public health: a study protocol on mis-implementation

Margaret Padek, Peg Allen, Paul C. Erwin, Melissa Franco et al. • Implementation Science (2018)

Abstract Background Much of the cancer burden in the USA is preventable, through application of existing knowledge. State-level funders and public health practitioners are in ideal positions to affect programs and policies related to cancer...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13012-018-0742-9

Implementing self-collection for primary human papillomavirus testing: Perspectives on implications for federally qualified health center patient populations

Amanda Le, Liisa S. Smith, Stephanie B. Wheeler, Kara Giannone et al. • Women's Health (2025)

Background: Primary testing for high-risk human papillomavirus (HPV) via self-collection can increase cervical cancer screening rates. In the United States, federally qualified health center (FQHC) patients often have low incomes, lack heal...

DOAJ Open Access (DOAJ) DOI: 10.1177/17455057251362581

Lost to follow up?: A qualitative study of why some patients do not pursue lung cancer screening

Ilana B. Richman, Taara V. Prasad, Cary P. Gross • Preventive Medicine Reports (2022)

Although national guidelines recommend lung cancer screening for adults at high risk, only a small proportion of eligible adults in the US have been screened. The goal of this study was to understand barriers to screening among a specific b...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pmedr.2022.101909

Communicatively Constructing the Bright and Dark Sides of Hope: Family Caregivers’ Experiences during End of Life Cancer Care

Jody Koenig Kellas, Katherine M. Castle, Alexis Johnson, Marlene Z. Cohen • Behavioral Sciences (2017)

(1) Background: The communication of hope is complicated, particularly for family caregivers in the context of cancer who struggle to maintain hope for themselves and their loved ones in the face of terminality. In order to understand these...

DOAJ Open Access (DOAJ) DOI: 10.3390/bs7020033

CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression

Wei Yan, Guo-hui Xiao, Li-juan Wang, Yan Zhou et al. • Journal of Translational Medicine (2025)

Abstract Background The stiffness of the matrix is closely related to the progression of hepatocellular carcinoma (HCC). Although direct targeting of stromal rigidity in HCC remains a clinical challenge, cancer-associated fibroblasts (CAFs)...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-025-06325-5

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T. Malivanova, E. Skoromyslova, N. Mazurenko • EJC Supplements (2015)

Tumor necrosis factor alpha (TNF) is a multifunctional cytokine, which possesses various biologic functions depending on the type of the cells and the physiological context. TNF is synthesized by immune cells as well as malignant cells. Acc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejcsup.2015.08.063

Evaluating the diagnostic value and prospects of genomic and mutational sequencing in malignant transformation of oral leukoplakia

Jian Yuan, Yuhan Zhu, Zirui Wang, Zhongjing Lv et al. • Journal of Dental Sciences (2025)

Genomic and mutational sequencing in malignant transformation of oral leukoplakia (OLK) has emergingly gained momentum. In this short communication, we identified 5 retrospective follow-up studies and 5 cross-section comparative studies on ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jds.2025.07.016

Extracellular vesicles: A dive into their role in the tumor microenvironment and cancer progression

Kassandra Lopez, Seigmund Wai Tsuen Lai, Edwin De Jesus Lopez Gonzalez, Raúl G. Dávila et al. • Frontiers in Cell and Developmental Biology (2023)

Extracellular vesicles (EVs) encompass a diverse set of membrane-derived particles released from cells and are found in numerous biological matrices and the extracellular space. Specific classes of EVs include apoptotic bodies, exosomes, an...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcell.2023.1154576

Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway

Yogesh Goyal, Thomas J. Levario, Henry H. Mattingly, Susan Holmes et al. • Disease Models & Mechanisms (2017)

The Ras pathway patterns the poles of the Drosophila embryo by downregulating the levels and activity of a DNA-binding transcriptional repressor Capicua (Cic). We demonstrate that the spatiotemporal pattern of Cic during this signaling even...

DOAJ Open Access (DOAJ) DOI: 10.1242/dmm.030163

Relationship between Sn elemental background values and regional longevity levels-Data from Yunnan, China.

Shuangshuang Zhu, Jiaxue Wang, Xin Zhou, Min Lai et al. • PLoS ONE (2025)

The relationship between the geographic environment and human health has been a long-standing focus of scientific inquiry. Sn as an essential trace element for the human body, play vital roles in individual health and may influence longevit...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0332369