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Changes in daily living dependency and incident depressive symptoms among older individuals: findings from four prospective cohort studies

Hongwei Liu, Juxiang Yang, Gang Song, Minheng Zhang et al. • BMJ Mental Health (2025)

Background With rapid population ageing, depressive symptoms in older adults have become a pressing public health concern. While functional dependency is a known risk factor, the impact of changes in dependency over time remains unclear.Obj...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjment-2025-301749

Risk Profiles for Falls among Older Adults: New Directions for Prevention

William A. Satariano, Constance Wang, Melissa E. Kealey, Elaine Kurtovich et al. • Frontiers in Public Health (2017)

ObjectiveTo address whether neighborhood factors, together with older adults’ levels of health and functioning, suggest new combinations of risk factors for falls and new directions for prevention. To explore the utility of Grade-of-Members...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2017.00142

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus (2025)

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100171

Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits

Mateus H. Gouveia, Amy R. Bentley, Hampton Leonard, Karlijn A. C. Meeks et al. • Scientific Reports (2021)

Abstract Genome-wide association studies (GWAS) have identified thousands of genetic loci associated with cross-sectional blood pressure (BP) traits; however, GWAS based on longitudinal BP have been underexplored. We performed ethnic-specif...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-83450-3

Broca’s biases in modern aphasiology

Silvia Martínez-Ferreiro, Monica I. Norvik, Monica I. Norvik • Frontiers in Human Neuroscience (2026)

Broca’s description of aphemia signals the emergence of aphasiology as a discipline. It also marks the beginning of a long tradition of studies of right-handed patients (“Nous parlons avec l’hémisphère gauche”) with lesions in the inferior ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnhum.2026.1783073

<i>Sechium edule</i> var. <i>nigrum spinosum</i> (Chayote) Increases the mRNA Expression of Genes Encoding Sirtuins in Older Adults with Type 2 Diabetes Mellitus

Graciela Gavia-García, David Hernández-Álvarez, Taide Laurita Arista-Ugalde, Itzen Aguiñiga-Sánchez et al. • Molecules (2026)

Consumption of Sechium edule var. nigrum spinosum has antioxidant and hypoglycemic effects. Regarding the former, certain signaling pathways that influence these effects have already been proposed; however, the underlying molecular mechanis...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules31071182

Multimodel GCM-RCM Ensemble-Based Projections of Temperature and Precipitation over West Africa for the Early 21st Century

I. Diallo, M. B. Sylla, F. Giorgi, A. T. Gaye et al. • International Journal of Geophysics (2012)

Reliable climate change scenarios are critical for West Africa, whose economy relies mostly on agriculture and, in this regard, multimodel ensembles are believed to provide the most robust climate change information. Toward this end, we ana...

DOAJ Open Access (DOAJ) DOI: 10.1155/2012/972896

Effects of match period and playing position on the individual and collective dynamics in professional soccer: a case study

Gibson Moreira Praça, André Gustavo Pereira de Andrade, Sarah da Glória Teles Bredt, Pedro Emilio Drumond Moreira et al. • Revista Brasileira de Cineantropometria e Desempenho Humano (2020)

This study aimed to compare the width, the length, the length per width ratio, and the stretch index between the first and the second halves in official soccer matches, and to compare the spatial exploration index between players from diffe...

DOAJ Open Access (DOAJ)

High-quality read-based phasing of cystic fibrosis cohort informs genetic understanding of disease modification

Scott Mastromatteo, Angela Chen, Jiafen Gong, Fan Lin et al. • HGG Advances (2023)

Summary: Phasing of heterozygous alleles is critical for interpretation of cis-effects of disease-relevant variation. We sequenced 477 individuals with cystic fibrosis (CF) using linked-read sequencing, which display an average phase block ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.xhgg.2022.100156

Divergent biological consequences of APOE isoforms across industrialized and non-industrial environments.

Marina M Watowich, Rachel M Petersen, Layla Brassington, Audrey M Arner et al. • PLoS Genetics (2026)

The apolipoprotein ε4 (APOE ε4) isoform directly alters cholesterol and immune biology and is associated with an increased risk of neurodegenerative and cardiometabolic disease in industrialized settings; nevertheless, APOE ε4-which is ance...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgen.1012285

Genetic impact of non-consanguineous marriages in Saudi Arabia.

Mohammed Alyahya, Taghrid Aloraini, Youseef Al-Harbi, Lamia Alsubaie et al. • Journal of Biochemical and Clinical Genetics (2022)

Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients and clinicians. The aim of this study was to estimate the hit rate of the non-consanguineous population. Mor...

DOAJ Open Access (DOAJ) DOI: 10.24911/JBCGenetics/183-1664872492

Cracking rare disorders: a new minimally invasive RNA-seq protocol

Laurenz De Cock, Erika D’haenens, Lies Vantomme, Lynn Backers et al. • npj Genomic Medicine (2025)

Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41525-025-00502-7

Expert projections on the development and application of bioenergy with carbon capture and storage technologies

Tobias Heimann, Lara-Sophie Wähling, Tomke Honkomp, Ruth Delzeit et al. • Environmental Research Letters (2025)

Bioenergy with carbon capture and storage (BECCS) is a crucial element in most modelling studies on emission pathways of the Intergovernmental Panel on Climate Change to limit global warming. BECCS can substitute fossil fuels in energy prod...

DOAJ Open Access (DOAJ) DOI: 10.1088/1748-9326/ada16f

Medico-Legal Applications of the Human Microbiome and Critical Issues Due to Environmental Transfer: A Review

Giulia Ricchezze, Erika Buratti, Francesco De Micco, Mariano Cingolani et al. • Microorganisms (2024)

Microbiome has recently seen an increase in its forensic applications. It could be employed to identify a suspect when DNA is not available; it can be used to establish postmortem interval (PMI). Furthermore, it could prove to be fundamenta...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms12122424

Genome-based development of 15 microsatellite markers in fluorescent multiplexes for parentage testing in captive tigers

Xiao Zhao, Qiguan Qiu, Chang Li, Dongke Fu et al. • PeerJ (2020)

As one of the most endangered species, tiger (Panthera tigris) inbreeding has become an urgent issue to address. Using a microsatellite (short tandem repeat, STR) identification system, paternity testing may be helpful to avoid inbreeding i...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.8939

Autism Spectrum Disorder and collective catering service: results of the pilot study FOOD-AUT

Maria Vittoria Conti, Sara Santero, Chiara Breda, Sara Basilico et al. • Frontiers in Nutrition (2024)

ObjectiveIndividuals with Autism Spectrum Disorder (ASD) often exhibit a low dietary diversity due to food selectivity that leads them to a marked preference for high-energy-density food, exposing them to risk of malnutrition. Despite these...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2023.1298469

Natural Polyphenols for the Preservation of Meat and Dairy Products

Hammad Ullah, Yaseen Hussain, Cristina Santarcangelo, Alessandra Baldi et al. • Molecules (2022)

Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, sa...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27061906