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Metabolomic Profile Alterations Associated with the SLC16A11 Risk Haplotype Following a Lifestyle Intervention in People With Prediabetes

Magdalena Sevilla-González, Maria Fernanda Garibay-Gutiérrez, Arsenio Vargas-Vázquez, Andrea Celeste Medina-García et al. • Current Developments in Nutrition (2024)

Background: A risk haplotype in SLC16A11 characterized by alterations in fatty acid metabolism emerged as a genetic risk factor associated with increased susceptibility to type 2 diabetes (T2D) in Mexican population. Its role on treatment r...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.cdnut.2024.104444

Genetic Markers of Adaptation of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Transmission by American Vectors Identified in the Genomes of Parasites from Haiti and South America

Massimiliano S. Tagliamonte, Charles A. Yowell, Maha A. Elbadry, Jacques Boncy et al. • mSphere (2020)

ABSTRACT The malaria parasite, Plasmodium falciparum, was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries. During this period, more than 12 million Africans w...

DOAJ Open Access (DOAJ) DOI: 10.1128/mSphere.00937-20

Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target

Xiaofeng Duan, Stephen Iwanowycz, Soo Ngoi, Megan Hill et al. • Frontiers in Oncology (2021)

During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2021.629846

Maternal cardiovascular adaptation to twin pregnancy: a population-based prospective cohort study

Maria C. Adank, Zoe A. Broere-Brown, Romy Gonçalves, M. Kamran Ikram et al. • BMC Pregnancy and Childbirth (2020)

Abstract Background In women with singleton pregnancies, maternal adaptation is considered a stress test for later life cardiovascular disease. The aim of this study was to assess maternal adaptation in women with twin pregnancies compared ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12884-020-02994-w

The JWST Resolved Stellar Populations Early Release Science Program. VIII. The Spatially Resolved Star Formation History of WLM

Roger E. Cohen, Kristen B. W. McQuinn, Alessandro Savino, Max J. B. Newman et al. • The Astrophysical Journal (2025)

Radial stellar population gradients within dwarf galaxies provide a promising avenue for disentangling the drivers of galaxy evolution, including environment. Within the Local Volume, radial stellar age gradient slopes correlate with intera...

DOAJ Open Access (DOAJ) DOI: 10.3847/1538-4357/adb61d

Highly efficient photonic PCR system based on plasmonic heating of gold nanofilms

Joshua Nabuti, Ahmed Rashad Fath Elbab, Ahmed Abdel-Mawgood, Matsushita Yoshihisa et al. • Biosensors and Bioelectronics: X (2023)

The polymerase chain reaction (PCR) is a standard molecular method that has the potential to solve the need for accurate, viable, and immediate infectious pathogen detection at point-of-care (POC) centers in different fields such as pathoge...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.biosx.2023.100346

Artificial intelligence in clinical medicine: a state-of-the-art overview of systematic reviews with methodological recommendations for improved reporting

Giovanni Morone, Giovanni Morone, Luigi De Angelis, Luigi De Angelis et al. • Frontiers in Digital Health (2025)

Medicine has become increasingly receptive to the use of artificial intelligence (AI). This overview of systematic reviews (SRs) aims to categorise current evidence about it and identify the current methodological state of the art in the fi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fdgth.2025.1550731

AI-generated draft replies to patient messages: exploring effects of implementation

Charlotte M. H. H. T. Bootsma-Robroeks, Charlotte M. H. H. T. Bootsma-Robroeks, Jessica D. Workum, Jessica D. Workum et al. • Frontiers in Digital Health (2025)

IntroductionThe integration of Large Language Models (LLMs) in Electronic Health Records (EHRs) has the potential to reduce administrative burden. Validating these tools in real-world clinical settings is essential for responsible implement...

DOAJ Open Access (DOAJ) DOI: 10.3389/fdgth.2025.1588143

A rule-based stemmer for Arabic Gulf dialect

Belal Abuata, Asma Al-Omari • Journal of King Saud University: Computer and Information Sciences (2015)

Arabic dialects arewidely used from many years ago instead of Modern Standard Arabic language in many fields. The presence of dialects in any language is a big challenge. Dialects add a new set of variational dimensions in some fields like ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jksuci.2014.04.003

Valorisation of agri-food by-products into bioactive compounds: Green extraction, microbial biotransformation and circular biorefinery strategies

Arjun Mohanakumar, Massimiliano Rinaldi, Jasmine Hadj Saadoun, Camilla Lazzi et al. • Applied Food Research (2026)

Agri-food processing generates large volumes of by-products that remain insufficiently exploited despite their content of phenolic compounds, peptides, polysaccharides, carotenoids, dietary fibres and other functional constituents. These si...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.afres.2026.102511

Humor and Resistance in Pakistani Corporate Memes

Aneeqa Ahmad, Musarrat Azher, Muhammad Asim Mahmood • NUML Journal of Critical Inquiry (2025)

This study aims at investigating how humor is constructed in corporate memes through cognitive mechanisms and how corporate memes are used as a collective voice by Pakistani employees to express discontent with their work culture and organi...

DOAJ Open Access (DOAJ) DOI: 10.52015/numljci.v23iII.296

A Comprehensive Review on 3D Object Detection and 6D Pose Estimation With Deep Learning

Sabera Hoque, Md. Yasir Arafat, Shuxiang Xu, Ananda Maiti et al. • IEEE Access (2021)

Nowadays, computer vision with 3D (dimension) object detection and 6D (degree of freedom) pose assumptions are widely discussed and studied in the field. In the 3D object detection process, classifications are centered on the object&#x2019;...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2021.3114399

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

Linda Nötzold, Lukas Frank, Minakshi Gandhi, Maria Polycarpou-Schwarz et al. • Scientific Reports (2017)

Abstract In recent years, long non-coding RNA (lncRNA) research has identified essential roles of these transcripts in virtually all physiological cellular processes including tumorigenesis, but their functions and molecular mechanisms are ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-02357-0

Computer vision and machine‐learning techniques for quantification and predictive modeling of intracellular anticancer drug delivery by nanocarriers

Sanjay Goswami, Kshama D. Dhobale, Ravindra D. Wavhale, Barnali Goswami et al. • Applied AI Letters (2022)

Abstract The field of cancer nanomedicine has made significant progress, but its clinical translation is impeded by many challenges, such as the difficulty in analyzing intracellular anticancer drug release by the nanocarriers due to the la...

DOAJ Open Access (DOAJ) DOI: 10.1002/ail2.50