Academic Articles & Research Papers

Early Retinal Microvascular Alterations in Young Type 1 Diabetic Patients without Clinical Retinopathy

The purpose of this study is to identify and quantify preclinical changes with the help of optical coherence tomography angiography (OCTA) within the retinal microcirculation of young type 1 diabetes (T1D) patients without clinical signs of...

Datasets describing hydrogel properties and cellular metrics for modeling of tumor dormancy

Breast cancer dormancy is an underlying challenge toward targeting and controlling metastatic recurrence and disease progression. Development of engineered, well-defined in vitro models is necessary to systematically recapitulate tumor dorm...

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

A genome-wide association study on meat consumption in a Japanese population: the Japan Multi-Institutional Collaborative Cohort study

Recent genome-wide association studies (GWAS) on the dietary habits of the Japanese population have shown that an effect rs671 allele was inversely associated with fish consumption, whereas it was directly associated with coffee consumption...

Accelerated maximum likelihood parameter estimation for stochastic biochemical systems

Abstract Background A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data i...

Integrating machine learning algorithms and explainable artificial intelligence approach for predicting patient unpunctuality in psychiatric clinics

This study addresses patient unpunctuality, a major concern affecting patient waiting time, resource utilization, and quality of care. We develop and compare four machine learning models, including multinomial logistic regression, decision ...

Swarm v2: highly-scalable and high-resolution amplicon clustering

Previously we presented Swarm v1, a novel and open source amplicon clustering program that produced fine-scale molecular operational taxonomic units (OTUs), free of arbitrary global clustering thresholds and input-order dependency. Swarm v1...

BirdsEyeView (BEV): graphical overviews of experimental data

Abstract Background Analyzing global experimental data can be tedious and time-consuming. Thus, helping biologists see results as quickly and easily as possible can facilitate biological research, and is the purpose of the software we descr...

Lecture notes in medical informatics

Challenges for Medical Informatics as an Academic Discipline

In March 2001, twenty members of the informatics community gathered in Madrid, Spain, to discuss the state of our field as an academic discipline and the challenges that university-based workers in health informatics face.The workshop, held...

The role of medical informatics in the management of medical information

With progress in information and communication technology, medical information has been converted to digital formats and stored and managed using computer systems. The construction, management, and operation of medical information systems a...

What is medical informatics?

Medical Informatics as a Discipline at the Beginning of the 21st Century

OBJECTIVES: To analyse the present situation of the discipline medical informatics and to propose actions for change. METHODS: Evaluation of the current situation mainly based on anecdotal evidence. RESULTS: The difference between the scien...

Impact of medical informatics on medical education.

In recent years, medical informatics has become a well-recognized branch of medicine. It is a multidisciplinary science that combines information technology and various specialties of medicine. The impact of medical informatics on medical e...

Is telemedicine a subset of medical informatics?

Informatics has a key characteristic of a new discipline in a technically transient environment--there is no universal definition of it. This is not surprising, given its complex and diverse nature. In a broad sense informatics is the inter...

Medical Informatics as a Scientific Discipline

Side effects and responsibility of medical informatics

[Medical informatics--today and tomorrow].

The status of medical informatics, a comparatively new biomedical discipline beginning to develop in the second half of the 20th century, is described at the transition into the 21st century. The appearance of new information and communicat...

Medical informatics meets medical education

Medical Informatics