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CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia

Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ (2020)

Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.9796

Spray dried inulin–sodium carboxymethylcellulose microcarriers with solid-to-colloidal transition: Development for foliar delivery of polyphenol-rich extract

Rita Patrizia Aquino, Teresa Mencherini, Pierluigi Mazzei, Tiziana Esposito et al. • Carbohydrate Polymer Technologies and Applications (2025)

This study reports on the development of a carbohydrate-based spray-dried microparticulate system (F-CHES) conceived for the stabilization and foliar delivery of polyphenol-rich plant extracts for sustainable phyto defense applications. Che...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.carpta.2025.101023

Investigating the performance of the fluorescent sensor g-C3N4/Fe/Cu in detecting the Tenofovir drug

Nafiseh Hajian Afarani, Fatemeh Keshavarzi, Kahin Shahanipour, Seyed Amir Zarei • Scientific Reports (2025)

Abstract Tenofovir is an antiviral drug that prevents the replication of AIDS and hepatitis B viruses. To minimize the harmful side effects of the drug on the body, it is essential to determine its precise concentration in the blood. Fluore...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-08877-4

Cerebrospinal fluid-stem cell interactions may pave the path for cell-based therapy in neurological diseases

Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy (2018)

Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13287-018-0807-3

Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults

Müjgan Ercan, Emiş Deniz Akbulut, Ayşen Caniklioğlu, Esra Fırat Oğuz et al. • Journal of Mass Spectrometry and Advances in the Clinical Lab (2025)

Introduction: Free amino acid (FAA) analysis plays a crucial role in diagnosing and monitoring inborn errors of metabolism, assessing nutritional status, and identifying metabolic imbalances associated with various diseases. This study aime...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jmsacl.2025.04.010

OCCURENCE OF OESTRUS OVIS IN GOATS IN PALAKKAD, KERALA AND ITS SUCCESSFUL MANAGEMENT

Bindu Lakshmanan, K.T. Rajimon, K.M. Manjusha, P. Muhammed Shiyas et al. • Journal of Veterinary and Animal Sciences (2019)

Oestrus ovis is a larviparous protelean fly whose larvae parasitize the nasal cavities and adjoining sinuses of sheep and goats. It is primarily a widespread infestation of sheep and rarely occurs in goat, camel, deer, reindeer, elk and ib...

DOAJ Open Access (DOAJ)

Evaluation of Lipid Profile and Inflammatory Marker in Patients with Gastric Helicobacter pylori Infection, Ethiopia

Temesgen GB, Menon M, Gizaw ST, Yimenu BW et al. • International Journal of General Medicine (2022)

Gelagey Baye Temesgen,1 Menakath Menon,2 Solomon Tebeje Gizaw,2 Bayu Wondimneh Yimenu,1 Melaku Mekonen Agidew3 1Department of Biomedical Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Medical Biochemistry School o...

DOAJ Open Access (DOAJ)

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Impact of Myocardial Ischemia and Revascularization by Percutaneous Coronary Intervention on Circulating Level of Soluble ST2

Alkhateeb A, Mahmoud HEM, AK M, Hassan MH et al. • Vascular Health and Risk Management (2023)

Areej Alkhateeb,1 Hossam Eldin M Mahmoud,1 Mohammed AK,1 Mohammed H Hassan,2 Abdel Rahim Mahmoud Muddathir,3 Ahmed G Bakry1 1Cardiology Division of Internal Medicine Department, South Valley University Hospital, Faculty of Medicine, South V...

DOAJ Open Access (DOAJ)

GROSS ANATOMICAL STUDIES ON THE CRANIUM OF BARRED JUNGLE OWLET (Glaucidium radiatum malabaricum)

K. B. Sumena, N. S. Sunilkumar, K. M. Lucy, S. Maya et al. • Journal of Veterinary and Animal Sciences (2019)

Present study was conducted with the aim to understand the morphological features of skull of barred jungle owlet.The head of the owletwascollected from the specimen brought for post-mortem, processed and morphological studies were conduct...

DOAJ Open Access (DOAJ)

Synthesis and properties of fluorene based small molecule acceptors containing aromatic malononitrile functionalities

Sarah E. Brock, Dariia Yehorova, Brycelyn M. Boardman • Results in Chemistry (2022)

Four novel small molecule acceptors (SMA) with fluorene-based cores were synthesized with terminal phenyl, thienyl, and furyl malononitrile groups in good yields. The products were obtained from a two-step reaction of 2,2′-(9,9-dioctyl-9H-f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2022.100320

Water and soil pollution as determinant of water and food quality/contamination and its impact on female fertility

Justin Rashtian, Diana E. Chavkin, Zaher Merhi • Reproductive Biology and Endocrinology (2019)

Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse repr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12958-018-0448-5

Review on: Women with Polycystic Ovary Syndrome

Neelam Gusain, Ashish P. Anjankar, Ranjit S. Ambad, Roshan K. Jha et al. • Journal of Pharmacy and Bioallied Sciences (2025)

One of the biggest health issues facing women in their childbearing years worldwide is polycystic ovarian syndrome, or PCOS. PCOS is a prevalent endocrine condition with well-known negative effects on metabolism, reproduction, and cardiovas...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.jpbs_1995_24

A Kalman-Jacobi hybrid model for game theory: a fuzzy logic approach to financial market competition

Alireza Azarberahman, Mahmoodreza Mohammadnejadi Modi • Journal of Business and Socio-Economic Development (2025)

PurposeThis research examines the structure of financial markets by integrating game theory and fuzzy logic. The objective is to develop a differential game model that analyzes competition among financial firms within a specific industry.De...

DOAJ Open Access (DOAJ) DOI: 10.1108/JBSED-03-2024-0030

Functional Assessment of the Quality of Human Hepatocyte Preparations for Cell Transplantation

María Teresa Donato, Agustín Lahoz, Sandra Montero, Ana Bonora et al. • Cell Transplantation (2008)

Hepatocyte transplantation is an alternative therapy to orthotopic liver transplantation for the treatment of liver diseases. Good quality freshly isolated or cryopreserved human hepatocytes are needed for clinical transplantation. However,...

DOAJ Open Access (DOAJ) DOI: 10.3727/096368908787236620