Academic Articles & Research Papers

Pancreatic Islet Cell Hormones: Secretion, Function, and Diabetes Therapy

ABSTRACT The pancreatic islets of Langerhans, which are composed of α, β, δ, ε, and PP cells, orchestrate systemic glucose homeostasis through tightly regulated hormone secretion. Although the precise mechanisms involving β cells in the ons...

Language editing in the artificial intelligence era: achieving epistemic integrity—an expanded Korean translation.

Oxytocin Signalling in Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia and Overactive Bladder Syndrome: A Narrative Review

Lower urinary tract symptoms (LUTSs) associated with benign prostatic disease and overactive bladder syndrome (OAB) substantially impair quality of life. This narrative review evaluates oxytocin receptor (OXTR) localisation, signalling, and...

Translation, cross-cultural adaptation and face validity of an educational brochure for Spanish women with primary dysmenorrhea.

Towards Transparency by Design for Artificial Intelligence

In this article, we develop the concept of Transparency by Design that serves as practical guidance in helping promote the beneficial functions of transparency while mitigating its challenges in automated-decision making (ADM) environments....

Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data

Abstract Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease lands...

Translational modelling of human microglia from cultures to chimeras.

Designing novel linagliptin analogs through combined generative artificial intelligence, molecular docking, molecular dynamics simulation, and binding energy estimation for targeting fibroblast activation protein

Fibroblast activation protein (FAP) is a highly specific biomarker overexpressed in cancer-associated fibroblasts, making it a promising diagnostic target. Developing novel high-affinity molecular probes for FAP-targeted diagnostics remains...

Artificial Intelligence in Pathology

As in other domains, artificial intelligence is becoming increasingly important in medicine. In particular,deep learning-based pattern recognition methods can advance the field of pathology byincorporating clinical, radiologic, and genomic ...

Artificial Intelligence and Personalized Medicine

From molecular pathways to nanocarrier design: a translational framework for lipid-based nanoparticles in Alzheimer's disease.

The co-curation of collective memory: artificial intelligence, Holocaust survivor testimony and the contribution of museum educators

Holocaust survivor testimony is increasingly being preserved using emerging technologies in preparation for a post-survivor era. A key approach to this process is exemplified by the Dimensions in Testimony platform developed by the Universi...

Biomaterial Engineering for Spatiotemporal Regulation of Exosome Functions: From Design Principles to Key Applications in Regenerative Medicine

As natural nanoscale intercellular messengers, exosomes exhibit considerable potential in modulating inflammation, angiogenesis, immunoregulation, and tissue remodeling, making them attractive candidates for regenerative medicine. However, ...

Information leakage and performance overestimation in EEG-based schizophrenia detection: evidence from literature and empirical analyses.

Validity and reliability of the Chinese translation of the attitude scale towards the use of artificial intelligence technologies in nursing (ASUAITIN)- a cross-sectional study

Abstract Aim This study aimed to test the psychometric properties of the Attitudes Toward Artificial Intelligence in Nursing Scale (ASUAITIN) in Chinese culture. Methods A convenience sampling method was employed to recruit 499 clinical nur...

Exercise-induced metabolic reprogramming in lung cancer and its translational implications for therapeutic advancement.

Convergence of Artificial Intelligence and Wearables in Strength Training and Performance Monitoring: A Scoping Review

Background: Strength training (ST) is essential for enhancing athletic performance and reducing injury risk, yet traditional monitoring relies heavily on subjective assessment, limiting objective and individualized evaluation. Objective: Th...

Cost-effective, open-source, automated apparatus for testing transitive inference in mice

Abstract Transitive inference is a form of reasoning that relies on prior knowledge and benefits survival in diverse species. While initially designed for humans, the transitive inference task has been adapted for mice, allowing for integra...

Opportunities and Challenges in FLASH Radiotherapy: Focusing on Normal Tissue Protection Effects and Clinical Translation Bottleneck.

Correction to "Impact of Stress Hyperglycemia Ratio on Adverse Outcomes in Patients With Chronic Thromboembolic Pulmonary Hypertension".