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Showing 20 of 992 academic articles

Sequential Portal Vein Embolization and Percutaneous Radiofrequency Ablation for Future Liver Remnant Growth: A Minimally Invasive Alternative to ALPPS Stage-1 in Treatment of Hepatocellular Carcinoma

Qiang Wang, Qiang Wang, Yujun Ji, Torkel B. Brismar et al. • Frontiers in Surgery (2021)

Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for stage...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsurg.2021.741352

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Water and soil pollution as determinant of water and food quality/contamination and its impact on female fertility

Justin Rashtian, Diana E. Chavkin, Zaher Merhi • Reproductive Biology and Endocrinology (2019)

Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse repr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12958-018-0448-5

Green Banking Disclosure and Financial Trade-Offs: Evidence from Indonesia’s Banking Sector

Nafis Dwi Kartiko, Amrie Firmansyah • Buletin Ekonomi Moneter dan Perbankan (2026)

This study explores the relationship between green banking disclosure, firm performance, and firm value, with firm size and age as moderating variables. The study analyzed 578 observations from 43 banking companies in Indonesia. The finding...

DOAJ Open Access (DOAJ) DOI: 10.59091/2460-9196.2145

Evaluating key predictors of breast cancer through survival: a comparison of AFT frailty models with LASSO, ridge, and elastic net regularization

Senyefia Bosson-Amedenu, Emmanuel Ayitey, Francis Ayiah-Mensah, Luyton Asare • BMC Cancer (2025)

Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12885-025-14040-z

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer (2021)

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-021-01362-2

Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data

Sangmo Hong, Kyungdo Han, Cheol-Young Park • Endocrinology and Metabolism (2025)

Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap, we conducted five studies usin...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2024.2285

Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana

Eric Nyarko, Irene A. Kretchy, Grace Lovia Allotey-Babington, Adwoa Oforiwaa Kwakye et al. • BMC Infectious Diseases (2026)

Abstract Background Poor adherence to antiretroviral therapy (ART) continues to undermine HIV treatment outcomes in sub-Saharan Africa, including Ghana. Objective This study aimed to quantify ART treatment adherence among people living with...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12879-026-13836-z

Ranking of treatments in network meta-analysis: incorporating minimally important differences

Tristan Curteis, Augustine Wigle, Christopher J. Michaels, Adriani Nikolakopoulou • BMC Medical Research Methodology (2025)

Abstract Background In network meta-analysis (NMA), the magnitude of difference between treatment effects is typically ignored in the calculation of ranking metrics, such as probability best and surface under the cumulative ranking curve (S...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-025-02499-0

Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)

Susan A. Kirkland, Lauren E. Griffith, Urun Erbas Oz, Mary Thompson et al. • BMC Public Health (2023)

Abstract Background Older adults have been disproportionately impacted by COVID-19 and related preventative measures undertaken during the pandemic. Given clear evidence of the relationship between loneliness and health outcomes, it is impe...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-023-15807-4

BUGSnet: an R package to facilitate the conduct and reporting of Bayesian network Meta-analyses

Audrey Béliveau, Devon J. Boyne, Justin Slater, Darren Brenner et al. • BMC Medical Research Methodology (2019)

Abstract Background Several reviews have noted shortcomings regarding the quality and reporting of network meta-analyses (NMAs). We suspect that this issue may be partially attributable to limitations in current NMA software which do not re...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-019-0829-2

The beneficial effects of menopausal hormone therapy on renal survival in postmenopausal Korean women from a nationwide health survey

Shin Young Ahn, Yoon Jin Choi, Jieun Kim, Gang Jee Ko et al. • Scientific Reports (2021)

Abstract Several studies have demonstrated the nephroprotective effects of estrogen on renal damage. In light of the inconsistent results of previous findings, this study aims to evaluate the in-depth role of menopausal hormone therapy (MHT...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-93847-9

Factors Affecting High Body Weight Variability

Kyungdo Han, Mee Kyoung Kim • Journal of Obesity & Metabolic Syndrome (2023)

Background : High body weight variability (BWV) is associated with many metabolic and cardiovascular diseases in adults. The study was designed to explore the baseline characteristics associated with high BWV. Methods : Using a nationally r...

DOAJ Open Access (DOAJ) DOI: 10.7570/jomes22063

Clustering of Unhealthy Lifestyle and the Risk of Adverse Events in Patients With Atrial Fibrillation

So-Ryoung Lee, Eue-Keun Choi, Eue-Keun Choi, Sang-Hyeon Park et al. • Frontiers in Cardiovascular Medicine (2022)

BackgroundLittle is known regarding the risk of clinical outcomes depending on the clustering of lifestyle behaviors after atrial fibrillation (AF) diagnosis. This study evaluated the association between a cluster of healthy lifestyle behav...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2022.885016

Patient and allograft outcomes after kidney transplant for the Indigenous patients in the United States.

Regan Seipp, Nan Zhang, Sumi Sukumaran Nair, Hasan Khamash et al. • PLoS ONE (2021)

BackgroundThe objective is to assess cardiovascular (CV), malignancy, infectious, graft outcomes and tacrolimus levels for the Indigenous patients compared to Whites after kidney transplant (KTx).Methods165 Indigenous and 165 White patients...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0244492

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Salmaan Keshavjee, Meredith B Brooks, Tom Nicholson, Viswanath Pingali • BMJ Open (2023)

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-070717

Response Surface Analysis: A Tutorial for Examining Linear and Curvilinear Effects

Antonio Carlos Rodrigues • RAC: Revista de Administração Contemporânea (2021)

Context: response surface analysis (RSA) is an approach that allows examining the extent to which combinations of two predictive variables relate to one outcome variable. The method is particularly interesting in cases where (in)congruence ...

DOAJ Open Access (DOAJ) DOI: 10.1590/1982-7849rac2021200293.en