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Roles of Rap1 signaling in tumor cell migration and invasion

Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine (2017)

Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...

DOAJ Open Access (DOAJ) DOI: 10.20892/j.issn.2095-3941.2016.0086

Integrated-Hybrid Framework for Connected and Autonomous Vehicles Microscopic Traffic Flow Modelling

Ammar Jafaripournimchahi, Yingfeng Cai, Hai Wang, Lu Sun et al. • Journal of Advanced Transportation (2022)

In this study, a novel traffic flow modeling framework is proposed considering the impact of driving system and vehicle mechanical behavior as two different units on the traffic flow. To precisely model the behavior of Connected and Autonom...

DOAJ Open Access (DOAJ) DOI: 10.1155/2022/2253697

First archeological exploration of the Roman mines of Sierra Morena: El Centenillo (Baños de la Encina, Jaén)

Luis ARBOLEDAS MARTÍNEZ, Jean-Marc FABRE, Julien MANTENANT • Zephyrus (2012)

At the mining area of El Centenillo (Baños de la Encina, Jaén) during several archaeological superficial studies and surveys a great amount of ancient fossilized miners works remains have been found inside the “socavones” (mines entrances) ...

DOAJ Open Access (DOAJ)

The song of air and water: Acoustic experiments with an Ecuadorian Whistle Bottle (c.900 BC–100 BC)

Mónica Amparo Ayala Esparza, Galo Fernando Gallardo Carrillo, Miguel Molina-Alarcón • Internet Archaeology (2019)

In Ecuador, bottles as containers for liquids appeared in the Late Formative period at the end of the Machalilla culture (1600 BC to 800 BC). Whistle bottles were created and perfected during the Chorrera culture (900 BC to 100 BC), and fin...

DOAJ Open Access (DOAJ) DOI: 10.11141/ia.52.2

The Numerical Solution of Fractional Parabolic Partial Integro-Differential Eequations by Gaussian and Inverse Multiquadric Radial Basis Functions

F. S. Aghaei Maybodi, M. H. Heydari, F. M. Maalek Ghaeini, M. H. Akrami • پژوهش‌های ریاضی (2021)

Introduction Many mathematical formulations of physical phenomena contain integro-differential equations. These equations arise in fluid dynamics, biological models, chemical kinetics, ecology, control theory of financial mathematics, aeros...

DOAJ Open Access (DOAJ)

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer (2021)

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-021-01362-2

Changes in the geographical distribution of youth poverty and social exclusion in EU member countries between 2008 and 2017

Šoltés Erik, Vojtková Mária, Šoltésová Tatiana • Moravian Geographical Reports (2020)

With respect to the fulfillment of the objectives of the Europe 2020 strategy, the threat of poverty and social exclusion has not been sufficiently reduced in the European Union (EU) over the past decade, and large regional disparities pers...

DOAJ Open Access (DOAJ) DOI: 10.2478/mgr-2020-0001

An artificial neural network-based model for predicting paratransit travel time

George Ukam, Charles Adams, Atinuke Adebanji, Williams Ackaah • Cogent Engineering (2024)

The nature of paratransit services makes for increased uncertainty in trip time, leading to reported unreliability and dissatisfaction by the users. While providing travel information has proved helpful in formal bus services and has been r...

DOAJ Open Access (DOAJ) DOI: 10.1080/23311916.2024.2386383

Ozonation, electrochemical, and biological methods for the remediation of malachite green dye wastewaters: A mini review

Peter Olusakin Oladoye, Timothy Oladiran Ajiboye, Wycliffe Chisutia Wanyonyi, Elizabeth Oyinkansola Omotola et al. • Sustainable Chemistry for the Environment (2023)

The extensive usage of malachite green (MG) dyes in the fish and dye industries cause serious water pollution, leading to catastrophic effects on living organisms and the environment. In addressing the challenges of health risks related to ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.scenv.2023.100033

Extremes of Product of Gaussian Random Variables

Džiugas Chvoinikov, Svyatoslav Novikov, Jonas Šiaulys • Axioms (2026)

We investigate the asymptotic behavior of the product of Gaussian random variables, with a focus on tail probabilities. Although sums of normal variables are well understood through classical limit theorems, their products exhibit significa...

DOAJ Open Access (DOAJ) DOI: 10.3390/axioms15060425

Integration of Hydrological Model and Time Series Model for Improving the Runoff Simulation: A Case Study on BTOP Model in Zhou River Basin, China

Qintai Xiao, Li Zhou, Xin Xiang, Lingxue Liu et al. • Applied Sciences (2022)

Improving the accuracy of runoff simulations is a significant focus of hydrological science for multiple purposes such as water resources management, flood and drought prediction, and water environment protection. However, the simulated run...

DOAJ Open Access (DOAJ) DOI: 10.3390/app12146883

Coastal wave-energy attenuation by artificial wooden fences deployed for mangrove restoration: an experimental study

Anping Shu, Jiapin Zhu, Baoshan Cui, Le Wang et al. • Frontiers in Marine Science (2023)

By offering natural protection along offshore wetlands, mangroves play a crucial role in providing great ecological and economic benefits to local communities. However, mangroves are currently facing an increasing threat of decline worldwid...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmars.2023.1165048

Representing and Visualizing Archaeology. The Contribution of Graphic Sciences to Research in Archaeology

Enrico Cicalò, Michele Valentino • img journal (2025)

This article discusses the role of images in archaeological disciplines and the contribution that graphic sciences can make to research in this subject area. In archaeology, and not only, ‘visualization’ differs significantly from the more ...

DOAJ Open Access (DOAJ) DOI: 10.6092/issn.2724-2463/18884