Academic Articles & Research Papers

Machine learning in pain research

1. Introduction Pain and pain chronification are incompletely understood and unresolved medical problems that continue to have a high prevalence.14 It has been accepted that pain is a complex phenomenon.2,32,72 Contemporary methods of compu...

Machine Learning for Detection and Diagnosis of Disease

Machine learning offers a principled approach for developing sophisticated, automatic, and objective algorithms for analysis of high-dimensional and multimodal biomedical data. This review focuses on several advances in the state of the art...

Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis

Abstract Background Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-st...

Interpretable machine learning to detect well integrity issues

The problem of timely and accurate evaluation of well integrity is becoming increasingly relevant in the context of mature field development, high wellstream water cut, and a growing number of old wells. For production casing diagnostics, g...

Precise diagnosis of Alzheimer’s disease based on sex-specific gray matter characteristics

IntroductionThere are notable sex differences in the gray matter of Alzheimer’s disease(AD) patients’ brains, but current evidence is insufficient to prove these differences aid diagnosis effectively.MethodsMultivariate analysis of variance...

Machine Learning and the Future of Cardiovascular Care

The role of physicians has always been to synthesize the data available to them to identify diagnostic patterns that guide treatment and follow response. Today, increasingly sophisticated machine learning algorithms may grow to support clin...

Introduction to machine learning: k-nearest neighbors

Machine learning techniques have been widely used in many scientific fields, but its use in medical literature is limited partly because of technical difficulties. k-nearest neighbors (kNN) is a simple method of machine learning. The articl...

Automated speech-fluency explanations for schizophrenia diagnosis

Abstract Schizophrenia is a chronic and severe mental disorder that still relies on time-intensive, clinician-administered assessments. Although several automated approaches have been proposed to support diagnosis, these systems often lack ...

Exploring the application and challenges of fNIRS technology in early detection of Parkinson’s disease

BackgroundParkinson’s disease (PD) is a prevalent neurodegenerative disorder that significantly benefits from early diagnosis for effective disease management and intervention. Despite advancements in medical technology, there remains a cri...

Towards a physics informed digital twin to predict cerebral blood flow and cerebral vascular regulation

Abstract Cerebral blood flow is essential for brain function and is governed by cerebral perfusion pressure and physiological mechanisms collectively referred to as cerebral vascular regulation (CVR). Direct measurement of cerebral blood fl...

Machine learning and medical education

Artificial intelligence (AI) driven by machine learning (ML) algorithms is a branch in computer science that is rapidly gaining popularity within the healthcare sector. Recent regulatory approvals of AI-driven companion diagnostics and othe...

Operational Digital Shadow for Onshore Wind Energy Systems

Accurate, uncertainty-aware estimation of instantaneous wind turbine output is a prerequisite for integrating onshore assets into low-emission energy systems, where operational monitoring, energy-performance verification, and cooperative as...

Machine learning for precision medicine

Precision medicine is an emerging approach to clinical research and patient care that focuses on understanding and treating disease by integrating multi-modal or multi-omics data from an individual to make patient-tailored decisions. With t...

Diagnostic utility of plasma heparin-binding protein and procalcitonin among patients with bacterial infections: a single-center retrospective study.

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

ABSTRACT Dysregulated protein glycosylation is a hallmark of cancer, and systematic investigation of glycosylation patterns is crucial for identifying biomarkers. However, current glycoproteomic studies are constrained by the limited quanti...

Towards instance-wise calibration: local amortized diagnostics and reshaping of conditional densities (LADaR)

Key science questions, such as galaxy distance estimation and weather forecasting, often require knowing the full predictive distribution of a target variable Y given complex inputs X . Despite recent advances in machine learning and physic...

Hybrid machine learning and 3D numerical modeling-based multi-objective optimization of geosynthetic-reinforced pile-supported embankments

Efficient and reliable design of Geosynthetic Reinforced Pile-Supported (GRPS) embankments on soft ground remains challenging due to the complex nonlinear soil–structure interaction and the high computational cost of repeated numerical anal...

PCPAm - A dataset of histopathological images of penile cancer for classification tasksZenodo

Penile cancer has an incidence strongly linked to sociocultural factors, being more common in underdeveloped countries like Brazil, where it represents approximately 2% of cancers affecting men. This dataset was created to address the scarc...

Identification of arachidonic acid metabolism-related diagnostic markers in heart failure based on bioinformatics analysis and machine learning

BackgroundHeart failure (HF) represents the terminal phase of multiple cardiovascular conditions and is associated with significant morbidity and mortality rates. Arachidonic acid (AA), an essential fatty acid, plays a crucial role in modul...

Machine learning-based diagnostic prediction of minimal change disease: model development study

Abstract Minimal change disease (MCD) is a common cause of nephrotic syndrome. Due to its rapid progression, early detection is essential; however, definitive diagnosis requires invasive kidney biopsy. This study aims to develop non-invasiv...