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Recent advances in benzo[a]phenoxazine-based fluorescent probes: a review and perspectives

Kalayou Hiluf Gebremdhin, Mebrahtom Gebrelibanos Hiben, Hagos Feleke Gebremariam, Hagos Hailu Kassegn et al. • Journal of Photochemistry and Photobiology (2026)

Benzo[a]phenoxazine (BPO) based molecules have been recently emerged as a new class of near-infrared (NIR) fluorophore for image-guided diagnosis in cancer research. The successful application of BPOs as NIR fluorophore in biomedical resear...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpap.2026.100280

Changes in the nonlinear and viscoelastic mechanical properties of the rat lamina cribrosa under chronic high intraocular pressure

Yuqing Wang, Liu Liu, Liu Liu, Jingxi Zhang et al. • Frontiers in Bioengineering and Biotechnology (2026)

IntroductionThe lamina cribrosa (LC) in the optic nerve head is the initial site of glaucomatous optic nerve injury. Under high intraocular pressure (IOP), the deformation of the LC compresses the retinal ganglion cell (RGC) axons passing t...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2026.1875609

A Prospective, Randomized Trial Comparing Hydromorphone and Nalbuphine for Postcesarean Patient-Controlled Analgesia and Developing a Risk Prediction Model for Inadequate Analgesia

Zhang K, Sun J, Zhang C, Jiao B et al. • Drug Design, Development and Therapy (2025)

Kaiwen Zhang,1,* Jiaoli Sun,1,* Caixia Zhang,2 Bo Jiao,1 Wencui Zhang,1 Shangchen Yu,1 Xueqin Cao,1 Zhiqiang Zhou,1 Guanglei Zhang,1 Xianwei Zhang1 1Department of Anesthesiology and Pain Medicine,Hubei Key Laboratory of Geri...

DOAJ Open Access (DOAJ)

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli

Lisa Gerner, Steffi Munack, Koen Temmerman, Ann-Marie Lawrence-Dörner et al. • Data in Brief (2016)

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) has been implicated in a range of conditions and pathologies from prostate to hepatic cancer. Here, we describe the expression in Escherichia coli and the purification protocol for the f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2016.06.033

Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt

Lotte B. Romijn, Axel A. Almet, Chin Wee Tan, James M. Osborne • BMC Bioinformatics (2020)

Abstract Background Many cancers arise from mutations in cells within epithelial tissues. Mutations manifesting at the subcellular level influence the structure and function of the tissue resulting in cancer. Previous work has proposed how ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12859-020-3391-3

Cross-cultural adaptation and psychometric properties of the Kessler Scale of Psychological Distress to a traumatic brain injury population in Swahili and the Tanzanian Setting

Joao Ricardo Nickenig Vissoci, Silvia Daniela Vaca, Deena El-Gabri, Leonardo Pestillo de Oliveira et al. • Health and Quality of Life Outcomes (2018)

Abstract Background To evaluate the psychometric properties of a Swahili version of the Kessler Psychological Distress scale in an injury population in Tanzania. Methods Swahili version of the Kessler Psychological Distress scale was develo...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-018-0973-0

An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement

Mhd Ayham Darwich, Katreen Ebrahem, Maysaa Shash, Hasan Mhd Nazha et al. • Applied Mechanics (2023)

This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving exist...

DOAJ Open Access (DOAJ) DOI: 10.3390/applmech4040063

Oxygen nanobubbles of ICG dimers achieve self-cascade photothermal and photodynamic therapy for hypoxia-reversible tumor treatment

Xiang Sun, Zheng Zhang, Moran Wang, Yuqin Chen et al. • Nano Research (2025)

Simultaneous photothermal and photodynamic therapies (PTT and PDT) hold great promise for noninvasive tumor therapy. However, effective regulation of PTT and PDT with optimal synergistic effects remains a challenge. To date, there are only ...

DOAJ Open Access (DOAJ) DOI: 10.26599/NR.2025.94907281

The deep learning applications in IoT-based bio- and medical informatics: a systematic literature review

Zahra Amiri, Arash Heidari, Nima Jafari Navimipour, Mansour Esmaeilpour et al. • Neural Computing and Applications (2024)

Abstract Nowadays, machine learning (ML) has attained a high level of achievement in many contexts. Considering the significance of ML in medical and bioinformatics owing to its accuracy, many investigators discussed multiple solutions for ...

OPENALEX cc-by DOI: https://doi.org/10.1007/s00521-023-09366-3

Theory, Abstraction and Design in Medical Informatics

F. Martín, J Crespo, Holger Billhardt, Víctor Maojo • Methods of Information in Medicine (2002)

OBJECTIVE: To analyze the scientific and engineering components of Medical Informatics. A clear characterization of these components should be undertaken to categorize different areas of Medical Informatics and create a research agenda for ...

OPENALEX Open Access DOI: https://doi.org/10.1055/s-0038-1634312

Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial

D. Ontaneda, P. Sati, P. Raza, M. Kilbane et al. • NeuroImage: Clinical (2021)

The specificity and implementation of current MRI-based diagnostic criteria for multiple sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are eventually determined not to have the disease, with overrelianc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102834

Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors

Foley Kristie, Ip Edward, Avis Nancy E • Health and Quality of Life Outcomes (2006)

Abstract Background This paper evaluates psychometric properties of a recently developed measure focusing on the health-related quality of life (HRQL) of long-term cancer survivors, the Quality of Life in Adult Survivors scale (QLACS), in a...

DOAJ Open Access (DOAJ) DOI: 10.1186/1477-7525-4-92

Is a prostate cancer screening anxiety measure invariant across two different samples of age-appropriate men?

Linder Suzanne K, Swank Paul R, Vernon Sally W, Morgan Robert O et al. • BMC Medical Informatics and Decision Making (2012)

Abstract Background In order to explore the influence of anxiety on decision–making processes, valid anxiety measures are needed. We evaluated a prostate cancer screening (PCS) anxiety scale that measures anxiety related to the prostate–spe...

DOAJ Open Access (DOAJ) DOI: 10.1186/1472-6947-12-52

An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions

Hanumanth Srikanth Cheruvu, Xin Liu, Jeffrey E Grice, Michael S. Roberts • Data in Brief (2022)

The dataset represented in this article is referred to by the review article entitled “Topical drug delivery: history, percutaneous absorption, and product development” (MS Roberts et al., 2021) [1]. The dataset contains maximal flux (Jmax)...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2022.108242

Progress with Formalization in Medical Informatics?

A. A. F. van der Maas, A. J. ten Hoopen, Arthur H. M. ter Hofstede • Journal of the American Medical Informatics Association (2001)

The prevailing view of medical informatics as a primarily subservient discipline in health care is challenged. Developments in both general informatics and medical informatics are described to identify desirable properties of modeling langu...

OPENALEX Open Access DOI: https://doi.org/10.1136/jamia.2001.0080126 PMC: 134552

Identifying elemental genomic track types and representing them uniformly

Gundersen Sveinung, Kalaš Matúš, Abul Osman, Frigessi Arnoldo et al. • BMC Bioinformatics (2011)

Abstract Background With the recent advances and availability of various high-throughput sequencing technologies, data on many molecular aspects, such as gene regulation, chromatin dynamics, and the three-dimensional organization of DNA, ar...

DOAJ Open Access (DOAJ) DOI: 10.1186/1471-2105-12-494