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Academic Articles & Research Papers
Showing 20 of 881 academic articles
Natalia Andelova, Iveta Waczulikova, Lukas Kunstek, Ivan Talian et al. • Scientific Reports
(2022)
Abstract Myocardial compensatory mechanisms stimulated by reduced oxygen utilization caused by streptozotocin-induced diabetes mellitus (DM) and treated with dichloroacetate (DCA) are presumably associated with the regulation of mitochondri...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-022-20696-5
Takawira C Marufu, Jane Coad, Zaki Albelbisi, Tim Carter et al. • Digital Health
(2026)
Objective Children and young people (CYP) presenting in mental health crisis to acute paediatric settings represent a growing clinical and system-level challenge. These environments, primarily designed for physical healthcare, frequently la...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/20552076261431890
Patrick Leo, Hauke Kolster, Hartmut Koeppen, Jennifer Giltnane et al. • Journal of Pathology Informatics
(2026)
Whereas anti-PD-(L)1 therapies are widely used in cancer treatment, only a subset of patients achieve long-term survival. Companion diagnostics based on PD-L1 expression have limited predictive power for these therapies, motivating developm...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jpi.2026.100688
Thulasee Jose, Ivana T. Croghan, J. Taylor Hays, Darrell R. Schroeder et al. • Journal of Primary Care & Community Health
(2021)
This analysis tested the hypothesis that current e-cigarette use was associated with an increased risk of SARS-CoV-2 infection in patients seeking medical care. E-cigarette and conventional cigarette use were ascertained using a novel elect...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/21501327211024391
Kirsch, Robert F, Ajiboye, A Bolu, Miller, Jonathan P • Journal of Medical Internet Research
(2019)
Intracortical brain-machine interfaces are a promising technology for allowing people with chronic and severe neurological disorders that resulted in loss of function to potentially regain those functions through neuroprosthetic devices. Th...
DOAJ
Open Access (DOAJ)
DOI: 10.2196/16339
Anton P. Semenov, Rais I. Mendgaziev, Andrey S. Stoporev, Vladimir A. Istomin et al. • Data in Brief
(2022)
The temperatures and pressures of the three-phase equilibrium V-Lw-H (gas – aqueous solution – gas hydrate) were measured in the CO2 – H2O – dimethyl sulfoxide (DMSO) system at concentrations of organic solute in the aqueous phase up to 50 ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.dib.2022.108289
Mário João Fartaria, Tobias Kober, Cristina Granziera, Meritxell Bach Cuadra • NeuroImage: Clinical
(2019)
Purpose: The goals of this study were to assess the performance of a novel lesion segmentation tool for longitudinal analyses, as well as to validate the generated lesion progression map between two time points using conventional and non-co...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.nicl.2019.101938
Daigle Bernie J, Roh Min K, Petzold Linda R, Niemi Jarad • BMC Bioinformatics
(2012)
Abstract Background A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data i...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/1471-2105-13-68
Frédéric Mahé, Torbjørn Rognes, Christopher Quince, Colomban de Vargas et al. • PeerJ
(2015)
Previously we presented Swarm v1, a novel and open source amplicon clustering program that produced fine-scale molecular operational taxonomic units (OTUs), free of arbitrary global clustering thresholds and input-order dependency. Swarm v1...
DOAJ
Open Access (DOAJ)
DOI: 10.7717/peerj.1420
Fiza Singh, I-Wei Shu, Sheng-Hsiou Hsu, Peter Link et al. • NeuroImage: Clinical
(2020)
Schizophrenia is a debilitating mental disorder that is associated with cognitive deficits. Impairments in cognition occur early in the course of illness and are associated with poor functional outcome, but have been difficult to treat with...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.nicl.2020.102339
Jinnan Hu, Donald Freed, Hanying Feng, Hong Chen et al. • Frontiers in Bioinformatics
(2026)
BackgroundIntegrating short- and long-read sequencing technologies has become a promising approach for achieving accurate and comprehensive genomic analysis. Although short-read sequencing (Illumina, etc.) offers high base accuracy and cost...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fbinf.2025.1691056
Jonathan R. Nebeker, John F. Hurdle, Byron D. Bair • The Journals of Gerontology Series A
(2003)
With deference to Isaac Asimov's The Foundation, which is the inspiration for this series, we briefly describe the "present history" of medical informatics (the application of information technology in medicine) in geriatrics, and then proj...
OPENALEX
DOI: https://doi.org/10.1093/gerona/58.9.m820
Maryam Lotfi, Deena Jalal, Ahmed A. Sayed • BMC Bioinformatics
(2026)
Abstract Background While whole genome sequencing has become a cornerstone of antimicrobial resistance surveillance, the reconstruction of plasmid sequences from short-read data remains a challenge due to repetitive sequences and assembly f...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12859-026-06585-y
Yong-Mi Kim, Dursun Delen • Health Informatics Journal
(2016)
The objective of this research is to identify major subject areas of medical informatics and explore the time-variant changes therein. As such it can inform the field about where medical informatics research has been and where it is heading...
OPENALEX
DOI: https://doi.org/10.1177/1460458216678443
Stefan Hammer, Wei Wang, Sebastian Will, Yann Ponty • BMC Bioinformatics
(2019)
Abstract Background The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the ne...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12859-019-2784-7
Lanfranchi Gerolamo, Teslovich Tanya M, Chen Yi-Wen, Toppo Stefano et al. • BMC Bioinformatics
(2002)
Abstract Background We describe the development, validation, and use of a highly redundant 120,000 oligonucleotide microarray (MuscleChip) containing 4,601 probe sets representing 1,150 known genes expressed in muscle and 2,075 EST clusters...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/1471-2105-3-33
Dallery, Jesse, Cassidy, Rachel N, Raiff, Bethany R • Journal of Medical Internet Research
(2013)
Technology-based interventions to promote health are expanding rapidly. Assessing the preliminary efficacy of these interventions can be achieved by employing single-case experiments (sometimes referred to as n-of-1 studies). Although singl...
DOAJ
Open Access (DOAJ)
DOI: 10.2196/jmir.2227
A. Arbiol-Roca, A. Padró-Miquel, M. Hueso, E. Navarro et al. • Data in Brief
(2017)
A long non-coding RNA called ANRIL located on chromosome 9p21.3 has been identified as a novel genetic factor associated with cardiovascular disease. Investigation of several single nucleotide polymorphisms (SNPs) of Noncoding Antisense RNA...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.dib.2017.02.011
Devika A Shenoy, Kathryn Radulovacki, Christian Zirbes, Rachelle Shao et al. • BMJ Open Quality
(2025)
Introduction Paediatric patients with elevated healthcare needs have limited access to care, contributing to insufficient preventive services. Social drivers of health (SDOH), such as inadequate nutrition and poor community support, contrib...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjoq-2025-003454
Shirley M. Coyle, King‐Tong Lau, Niall M. Moyna, Donal J. O’Gorman et al. • IEEE Transactions on Information Technology in Biomedicine
(2010)
Textile-based sensors offer an unobtrusive method of continually monitoring physiological parameters during daily activities. Chemical analysis of body fluids, noninvasively, is a novel and exciting area of personalized wearable healthcare ...
OPENALEX
Open Access
DOI: https://doi.org/10.1109/titb.2009.2038484