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A Novel Peptide Antibiotic Produced by Streptomyces roseoflavus Strain INA-Ac-5812 With Directed Activity Against Gram-Positive Bacteria

Alexey S. Vasilchenko, William T. Julian, Olda A. Lapchinskaya, Genrikh S. Katrukha et al. • Frontiers in Microbiology (2020)

In this work, we report the isolation and detailed functional characterization for the new non-ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of Streptomyces roseoflavus INA-Ac-5812. According to its chemica...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2020.556063

Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model

Zhen Li, Yannik Gehlen, Yannik Gehlen, Fabian Heizmann et al. • Frontiers in Bioengineering and Biotechnology (2020)

Discogenic low back pain (LBP) is a main cause of disability and inflammation is presumed to be a major driver of symptomatic intervertebral disc degeneration (IDD). Anti-inflammatory agents are currently under investigation as they demonst...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2020.00583

Ion Mobility Mass Spectrometry Reveals Rare Sialylated Glycosphingolipid Structures in Human Cerebrospinal Fluid

Mirela Sarbu, Dragana Fabris, Željka Vukelić, David E. Clemmer et al. • Molecules (2022)

Gangliosides (GGs) represent an important class of biomolecules associated with the central nervous system (CNS). In view of their special role at a CNS level, GGs are valuable diagnostic markers and prospective therapeutic agents. By ion m...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27030743

A novel sandwich ELISA method for quantifying CHI3L1 in blood serum and cerebrospinal fluid multiple sclerosis patients using sustainable photo-irradiated zero-valence gold nanoparticles

Marwa Saad Mohammed, Salwa H.N. Al-Rubaeꞌi, Ahmed Mahdi Rheima, Fatin Fadhel Al-Kazazz • Results in Chemistry (2024)

The widespread occurrence of chronic demyelinating MS presents a significant challenge for ongoing research aimed at comprehending its progression, diagnosis, and treatment. In our research, we have devised a novel approach to quantify CHI3...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rechem.2024.101856

β-D-galactopyranoside Seco-phytoporphyrin from Atropa Belladonna and Solanum Tuberosum Yellow Leaves Determined by Nuclear Magnetic Resonance

Nina Djapic • Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry (2021)

The study described the isolation of β-D-galactopyranoside seco-phytoporphyrin from Atropa belladonna and Solanum tuberosum yellow leaves. Column chromatography was applied for its isolation. The UV-Vis, mass spectrometry and NMR spectrosco...

DOAJ Open Access (DOAJ) DOI: 10.19261/cjm.2021.861

Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane

Abbirami Balachandran, Sy Bing Choi, Morak-Młodawska Beata, Jeleń Małgorzata et al. • Molecules (2023)

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral vascular disea...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031043

Antibiogram Profile and Resistance Patterns of Microflora from Vaginal Discharge in Reproductive-age Women at a Nigerian Teaching Hospital

Chizoba M. Enemchukwu, Christiana Nwabueze, Oluchi J. Osuala, Chinedu J. Ikem et al. • RADS Journal of Biological Research & Applied Science (2024)

Background: The adult human vagina hosts a complex biota containing diverse communities of microorganisms. The occurrence of multi-drug-resistant strains of these microorganisms has persistently increased due to poor hygiene and misuse or a...

DOAJ Open Access (DOAJ)

The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology

Jean-Étienne R. L. Morlighem, Chen Huang, Qiwen Liao, Paula Braga Gomes et al. • Marine Drugs (2018)

Marine invertebrates, such as sponges, tunicates and cnidarians (zoantharians and scleractinian corals), form functional assemblages, known as holobionts, with numerous microbes. This type of species-specific symbiotic association can be a ...

DOAJ Open Access (DOAJ) DOI: 10.3390/md16060207

Interactions of cephalexin with bovine serum albumin: displacement reaction and molecular docking

Hamed Hamishehkar, Soheila Hosseini, Abdolhossein Naseri, Azam Safarnejad et al. • BioImpacts (2016)

Introduction: The drug-plasma protein interaction is a fundamental issue in guessing and checking the serious drug side effects related with other drugs. The purpose of this research was to study the interaction of cephalexin with bovine se...

DOAJ Open Access (DOAJ) DOI: 10.15171/bi.2016.19

Crystal structure and Hirshfeld surface analysis of 4-allyl-2-methoxy-6-nitrophenol

Yassine El Ghallab, Sanae Derfoufi, El Mostafa Ketatni, Mohamed Saadi et al. • Acta Crystallographica Section E: Crystallographic Communications (2020)

The asymmetric unit of the title compound, C10H11NO4, which was synthesized via nitration reaction of eugenol (4-allyl-2-methoxyphenol) with a mixture of nitric acid and sulfuric acid, consists of three independent molecules of similar geom...

DOAJ Open Access (DOAJ) DOI: 10.1107/S2056989020002601

Injectable hyaluronic acid-collagen derived hydrogel based on component biomimetic as vitreous substitute

Shuo Wang, Jinhua Chi, Yanting Wang, Ruibao Ju et al. • Materials & Design (2026)

Vitrectomy is a common clinical treatment for fundus disease. Due to the non-renewable nature of the vitreous, artificial vitreous are usually required to replace natural vitreous to perform functions post operation. Silicone oil and gas, a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.matdes.2026.115780

In vivo and in vitro toxicity of nanogold conjugated snake venom protein toxin GNP-NKCT1

Partha Pratim Saha, Tanmoy Bhowmik, Anjan Kumar Dasgupta, Antony Gomes • Toxicology Reports (2014)

Research on nanoparticles has created interest among the biomedical scientists. Nanoparticle conjugation aims to target drug delivery, increase drug efficacy and imaging for better diagnosis. Toxicity profile of the nanoconjugated molecules...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2014.04.007

Advances in Astrophysics

• Advances in Astrophysics (2021)

Astrophysics is the branch of astronomy that employs the principles of physics and chemistry to ascertain the nature of the heavenly bodies, rather than their positions or motions in space. Among the objects studied are the Sun, other s...

OPENALEX Open Access DOI: https://doi.org/10.22606/adap

A search for $t\bar{t}$ resonances with the ATLAS detector in 2.05 fb−1 of proton-proton collisions at $\sqrt{s} = 7~\mathrm{TeV}$

The ATLAS Collaboration, G. Aad, B. Abbott, J. Abdallah et al. • European Physical Journal C: Particles and Fields (2012)

Abstract A search for top quark pair resonances in final states containing at least one electron or muon has been performed with the ATLAS experiment at the CERN Large Hadron Collider. The search uses a data sample corresponding to an integ...

DOAJ Open Access (DOAJ) DOI: 10.1140/epjc/s10052-012-2083-1

Veterinary Epidemiology

B CHOMEL • Sage eBooks (2008)

The author describes the specifics of veterinary epidemiology, in particular its domain and objectives. The large diversity of data sources are partly limited by the lack of standardized nomenclature and registries in many animal species. E...

OPENALEX Open Access DOI: https://doi.org/10.4135/9781412953948.n475

The M235T polymorphism in the angiotensinogen gene is not a major risk factor for diabetic nephropathy; a meta-analysis

Bhuneshwar Sahu, Shashikant Swarnakar, Henu Kumar Verma, Thavanati Parvathi Kumara Reddy et al. • Journal of Preventive Epidemiology (2022)

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in diabetes patients. The angiotensin AGT M235T gene polymorphism, which is linked to the renin-angiotensin-aldosterone system (RAAS), has been extensive...

DOAJ Open Access (DOAJ) DOI: 10.34172/jpe.2022.15

Metabolic perturbations underlying the associations of endocrine-disrupting chemical mixtures with muscle mass and strength in adults: A repeated-measures study

Kun Huang, Shuoshuo Hu, Yilin Zhou, Qingqing Cao et al. • Environmental Chemistry and Ecotoxicology (2025)

Introduction: Adult exposure to endocrine-disrupting chemicals (EDCs) may reduce muscle mass and strength; however, few studies considered EDC mixtures and their potential mechanisms. Objectives: We aimed to explore associations of EDC mixt...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.enceco.2025.08.019

Polyoxometalates in Medicine

Jeffrey T. Rhule, Craig L. Hill, Deborah A. Judd, Raymond F. Schinazi • Chemical Reviews (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolyoxometalates in MedicineJeffrey T. Rhule, Craig L. Hill, Deborah A. Judd, and Raymond F. SchinaziView Author Information Department of Chemistry, Emory University, Atlanta, Georgia 30322 Veter...

OPENALEX DOI: https://doi.org/10.1021/cr960396q

Soft Robotics

George M. Whitesides • Angewandte Chemie International Edition (2018)

This description of "soft robotics" is not intended to be a conventional review, in the sense of a comprehensive technical summary of a developing field. Rather, its objective is to describe soft robotics as a new field-one that offers oppo...

OPENALEX Open Access DOI: https://doi.org/10.1002/anie.201800907