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Academic Articles & Research Papers
Showing 20 of 49 academic articles
Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes
(2021)
Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/membranes11110847
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика
(2025)
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...
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Open Access (DOAJ)
DOI: 10.17749/2070-4909/farmakoekonomika.2024.285
Keisuke Hitachi, Masahiko Honda, Kunihiro Tsuchida • Cells
(2022)
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condit...
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Open Access (DOAJ)
DOI: 10.3390/cells11152291
Jun-Xue Jin, Jing-Tao Sun, Chao-Qian Jiang, Hong-Di Cui et al. • Antioxidants
(2022)
Previous studies suggest that the inclusion of melatonin (MTn) in in vitro maturation protocols improves the developmental competence of oocytes by scavenging reactive oxygen species (ROS). However, the molecular mechanisms integrating mela...
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Open Access (DOAJ)
DOI: 10.3390/antiox11040687
Zhanming Hou, Chaoyang Xue, Youliang Peng, Talma Katan et al. • Molecular Plant-Microbe Interactions
(2002)
Fusarium graminearum is an important pathogen of small grains and maize in many areas of the world. Infected grains are often contaminated with mycotoxins harmful to humans and animals. During the past decade, F. graminearum has caused seve...
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Open Access (DOAJ)
DOI: 10.1094/MPMI.2002.15.11.1119
Alexandra Kerbl, José M. Martín-Durán, Katrine Worsaae, Andreas Hejnol • EvoDevo
(2016)
Abstract Background Annelida is a morphologically diverse animal group that exhibits a remarkable variety in nervous system architecture (e.g., number and location of longitudinal cords, architecture of the brain). Despite this heterogeneit...
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Open Access (DOAJ)
DOI: 10.1186/s13227-016-0058-2
Cornelia Geßner, Alena Krüger, Lars P. Folkow, Wilfrid Fehrle et al. • Frontiers in Molecular Neuroscience
(2022)
The mammalian brain is characterized by high energy expenditure and small energy reserves, making it dependent on continuous vascular oxygen and nutritional supply. The brain is therefore extremely vulnerable to hypoxia. While neurons of mo...
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Open Access (DOAJ)
DOI: 10.3389/fnmol.2022.877349
Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience
(2026)
ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...
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Open Access (DOAJ)
DOI: 10.3389/fnins.2026.1783807
Graciela Gavia-García, David Hernández-Álvarez, Taide Laurita Arista-Ugalde, Itzen Aguiñiga-Sánchez et al. • Molecules
(2026)
Consumption of Sechium edule var. nigrum spinosum has antioxidant and hypoglycemic effects. Regarding the former, certain signaling pathways that influence these effects have already been proposed; however, the underlying molecular mechanis...
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Open Access (DOAJ)
DOI: 10.3390/molecules31071182
Angelo Vedani, Martin Smiesko, Morena Spreafico, Ourania Peristera et al. • ALTEX: Alternatives to Animal Experimentation
(2009)
The VirtualToxLab™ is an in silico tool for predicting the toxic (endocrine-disrupting) potential of drugs, chemicals and natural products. It is based on a fully automated protocol and calculates the binding affinity of any molecule of int...
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Open Access (DOAJ)
DOI: 10.14573/altex.2009.3.167
Zhongyang Du, Mengjing Liang, Xiaodan Wang, Yizhen Liu et al. • Journal of Advanced Research
(2026)
Introduction: Heavy metal pollution including lead (Pb) has become one of the serious global issues threatening food security, human health, and the ecosystem. Exogenous application of astaxanthin (ATX), a potent natural antioxidant, has be...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jare.2025.07.038
Sijie Li, Sijie Li, Changhong Ren, Changhong Ren et al. • Frontiers in Genetics
(2020)
Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...
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Open Access (DOAJ)
DOI: 10.3389/fgene.2020.582368
Zhong-Qi Bu, Hai-Yang Yu, Jue Wang, Xin He et al. • ASN Neuro
(2021)
Ischemic stroke is one of the main causes of high morbidity, mortality, and disability worldwide; however, the treatment methods are limited and do not always achieve satisfactory results. The pathogenesis of ischemic stroke is complex, def...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/17590914211037505
Kaixuan Chen, Longjun Chen, Yizhong Ma, Siqi Chen et al. • Frontiers in Pharmacology
(2025)
The skeletal system is an important support structure in the human body, and its homeostatic state is highly relevant to the development of a wide range of orthopaedic diseases. The search for key regulatory factors associated with skeletal...
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Open Access (DOAJ)
DOI: 10.3389/fphar.2025.1614542
Lusine Paronyan, Lilit Babayan, Haykuhi Vardanyan, Arsen Manucharyan et al. • Parasites & Vectors
(2024)
Abstract Background Armenia is considered particularly vulnerable to life-threatening vector-borne diseases (VBDs) including malaria, West Nile virus disease and leishmaniasis. However, information relevant for the control of the vectors of...
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Open Access (DOAJ)
DOI: 10.1186/s13071-024-06139-2
Noyonika Mukherjee, Li Lin, Christopher J. Contreras, Andrew T. Templin • Metabolites
(2021)
β-cell death is regarded as a major event driving loss of insulin secretion and hyperglycemia in both type 1 and type 2 diabetes mellitus. In this review, we explore past, present, and potential future advances in our understanding of the m...
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Open Access (DOAJ)
DOI: 10.3390/metabo11110796
Haiyan Yang, Ming Sun, Shuangji Lin, Yanhong Guo et al. • PLoS ONE
(2017)
Soil salinization is becoming a limitation to the utilization of ornamental plants worldwide. Crossostephium chinensis (Linnaeus) Makino is often cultivated along the southeast coast of China for its desirable ornamental qualities and high ...
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Open Access (DOAJ)
DOI: 10.1371/journal.pone.0187124
Scuderi SA, Basilotta R, Cucinotta L, Ardizzone A et al. • Journal of Inflammation Research
(2026)
Sarah Adriana Scuderi,1 Rossella Basilotta,2 Laura Cucinotta,2 Alessio Ardizzone,3 Emanuela Esposito21Genetics and Pharmacogenetics Unit, ‘Gaetano Martino’ University Hospital, Messina, Italy; 2Department of Chemical, Biological, Pharmaceut...
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Open Access (DOAJ)
Chun-Hua Wang, Lu-Kai Wang, Fu-Ming Tsai • Current Issues in Molecular Biology
(2025)
Tazarotene, a retinoid derivative, is widely used in treating skin conditions such as psoriasis and acne. Recent studies have demonstrated its potential as a promising therapeutic agent for treating melanoma in situ. Its primary mechanism o...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb47040237
Ella A. Zuiderwijk-Sick, Céline van der Putten, Raissa Timmerman, Jennifer Veth et al. • Frontiers in Immunology
(2021)
Interleukin (IL)-4 is a cytokine that affects both adaptive and innate immune responses. In the central nervous system, microglia express IL-4 receptors and it has been described that IL-4-exposed microglia acquire anti-inflammatory propert...
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Open Access (DOAJ)
DOI: 10.3389/fimmu.2021.771453