Academic Articles & Research Papers

A Predictive Model Based on the Gut Microbiota Improves the Diagnostic Effect in Patients With Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a malignant hepatic tumor with a poor prognosis, which needs early diagnosis urgently. The gut microbiota has been shown to play a crucial role in the progression of liver cancer. Here, we explored a gut microbio...

The human lung microbiome progressively diminishes in the distal alveolar regions

Abstract Extensive investigations with sequencing methods demonstrate a large and diverse microbiome even in profound areas of the lung. However, there is still substantial lack of cultivation-based evidence and of the viability of the resi...

Classical Biological Control of Invasive Legacy Crop Pests: New Technologies Offer Opportunities to Revisit Old Pest Problems in Perennial Tree Crops

Advances in scientific disciplines that support classical biological control have provided “new tools” that could have important applications for biocontrol programs for some long-established invasive arthropod pests. We suggest that these ...

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Abstract Background Gastric Cancer (GC) is the fourth most deadly cancer worldwide. Enhanced understanding of its key epidemiological and molecular drivers is urgently needed to lower the incidence and improve outcomes. Furthermore, tumor b...

Saccharomyces boulardii RC009 as an alternative to prophylactic antibiotics: effects on broiler chickens, performance, and gut microbiome

This study evaluates the effects of supplementing broiler chicken feed with the probiotic Saccharomyces cerevisiae var. boulardii RC009 as a sustainable alternative to prophylactic antibiotics. The focus was on productive performance, gut m...

Nano-enabled microbial bioinputs for sustainable agriculture: advances, mechanisms, applications, and future challenges

Microbial bioinputs have emerged as key components of sustainable agriculture owing to their ability to promote plant growth, improve nutrient acquisition, enhance tolerance to biotic and abiotic stresses, and suppress phytopathogens. Despi...

Establishment of Biocontrol Agents and Their Impact on Rhizosphere Microbiome and Induced Grapevine Defenses Are Highly Soil-Dependent

With a reduction in available chemical treatments, there is an increased interest in biological control of grapevine trunk diseases. Few studies have investigated the impact of introducing beneficial microorganisms in the rhizosphere on the...

Effects of Lactobacillus crispatus-Containing Probiotics and Metformin on Insulin Resistance, Inflammation, and Gut Microbiome in Polycystic Ovary Syndrome: Protocol for an Open-Label Randomized Controlled Trial.

Biogeographic Barriers and Gut Microbiome Turnover Across the Peromyscus maniculatus Species Complex.

Machine learning and deep learning applications in microbiome research

The many microbial communities around us form interactive and dynamic ecosystems called microbiomes. Though concealed from the naked eye, microbiomes govern and influence macroscopic systems including human health, plant resilience, and bio...

Microbiome-derived queuine vitamers underlie tyrosine metabolism and predator avoidance in mosquito larvae.

Genome-resolved discovery of Candidatus Vitaminotrophota reveals carbon fixation and multi-vitamin biosynthetic potential in hot springs.

Towards personalized and lifestyle-inspired soil management: lessons from the gut microbiome.

The Microbiome Composition of a Man's Penis Predicts Incident Bacterial Vaginosis in His Female Sex Partner With High Accuracy

Background: We determined the predictive accuracy of penile bacteria for incident BV in female sex partners. In this prospective cohort, we enrolled Kenyan men aged 18–35 and their female sex partners aged 16 and older. We assessed BV at ba...

CViewer: a Java-based statistical framework for integration of shotgun metagenomics with other omics datasets

Abstract Background Shotgun metagenomics for microbial community survey recovers enormous amount of information for microbial genomes that include their abundances, taxonomic, and phylogenetic information, as well as their genomic makeup, t...

Toward disease-associated fecal microbiome signatures for domestic mammals.

Gut Microbiome in Depression with and without REM Sleep Behavior Disorder.

Directional Gaussian Mixture Models of the Gut Microbiome Elucidate Microbial Spatial Structure

ABSTRACT The gut microbiome is spatially heterogeneous, with environmental niches contributing to the distribution and composition of microbial populations. A recently developed mapping technology, MaPS-seq, aims to characterize the spatial...

Pancreatic Islet Cell Hormones: Secretion, Function, and Diabetes Therapy

ABSTRACT The pancreatic islets of Langerhans, which are composed of α, β, δ, ε, and PP cells, orchestrate systemic glucose homeostasis through tightly regulated hormone secretion. Although the precise mechanisms involving β cells in the ons...

Precision Periodontics: Reimagining Periodontal Care through Precision Diagnostics and Targeted Therapies

Periodontitis is a chronic inflammatory disease that affects the tissues supporting teeth and represents a significant global health issue. Traditional diagnostic and treatment methods often use a broad approach and fall short due to the co...