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Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review

Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino et al. • International Journal for Equity in Health (2025)

Abstract Introduction Humanitarian crises exacerbate the vulnerability of already fragile healthcare systems and significantly increase the risk of infectious disease outbreaks in low- and middle-income countries (LMICs). This systematic re...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-025-02382-w

Impact of Pressurized Liquid Extraction and pH on Protein Yield, Changes in Molecular Size Distribution and Antioxidant Compounds Recovery from Spirulina

Jianjun Zhou, Min Wang, Celia Carrillo, Zhenzhou Zhu et al. • Foods (2021)

The research aims to extract nutrients and bioactive compounds from spirulina using a non-toxic, environmentally friendly and efficient method—Pressurized Liquid Extraction (PLE). In this work, Response Surface Methodology (RSM)–Central Com...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10092153

Autism Spectrum Disorder and collective catering service: results of the pilot study FOOD-AUT

Maria Vittoria Conti, Sara Santero, Chiara Breda, Sara Basilico et al. • Frontiers in Nutrition (2024)

ObjectiveIndividuals with Autism Spectrum Disorder (ASD) often exhibit a low dietary diversity due to food selectivity that leads them to a marked preference for high-energy-density food, exposing them to risk of malnutrition. Despite these...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2023.1298469

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Hospitalisations for physical abuse in infants and children less than 5 years, 2013‒2021: a multinational cohort study using administrative data from five European countries

Catherine Quantin, Jonathan Cottenet, Colleen Chambers, Natasha Kennedy et al. • International Journal of Population Data Science (2025)

Objectives Child physical abuse (CPA) is a global public health problem associated with lifelong negative consequences, yet reliable epidemiologic data are lacking. We did a multinational cohort study to analyse trends in CPA hospitalisatio...

DOAJ Open Access (DOAJ) DOI: 10.23889/ijpds.v10i3.3028

Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

Xinyi Wei, Yanding Su, Qian Cheng, Songmao Liang et al. • Frontiers in Pharmacology (2024)

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beag...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2024.1334402

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

Chuan Wang, Qian Wang, Guangming Xu, Guangming Xu et al. • Frontiers in Molecular Neuroscience (2024)

Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly a...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2024.1381098

Reimbursement Legislations and Decision Making for Orphan Drugs in Central and Eastern European Countries

Krzysztof Piotr Malinowski, Paweł Kawalec, Wojciech Trąbka, Marcin Czech et al. • Frontiers in Pharmacology (2019)

BackgroundReimbursement policies influence access of patients to orphan drugs in the European countries.ObjectivesTo provide a comprehensive description of orphan drug reimbursement policies and to assess reimbursement decision-making proce...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.00487

Medical biotechnology

Firdos Alam Khan • CRC Press eBooks (2018)

This chapter explains the role of biotechnology in medicine and explores the process of making antibodies and hybridoma technology. It shows how vaccines are manufactured and discusses the significance of stem cell therapy and the related i...

OPENALEX DOI: https://doi.org/10.1201/9781315370767-9

Effect of Adherence to the Mediterranean Diet on Maternal Iron Related Biochemical Parameters during Pregnancy and Gestational Weight Gain

María Morales-Suárez-Varela, Isabel Peraita-Costa, Alfredo Perales-Marín, Beatriz Marcos Puig et al. • Life (2023)

Gestation is a crucial life stage for both women and offspring, and outcomes are affected by many environmental factors, including diet. The Mediterranean dietary pattern (MD) is considered a healthy eating pattern that can provide the nutr...

DOAJ Open Access (DOAJ) DOI: 10.3390/life13051138

The human lung microbiome progressively diminishes in the distal alveolar regions

Pauline Potratz, Antje Häder, Laura Kursawe, Judith Kikhney et al. • npj Biofilms and Microbiomes (2026)

Abstract Extensive investigations with sequencing methods demonstrate a large and diverse microbiome even in profound areas of the lung. However, there is still substantial lack of cultivation-based evidence and of the viability of the resi...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41522-026-01047-y

Decision-Making Within Forensic Psychiatric Investigations: The Use of Various Information Sources by Different Expert Groups to Reach Conclusions on Legal Insanity

Lizel Göranson, Olof Svensson, Olof Svensson, Peter Andiné et al. • Frontiers in Psychiatry (2022)

BackgroundWhich type of information experts use to make decisions regarding legal insanity within forensic psychiatric investigations (FPI) is relatively unknown, both in general and when considering variations due to case context. It is im...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2022.822519

Automatic Identification of Brain Injury Mechanism Based on Deep Learning

YANG Qi-fan, SUN Xue-yang, WANG Yan-bin, TIAN Zhi-ling et al. • Fayixue Zazhi (2022)

ObjectiveTo apply the convolutional neural network (CNN) Inception_v3 model in automatic identification of acceleration and deceleration injury based on CT images of brain, and to explore the application prospect of deep learning technology...

DOAJ Open Access (DOAJ) DOI: 10.12116/j.issn.1004-5619.2021.410923