Academic Articles & Research Papers

Alterations in Hip and Knee Joint Contact Force Waveforms and Orientation Induced by Gait Modifications: A Case Study

Introduction & Purpose Idiopathic torsional deformities of lower limb bones can affect a patient’s gait pattern and joint health, while their cause remains unidentified (Koller et al., 2026). Abnormal joint loadings and the progression of ...

Breast Cancer and miR-SNPs: The Importance of miR Germ-Line Genetics

Recent studies in cancer diagnostics have identified microRNAs (miRNAs) as promising cancer biomarkers. Single nucleotide polymorphisms (SNPs) in miRNA binding sites, seed regions, and coding sequences can help predict breast cancer risk, a...

Genetic analysis of suicide: a sample study in Tuscany (Central Italy)

Many studies have examined the genetic contribution to suicide. However, data on suicide in the Italian population are scarce. We therefore aimed to address this gap by investigating a cohort of 111 Italians for whom a verdict of suicide ha...

A Mark-Release-Recapture Study to Estimate Field Performance of Imported Radio-Sterilized Male Aedes albopictus in Albania

The pathogen transmitting Aedes albopictus mosquito is spreading rapidly in Europe, putting millions of humans and animals at risk. This species is well-established in Albania since its first detection in 1979. The sterile insect technique ...

SveDem, the Swedish Dementia Registry - a tool for improving the quality of diagnostics, treatment and care of dementia patients in clinical practice.

BackgroundThe Swedish Dementia Registry (SveDem) was developed with the aim to improve the quality of diagnostic work-up, treatment and care of patients with dementia disorders in Sweden.MethodsSveDem is an internet based quality registry w...

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...

A Familial Case of Multiple Endocrine Neoplasia 2A: From Morphology to Genetic Alterations Penetration in Three Generations of a Family

This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) ...

Highly Sensitive and Specific Detection of Influenza A Viruses Using Bimolecular Fluorescence Complementation (BiFC) Reporter System

In this study, we developed a highly sensitive and specific bimolecular fluorescence complementation (BiFC)-based influenza A virus (IAV)-sensing system by combining a galactose/glucose-binding protein (GGBP) with an N-terminal large domain...

Nanotechnology in clinical laboratory diagnostics

Diagnostic innovations in Equine Parasitology: a Nanogold-ELISA for sensitive serodiagnosis of migratory strongylus vulgaris larvae infections

Abstract Strongylus vulgaris, a devastating parasitic nematode in equids, causes life-threatening verminous aneurysms that are challenging to diagnose early. This study pioneered integrating nanotechnology into an indirect enzyme-linked imm...

Potential Applications of Nanotechnology for the Diagnosis and Treatment of Pancreatic Cancer

Despite improvements in our understanding of pancreatic cancer and the emerging concept of personalized medicine for the treatment of this disease, it is still the fourth most common cause of cancer death in the western world. It is establi...

Nanotechnology in dentistry

Nanotechnology is manipulating matter at nanometer level and the application of the same to medicine is called nanomedicine. Nanotechnology holds promise for advanced diagnostics, targeted drug delivery, and biosensors. In the long-term, me...

Nanotechnology and Cancer

The biological picture of cancer is rapidly advancing from models built from phenomenological descriptions to network models derived from systems biology, which can capture the evolving pathophysiology of the disease at the molecular level....

MiRNA Profiles in Lymphoblastoid Cell Lines of Finnish Prostate Cancer Families.

BACKGROUND:Heritable factors are evidently involved in prostate cancer (PrCa) carcinogenesis, but currently, genetic markers are not routinely used in screening or diagnostics of the disease. More precise information is needed for making tr...

Advances in Imaging and Physiology-Guided Personalized Care in Acute Respiratory Distress Syndrome

Acute respiratory distress syndrome (ARDS) is a heterogeneous inflammatory lung injury marked by increased alveolar–capillary permeability, reduced respiratory system compliance, and impaired gas exchange. Despite advances in supportive car...

Robustness analysis of a Continuous-Time Markov Jump Process model for herd behaviour under stochastic shocks

Herd behaviour in socio-economic systems is characterised by asynchronous, stochastic decision-making that traditional models capture imperfectly. Discrete-time DTMCs impose fixed-tick synchrony and require binning, which distorts event tim...

A robust and uncertainty-aware machine learning framework for PM2.5 prediction in a coastal urban Indian environment: implications for sustainable air quality management

Abstract Accurate prediction of fine particulate matter (PM2.5) remains challenging because atmospheric processes are nonlinear, nonstationary, and influenced by temporal variability, measurement uncertainty, and episodic pollution events. ...

On-board diagnostics method for detecting bearing defects in traction synchronous permanent magnet motors based on stator current spectrum

Introduction. The reliability of traction electric drive is a key factor determining the operational efficiency of urban electric transport. Bearing assemblies of electric motors remain one of the most common causes of failures leading to v...

METHOD OF CONVERSATION IN PSYCHODIAGNOSTICS BY PROJECTIVE METHODS IN WORKING WITH STUDENTS OF NAUTICAL SPECIALTIES

Efficient electrochemical determination of dopamine in the presence of uric acid in real samples using tungsten disulfide nanostructure modified electrode

Background and purpose: Research on the detection of uric acid (URA) and dopamine (DPA) is ongoing because of the difficulties posed by their closely overlapping oxidation potentials. Tungsten disulfide nanostructures have become attractive...