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Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents

Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology (2022)

Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-022-03753-7

Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing

Ali Aytac Seymen, Ezgi Gulten, Erol Ozgur, Bülend Ortaç et al. • Scientific Reports (2023)

Abstract Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The development of rapid antigen tests has contributed to easing the burden on ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-31177-8

Cranial ultrasonographic findings in newborns exposed to SARS-CoV-2: a single-centre cross-sectional analysis

Bruna Scalia, Marco Andrea Nicola Saporito, Laura Mauceri, Alessandro Valerio Saporito et al. • Italian Journal of Pediatrics (2024)

Abstract Background SARS-CoV-2’s potential consequences on the developing brain are still unknown. The aim of this study was to describe cranial ultrasonographic (cUS) findings in a population of newborns exposed to SARS-CoV-2 born at San M...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13052-024-01826-3

SARS-CoV-2 Omicron BA.2.75 Variant May Be Much More Infective than Preexisting Variants Based on In Silico Model

Aki Sugano, Yutaka Takaoka, Haruyuki Kataguchi, Mika Ohta et al. • Microorganisms (2022)

Previously, we developed a mathematical model via molecular simulation analysis to predict the infectivity of six SARS-CoV-2 variants. In this report, we aimed to predict the relative risk of the recent new variants of SARS-CoV-2 based on o...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms10102090

Seaweed-Derived Sulfated Polysaccharides as Potential Agents for Prevention and Treatment of Influenza and COVID-19

N. N. Besednova, T. N. Zvyagintseva, B. G. Andriukov, T. S. Zaporozhets et al. • Антибиотики и Химиотерапия (2021)

The review presents materials describing the seaweed-derived sulfated polysaccharides (SPS) as potential means for prevention and treatment of viral diseases of the respiratory tract, mainly influenza and COVID-19. The literature materials o...

DOAJ Open Access (DOAJ) DOI: 10.37489/0235-2990-2021-66-7-8-50-66

Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review

Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino et al. • International Journal for Equity in Health (2025)

Abstract Introduction Humanitarian crises exacerbate the vulnerability of already fragile healthcare systems and significantly increase the risk of infectious disease outbreaks in low- and middle-income countries (LMICs). This systematic re...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-025-02382-w

Case report: Incidentally discovered case of pheochromocytoma as a cause of long COVID-19 syndrome

Christian G. Ziegler, Carina Riediger, Matthias Gruber, Carola Kunath et al. • Frontiers in Endocrinology (2022)

Pheochromocytomas (PCCs) are rare but potentially lethal tumors that arise from the adrenal medulla. The clinical suspicion and diagnosis of PCC can be challenging due to the non-specific nature of signs and symptoms. In many patients, infe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2022.967995

What motivates SARS-CoV-2 vaccine trial participants? A pre- and post-participation survey study

Olivia A. C. Lamers, Meta Roestenberg, Martine C. de Vries, Marie-Astrid Hoogerwerf • Trials (2024)

Abstract Background Scientific advancement, including the testing and licensing of new drugs, relies heavily on clinical trials with healthy individuals. The motivations of clinical trial participants have been discussed intensively, as som...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13063-024-08582-z

An update on the impact of SARS-CoV-2 pandemic public awareness on cancer patients' COVID-19 vaccine compliance: Outcomes and recommendations

Lina Souan, Maher A. Sughayer, Maha Abu Alhowr, Khawlah Ammar et al. • Frontiers in Public Health (2022)

Background:Aside from the pandemic's negative health effects, the world was confronted with public confusion since proper communication and favorable decisions became an ongoing challenge. As a result, the public's perceptions were influenc...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2022.923815

Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

Denise Battaglini, Denise Battaglini, Lavienraj Premraj, Lavienraj Premraj et al. • Frontiers in Medicine (2022)

IntroductionNeurological manifestations and complications in coronavirus disease-2019 (COVID-19) patients are frequent. Prior studies suggested a possible association between neurological complications and fatal outcome, as well as the exis...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.930217

Postbiotics: From emerging concept to application

Sunita Aggarwal, Vandana Sabharwal, Pragya Kaushik, Anushka Joshi et al. • Frontiers in Sustainable Food Systems (2022)

The microbiome innovation has resulted in an umbrella term, postbiotics, which refers to non-viable microbial cells, metabolic byproducts and their microbial components released after lysis. Postbiotics, modulate immune response, gene expre...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2022.887642

Age and Ageing During the COVID-19 Pandemic; Challenges to Public Health and to the Health of the Public

A. Mark Clarfield, A. Mark Clarfield, Tzvi Dwolatzky, Tzvi Dwolatzky • Frontiers in Public Health (2021)

The distribution of the SARS-CoV-2 virus has reached pandemic proportions. While COVID-19 can affect anyone, it is particularly hazardous for those with “co-morbidities.” Older age is an especially strong and independent risk factor for hos...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2021.655831

A 1-minute blood test detects decreased immune function and increased clinical risk in COVID-19 patients

Chirajyoti Deb, Allan N. Salinas, Tianyu Zheng, Aurea Middleton et al. • Scientific Reports (2021)

Abstract Upon infection with SARS-CoV-2, the virus that causes COVID-19, most people will develop no or mild symptoms. However, a small percentage of the population will become severely ill, and some will succumb to death. The clinical seve...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-02863-2

Is SARS-CoV-2 a concern in the largest wastewater treatment plant in middle east?

Hasan Pasalari, Angila Ataei-Pirkooh, Mitra Gholami, Iman Rezaei Azhar et al. • Heliyon (2023)

The surveillance of wastewater treatment plant (WWTP) as the end point of SARS-CoV-2 shed from infected people arise a speculation on transmission of this virus of concern from WWTP in epidemic period. To this end, the present study was dev...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2023.e16607

Electronic Cigarette Use Is Not Associated with COVID-19 Diagnosis

Thulasee Jose, Ivana T. Croghan, J. Taylor Hays, Darrell R. Schroeder et al. • Journal of Primary Care & Community Health (2021)

This analysis tested the hypothesis that current e-cigarette use was associated with an increased risk of SARS-CoV-2 infection in patients seeking medical care. E-cigarette and conventional cigarette use were ascertained using a novel elect...

DOAJ Open Access (DOAJ) DOI: 10.1177/21501327211024391

Lessons From a Rapid Project Management Exercise in the Time of Pandemic: Methodology for a Global COVID-19 VIRUS Registry Database

Janice R Turek, Vikas Bansal, Aysun Tekin, Shuchita Singh et al. • JMIR Research Protocols (2022)

BackgroundThe rapid emergence of the COVID-19 pandemic globally collapsed health care organizations worldwide. Incomplete knowledge of best practices, progression of disease, and its impact could result in fallible care. Data on symptoms an...

DOAJ Open Access (DOAJ) DOI: 10.2196/27921

Secondary research use of personal medical data: patient attitudes towards data donation

Gesine Richter, Christoph Borzikowsky, Bimba Franziska Hoyer, Matthias Laudes et al. • BMC Medical Ethics (2021)

Abstract Background The SARS-CoV-2 pandemic has highlighted once more the great need for comprehensive access to, and uncomplicated use of, pre-existing patient data for medical research. Enabling secondary research-use of patient-data is a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12910-021-00728-x

Noninvasive aspergillosis following COVID-19 exacerbates the severity of SARS-CoV-2 infection

Jong Seung Kim, Jun Hyung Park, Juhyun Kim, Yong Chul Lee et al. • International Journal of Infectious Diseases (2026)

Objectives: Few large-scale population-based studies have examined the association between COVID-19 and respiratory aspergillosis. Using nationwide data, we investigated whether SARS-CoV-2 infection increases respiratory aspergillosis incid...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijid.2026.109095

Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Kristoffer Strålin, Erik Wahlström, Sten Walther, Anna M Bennet-Bark et al. • The Lancet Regional Health. Europe (2021)

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.lanepe.2021.100054

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

Kejie Mou, Mohnad Abdalla, Dong Qing Wei, Muhammad Tahir Khan et al. • Informatics in Medicine Unlocked (2021)

Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one of the structural proteins; plays a critical role in v...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.imu.2021.100675