Academic Articles & Research Papers

A systematic review of worldwide epidemiology of psoriasis

To inform the WHO Global report on psoriasis, a new comprehensive worldwide systematic review of the epidemiology of psoriasis was undertaken. The aim of this study was to systematically review the worldwide literature regarding the epidemi...

Epidemiology of acne vulgaris

Despite acne being an almost universal condition in younger people, relatively little is known about its epidemiology. We sought to review what is known about the distribution and causes of acne by conducting a systematic review of relevant...

Psoriasis: epidemiology

Exploring Potential Therapeutic Applications of Tazarotene: Gene Regulation Mechanisms and Effects on Melanoma Cell Growth

Tazarotene, a retinoid derivative, is widely used in treating skin conditions such as psoriasis and acne. Recent studies have demonstrated its potential as a promising therapeutic agent for treating melanoma in situ. Its primary mechanism o...

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

Abstract Background Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid disease characterized by the early onset of age-related phenotypes including arthritis, loss of body fat and hair, and atherosclerosis. Cells from affected indiv...

The immunology of psoriasis

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

BackgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks. The pathogenesis of HS is not fully understood, bu...

Fundamental immunology

Topical Pharmacological Treatment of Actinic Keratoses: Focus on Tirbanibulin 1% Ointment

Actinic keratosis (AK) is a frequent precancerous skin lesion that mostly affects chronically sun-exposed areas. Chronic sun damage leads to various mutations in onco-suppressor and oncogenic genes which cause an uncontrolled proliferation ...

Deep-Learning based Melanoma Detection using Cloud Approach

The aim of computer vision techniquesand deep learning in the era of digitalization is to derive valuable insights from them and generate novel understanding. This makes it possible to employ imaging to quickly diagnose and treat a variety ...

Deep learning classification for macrophage subtypes through cell migratory pattern analysis

Macrophages can exhibit pro-inflammatory or pro-reparatory functions, contingent upon their specific activation state. This dynamic behavior empowers macrophages to engage in immune reactions and contribute to tissue homeostasis. Understand...

Deep learning-enabled medical computer vision

A decade of unprecedented progress in artificial intelligence (AI) has demonstrated the potential for many fields-including medicine-to benefit from the insights that AI techniques can extract from data. Here we survey recent progress in th...

Educational Artificial Intelligence Software to Support Assessment of Atopic Dermatitis Severity.

Influencing Factors Associated With Infantile Hemangioma: A Case-Control Study Among Chinese Pediatric Populations.

Artificial intelligence tools in dermatology education: A scoping review on their application, efficacy, and limitations

Introduction: Artificial Intelligence (AI) is increasingly explored for medical education, and dermatology, with its visual diagnostic focus, holds promise for AI-enhanced learning. However, evidence on its educational effectiveness remains...

Artificial Intelligence for Lentigo Maligna: Automated Margin Assessment via Sox-10-Based Melanocyte Density Mapping

Lentigo maligna (LM) is a melanoma in situ with high cumulative sun damage. Histological evaluation of resection margins is difficult and time-consuming. Melanocyte density (MD) is a suitable, quantifiable, and reproducible diagnostic crite...