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Immunoinformatics and Reverse Vaccinology Approach for the Identification of Potential Vaccine Candidates against <i>Vandammella animalimors</i>

Ahmad Hasan, Wadi B. Alonazi, Muhammad Ibrahim, Li Bin • Microorganisms (2024)

Vandammella animalimorsus is a Gram-negative and non-motile bacterium typically transmitted to humans through direct contact with the saliva of infected animals, primarily through biting, scratches, or licks on fractured skin. The absence o...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms12071270

Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration

Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open (2023)

Introduction Alzheimer’s disease and other dementias affect &gt;50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-077772

Idiopathic pulmonary fibrosis: Addressing the current and future therapeutic advances along with the role of Sotatercept in the management of pulmonary hypertension

Dalia D. Hadi, Mohammed Dheyaa Marsool Marsool, Ali Dheyaa Marsool Marsool, Neel Vora et al. • Immunity, Inflammation and Disease (2023)

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating lung disease characterized by irreversible scarring of the lungs. The cause of IPF is unknown, but it is thought to involve a combination of genetic a...

DOAJ Open Access (DOAJ) DOI: 10.1002/iid3.1079

Effects of an 8-week multimodal exercise program on ground reaction forces and plantar pressure during walking in boys with autism spectrum disorder

Mahrokh Dehghani, Amir Ali Jafarnezhadgero, Mohamad Abdollahpour Darvishani, Shirin Aali et al. • Trials (2023)

Abstract Background Autism spectrum disorder is a developmental disability with first signs appearing in children aged 3 years and younger. Given that autism spectrum disorder is accompanied by a broad range of symptoms such as impaired sen...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13063-023-07158-7

Polyphenols: From Theory to Practice

Alberto Bertelli, Marco Biagi, Maddalena Corsini, Giulia Baini et al. • Foods (2021)

Background: The importance of polyphenols in human health is well known; these compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and wine. On the other hand, the different factors that modulate the bi...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10112595

C no more: a prospective single-arm study to evaluate the effectiveness of a nurse and peer-led mobile model of hepatitis C testing and treatment at community corrections offices

Samara Griffin, Timothy Papaluca, Jacinta A Holmes, Bridget Reid et al. • Health & Justice (2026)

Abstract Background The community corrections population in Australia shares similar risk factors for hepatitis C virus (HCV) infection with people incarcerated in prisons, but without access to prison-based testing and treatment. While hep...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40352-026-00411-6

Identification of functional pathways for regenerative bioactivity of selected renal cells

Wei Sha, Timothy Bertram, Deepak Jain, Cory Brouwer et al. • Stem Cell Research & Therapy (2022)

Abstract Background Selected renal cells (SRC) are in Phase II clinical trials as a kidney-sourced, autologous, tubular epithelial cell-enriched cell-based therapy for chronic kidney disease (CKD). In preclinical studies with rodent models ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13287-022-02713-6

On Combined Maximal Precedence–Exceedance Test with Application to HIV Clinical Trials

Sylvester Sebola, Niladri Chakraborty, Morné Rowan Sjölander • Mathematics (2026)

This paper proposes a combined maximal precedence–exceedance test (MPErs) that integrates maximal precedence and maximal exceedance statistics tests to provide sensitivity to both early and late distributional differences between two sample...

DOAJ Open Access (DOAJ) DOI: 10.3390/math14203658

Barriers and opportunities for clinical trials in Bahrain: a qualitative study of key opinion leaders

Jamil Ahmed, Angeleena Esther, Hussein AlHafnawi, Mohamed Hany Shehata et al. • BMJ Open (2026)

Background and objectives Clinical trials are essential for advancing scientific knowledge and improving patient outcomes. In the last decade, Bahrain has made notable progress in healthcare. However, clinical trial participation from the r...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2026-117241

Identifying research particiaption effects through qualitative methods: Feedback from Research Engagement Consultants involved in a pediatric mental health comparative effectiveness trial

Elisabeth A. Stelson, Mallory Bolenbaugh, Briana Woods-Jaeger, Cassidy Branch et al. • SSM: Qualitative Research in Health (2021)

Research participation effects (RPEs)—effects due to study design rather than study intervention—have long been acknowledged as a research phenomenon. Identifying RPEs is crucial to understanding the true effects of an intervention and outc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ssmqr.2021.100023

Effectiveness of echocardiography and cardiac magnetic resonance for screening and monitoring cardiomyopathy in people living with HIV: a mixed-methods systematic review protocol

Flávia Figueira, Matheus de Sá Freitas Tavares, Carla Betina Andreucci, Bernardino Geraldo Alves Souto et al. • Systematic Reviews (2026)

Abstract Background People living with HIV (PLWH) have a markedly increased risk of cardiovascular disease (CVD), including cardiomyopathy, due to a complex interplay of chronic inflammation, viral persistence, and antiretroviral therapy (A...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13643-026-03091-3

Circulating tumour cell enumeration, biomarker analyses, and kinetics in patients with colorectal cancer and other GI malignancies

Walla Malkawi, Areeb Lutfi, Maaz Khan Afghan, Lamisha Mashiyat Shah et al. • Frontiers in Oncology (2023)

ObjectiveMost of the work in terms of liquid biopsies in patients with solid tumors is focused on circulating tumor DNA (ctDNA). Our aim was to evaluate the feasibility of using circulating tumor cells (CTCs) in peripheral blood samples fro...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2023.1305181

The influence of family in children’s feeding difficulties: an integrative review

Pâmela Gracielle da Fonseca, António Raposo, Nada Alqarawi, Ibrahim Alasqah et al. • Frontiers in Pediatrics (2025)

BackgroundFeeding difficulties, such as limited appetite, selective eating, and food phobia, affect caregivers' ability to provide adequate nutrition to children. These issues impact 25%–40% of non-neurodivergent children and up 80% of neur...

DOAJ Open Access (DOAJ) DOI: 10.3389/fped.2025.1609714

Efficacy of heel lifts versus calf muscle eccentric exercise for mid-portion Achilles tendinopathy (the HEALTHY trial): study protocol for a randomised trial

Chantel L. Rabusin, Hylton B. Menz, Jodie A. McClelland, Angela M. Evans et al. • Journal of Foot and Ankle Research (2019)

Abstract Background Mid-portion Achilles tendinopathy is a common musculoskeletal condition characterised by degeneration of the Achilles tendon, which causes pain and disability. Multiple non-surgical treatments have been advocated for thi...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13047-019-0325-2