Academic Articles & Research Papers

Serum Bilirubin Level Changes in Multiple Sclerosis Patients

Background: Multiple Sclerosis (MS) is a demyelinating disorder of the Central Nervous System (CNS). In addition to the role of immune mediated mechanisms, oxidative and nitrosative stress also play an important role in neuropathology of MS...

Reliable Parkinson’s Disease Detection by Analyzing Handwritten Drawings: Construction of an Unbiased Cascaded Learning System Based on Feature Selection and Adaptive Boosting Model

Parkinson's disease (PD) is the second most common neurodegenerative disease of central nervous system (CNS). Till now, there is no definitive clinical examination that can diagnose a PD patient. However, it has been reported that PD patien...

The transcription factor SoxD controls neuronal guidance in the Drosophila visual system

Abstract Precise control of neurite guidance during development is essential to ensure proper formation of neuronal networks and correct function of the central nervous system (CNS). How neuronal projections find their targets to generate a...

Artificial Neural Networks

An artificial neural network (ANN) is a functional abstraction of the biologic neural structures of the central nervous system (Aleksander and Morton 1993; Rudomin et al. 1993; Arbib 1995; Anderson 1995). It is essentially a simple mathemat...

A deep learning approach to predict blood-brain barrier permeability

The blood–brain barrier plays a crucial role in regulating the passage of 98% of the compounds that enter the central nervous system (CNS). Compounds with high permeability must be identified to enable the synthesis of brain medications for...

Effect of robot-assisted gait training combined with electroacupuncture on lower limb motor function and brain network characteristics in stroke: an EEG study

Abstract Background Stroke survivors often experience residual motor dysfunction in their limbs. Additional physical rehabilitation therapies may further improve patients’ functional outcomes. By combining direct interventions targeting the...

Validation of the "purfling sign" for differentiating primary central nervous system lymphoma from high-grade glioma: a retrospective multicenter cohort study.