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Physicochemical- and biocompatibility of oxygen and nitrogen plasma treatment using a PLA scaffold

Ali Davoodi, Homayoun H. Zadeh, Morteza Daliri Joupari, Mohammad Ali Sahebalzamani et al. • AIP Advances (2020)

Plasma surface treatment has a wide range of applications in biomedicine. In the present study, flat polylactic acid (PLA) films were treated with oxygen and nitrogen, low-pressure, non-thermal plasma. The water contact angle of the PLA fil...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0022306

Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane

Abbirami Balachandran, Sy Bing Choi, Morak-Młodawska Beata, Jeleń Małgorzata et al. • Molecules (2023)

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral vascular disea...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031043

Antibiogram Profile and Resistance Patterns of Microflora from Vaginal Discharge in Reproductive-age Women at a Nigerian Teaching Hospital

Chizoba M. Enemchukwu, Christiana Nwabueze, Oluchi J. Osuala, Chinedu J. Ikem et al. • RADS Journal of Biological Research & Applied Science (2024)

Background: The adult human vagina hosts a complex biota containing diverse communities of microorganisms. The occurrence of multi-drug-resistant strains of these microorganisms has persistently increased due to poor hygiene and misuse or a...

DOAJ Open Access (DOAJ)

The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology

Jean-Étienne R. L. Morlighem, Chen Huang, Qiwen Liao, Paula Braga Gomes et al. • Marine Drugs (2018)

Marine invertebrates, such as sponges, tunicates and cnidarians (zoantharians and scleractinian corals), form functional assemblages, known as holobionts, with numerous microbes. This type of species-specific symbiotic association can be a ...

DOAJ Open Access (DOAJ) DOI: 10.3390/md16060207

Interactions of cephalexin with bovine serum albumin: displacement reaction and molecular docking

Hamed Hamishehkar, Soheila Hosseini, Abdolhossein Naseri, Azam Safarnejad et al. • BioImpacts (2016)

Introduction: The drug-plasma protein interaction is a fundamental issue in guessing and checking the serious drug side effects related with other drugs. The purpose of this research was to study the interaction of cephalexin with bovine se...

DOAJ Open Access (DOAJ) DOI: 10.15171/bi.2016.19

Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer

Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher et al. • Molecular Cancer (2025)

Abstract The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-024-02221-6

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan et al. • Diagnostics (2018)

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been impl...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics8040079

Structure and transport mechanism of P5B-ATPases

Ping Li, Kaituo Wang, Nina Salustros, Christina Grønberg et al. • Nature Communications (2021)

In human cells, P5B‐ATPases execute export of spermine from lysosomes to the cytosol, but the mechanisms of spermine recognition, uptake and transport remain elusive. Here the authors present cryo‐EM structures of a yeast homolog of human A...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-24148-y

Emergence of Carbapenem-Resistant Enterobacteriaceae in a Tertiary Care Hospital in Southern Thailand†

Prerit Upadhyaya ARYAL, Benjamas THAMJARUNGWONG, Kamonnut SINGKHAMANAN, Paramee THONGSUKSAI et al. • Walailak Journal of Science and Technology (2020)

Carbapenem-resistant Enterobacteriaceae (CRE) is emerging as a major problem in healthcare settings globally, including Thailand, due to limited therapeutic options. We reported the detection, antimicrobial susceptibility profiles, and the ...

DOAJ Open Access (DOAJ)

Complex Abdominal Wall Hernias: Structured Use of Adjuvant Therapies

Joana Marques‐Antunes, Egon Rodrigues, Marta Guimarães, Marta Guimarães et al. • Journal of Abdominal Wall Surgery (2025)

PurposeRepairing complex abdominal wall hernias is challenging, often requiring component separation techniques (CST) for tension-free closure. Adjuvant therapies, such as botulinum toxin type A (BTA), preoperative progressive pneumoperiton...

DOAJ Open Access (DOAJ) DOI: 10.3389/jaws.2025.14515

Crystal structure and Hirshfeld surface analysis of 4-allyl-2-methoxy-6-nitrophenol

Yassine El Ghallab, Sanae Derfoufi, El Mostafa Ketatni, Mohamed Saadi et al. • Acta Crystallographica Section E: Crystallographic Communications (2020)

The asymmetric unit of the title compound, C10H11NO4, which was synthesized via nitration reaction of eugenol (4-allyl-2-methoxyphenol) with a mixture of nitric acid and sulfuric acid, consists of three independent molecules of similar geom...

DOAJ Open Access (DOAJ) DOI: 10.1107/S2056989020002601

Resting-state EEG measures cognitive impairment in Parkinson’s disease

Md Fahim Anjum, Arturo I. Espinoza, Rachel C. Cole, Arun Singh et al. • npj Parkinson's Disease (2024)

Abstract Cognitive dysfunction is common in Parkinson’s disease (PD). We developed and evaluated an EEG-based biomarker to index cognitive functions in PD from a few minutes of resting-state EEG. We hypothesized that synchronous changes in ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41531-023-00602-0

Flavanol-Rich Cocoa Supplementation Inhibits Mitochondrial Biogenesis Triggered by Exercise

Jose Angel García-Merino, Beatriz de Lucas, Karen Herrera-Rocha, Diego Moreno-Pérez et al. • Antioxidants (2022)

The potential role of cocoa supplementation in an exercise context remains unclear. We describe the effects of flavanol-rich cocoa supplementation during training on exercise performance and mitochondrial biogenesis. Forty-two male enduranc...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11081522

Housekeeping gene expression variability in differentiating and non-differentiating 3T3-L1 cells

Danang Dwi Cahyadi, Tomoko Warita, Nanami Irie, Kana Mizoguchi et al. • Adipocyte (2023)

ABSTRACTNormalization is a crucial step in gene expression analysis to avoid misinterpretation. Reverse transcription-quantitative polymerase chain reaction was used to measure the expression of 10 candidate housekeeping genes in non-differ...

DOAJ Open Access (DOAJ) DOI: 10.1080/21623945.2023.2235081

Injectable hyaluronic acid-collagen derived hydrogel based on component biomimetic as vitreous substitute

Shuo Wang, Jinhua Chi, Yanting Wang, Ruibao Ju et al. • Materials & Design (2026)

Vitrectomy is a common clinical treatment for fundus disease. Due to the non-renewable nature of the vitreous, artificial vitreous are usually required to replace natural vitreous to perform functions post operation. Silicone oil and gas, a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.matdes.2026.115780

ABCD: advanced blockchain DSR algorithm for MANET to mitigate the different security threats

Sayan Majumder, Debika Bhattacharyya, Swati Chowdhuri • EURASIP Journal on Wireless Communications and Networking (2025)

Abstract Mobile ad hoc networks (MANETs) facilitate data communication across multiple nodes and hop stations, characterized by their dynamic topology. This inherent flexibility, however, makes MANETs vulnerable to various security threats,...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13638-025-02430-7

Patient and Public Involvement Work With Parents of Children With Life‐Limiting Conditions and Bereaved Parents: A Rapid Systematic Review

Pru Holder, Bethan Page, Julia Hackett, Sarah Mitchell et al. • Health Expectations (2024)

ABSTRACT Background Guidance and principles for involving the public in research or service planning exist but are not specific to the needs of parents of children with life‐limiting conditions or bereaved parents. Aim Review the evidence o...

DOAJ Open Access (DOAJ) DOI: 10.1111/hex.70120