Academic Articles & Research Papers

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

Determination of Novel Estimations for the Slater Difference and Applications

The field of mathematical inequalities has exerted a profound influence across a multitude of scientific disciplines, making it a captivating and expansive domain ripe for research investigation. This article offers estimations for the Slat...

Novel fractional integral inequalities for GA-Cr-convex functions and connections with information systems

Due to applicability of mathematical inequalities in control systems, actuarial science, information theory and its utilization in other sciences, several researchers are inclined to prove their refinements and generalizations. In the study...

On the Moments and the Distribution of Aggregate Discounted Claims in a Markovian Environment

This paper studies the moments and the distribution of the aggregate discounted claims (ADCs) in a Markovian environment, where the claim arrivals, claim amounts, and forces of interest (for discounting) are influenced by an underlying Mark...

Empirical study on optimal reinsurance for crop insurance in China from an insurer's perspective

This study investigates the optimal reinsurance for crop insurance in China in an insurer's perspective using the data from Inner Mongolia, Jilin, and Liaoning, China. On the basis of the loss ratio distributions modeled by AnHua Crop Risk ...

Modelling the adsorption of iron and manganese by activated carbon from teak and shea charcoal for continuous low flow

Nearly 6494 boreholes with iron (Fe) and manganese (Mn) concentrations above permissible limits of 0.3 mg/L and 0.4 mg/L respectively in Ghana have been abandoned because of ineffective water treatment solutions. Activated carbon prepared f...

Beyond airborne spread: a dual-route Wells-Riley extension for estimating norovirus infection risk in Ghanaian pediatric wards

Background: The classic Wells–Riley model (CWRM) is a well-established framework for estimating airborne infection risk in shared indoor environments. This study extends the framework to simultaneously incorporate fecal–oral transmission, a...

Changes in the geographical distribution of youth poverty and social exclusion in EU member countries between 2008 and 2017

With respect to the fulfillment of the objectives of the Europe 2020 strategy, the threat of poverty and social exclusion has not been sufficiently reduced in the European Union (EU) over the past decade, and large regional disparities pers...

Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data

Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap, we conducted five studies usin...

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...

Robustness analysis of a Continuous-Time Markov Jump Process model for herd behaviour under stochastic shocks

Herd behaviour in socio-economic systems is characterised by asynchronous, stochastic decision-making that traditional models capture imperfectly. Discrete-time DTMCs impose fixed-tick synchrony and require binning, which distorts event tim...

Mathematical Modeling of Leptospirosis With Misdiagnosis

Leptospirosis is a widespread zoonotic bacterial disease that continues to pose a major public health challenge, particularly in developing countries where it causes substantial morbidity, mortality, and economic losses. A key problem in co...

Ozonation, electrochemical, and biological methods for the remediation of malachite green dye wastewaters: A mini review

The extensive usage of malachite green (MG) dyes in the fish and dye industries cause serious water pollution, leading to catastrophic effects on living organisms and the environment. In addressing the challenges of health risks related to ...

The risk of colorectal cancer according to obesity status at four-year intervals: a nationwide population-based cohort study

Abstract Obesity is a risk factor for colorectal cancer. However, the effect of body weight change on colorectal cancer is uncertain. This study aimed to investigate the relationship between difference in body mass index and the risk of col...

Darboux operators for linear first-order multi-component equations in arbitrary dimensions

Metabolomic sweet spot clock predicts mortality and age-related diseases in the Canadian Longitudinal Study on Aging

Abstract Background Chronological age does not capture individual health or resilience. Advances in metabolomics have enabled development of molecular aging biomarkers that capture deviations between biological and chronological age, highli...

How to measure consumer's inconsistency in sensory testing?

Consumer sensory testing is the basis for determining directions of product development in the food industry. However, while compliance assessment by trained and expert assessors is well developed, few information is available on testing co...

Lie Symmetry Analysis of C1m,a,b Partial Differential Equations

In this article, we discussed the Lie symmetry analysis of C1m,a,b fractional and integer order differential equations. The symmetry algebra of both differential equations is obtained and utilized to find the similarity reductions, invarian...

Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)

Abstract Background Older adults have been disproportionately impacted by COVID-19 and related preventative measures undertaken during the pandemic. Given clear evidence of the relationship between loneliness and health outcomes, it is impe...

BUGSnet: an R package to facilitate the conduct and reporting of Bayesian network Meta-analyses

Abstract Background Several reviews have noted shortcomings regarding the quality and reporting of network meta-analyses (NMAs). We suspect that this issue may be partially attributable to limitations in current NMA software which do not re...