Academic Articles & Research Papers

Editorial: Application of network-theoretic approaches in biology

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Add...

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis

Abstract Background Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stabil...

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

PRODUCTION OF L-TRYPTOPHAN BY MUTANTS OF CORYNEBACTERIUM GLUTAMICUM

L-Tryptophan, is one of the amino acids, also is one of the 9 essential amino acids of human which cannot be synthesized internally by him, microbial production is the main method for obtaining tryptophan for commercial uses. Typical microo...

Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

Abstract Background Articular injection of mesenchymal stem cells (MSCs) has been applied to treat knee osteoarthritis (kOA), but its clinical outcomes are controversial. This study investigated whether an articular inflammatory microenviro...

Prenatal diagnosis of mosaicism for double aneuploidy of 47,XXY and trisomy 7 (48,XXY,+7) at amniocentesis in a pregnancy with a favorable outcome

Objective: We present prenatal diagnosis of mosaicism for double aneuploidy of 47, XXY and trisomy 7 (48,XXY,+7) at amniocentesis in a pregnancy with a favorable outcome. Case report: A 33-year-old woman underwent amniocentesis at 17 weeks ...

Accomplishments in genome‐scale in silico modeling for industrial and medical biotechnology

Driven by advancements in high-throughput biological technologies and the growing number of sequenced genomes, the construction of in silico models at the genome scale has provided powerful tools to investigate a vast array of biological sy...

Medical biotechnology

This chapter explains the role of biotechnology in medicine and explores the process of making antibodies and hybridoma technology. It shows how vaccines are manufactured and discusses the significance of stem cell therapy and the related i...

Patricia Knapp's Landmark Project to Develop a Plan of Curriculum-Integrated Library Instruction

A Review of: Knapp, P. B. (1966). The Monteith College library experiment. New York, NY: Scarecrow Press. Objective — To create a college-level, four-year plan of library instruction in which assignments directly relate to students' ...

Benefits of Using Early Warning Scores - A Systematic Review

The Early Warning Scores (EWSs) are tools for bedside evaluation based on five physiological parameters: systolic pressure, pulse, respiratory rate, body temperature and AVPU (alert, voice, pain, unresponsive) score. EWSs have been used in ...

Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study

BackgroundAnimal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate ...

A missed opportunity: faith leaders and the HPV vaccination effort in Addis Ababa, Ethiopia

Background Cervical cancer causes morbidity and mortality among women worldwide, particularly in low- and middle-income countries (LMICs). Human Papillomavirus (HPV) vaccine is crucial for cervical cancer prevention, yet the vaccination rat...

How Does the Diversity of Divers Affect the Design of Citizen Science Projects?

Divers have widely participated in citizen science (CS) projects and are one of the main groups of marine citizen scientists. However, there is little knowledge about profiles of, and incentives for potential divers to join CS projects. To ...

Symbolic CSR and public responses among young Chinese social media users: dual mediation of skepticism and trust, moderated by algorithmic ethical perception

Drawing on signaling theory and the cognitive-affective framework, this study developed a moderated serial mediation model to explain how perceived symbolic CSR is associated with public responses in algorithm-mediated environments. It exam...

Impact of patient-centered communication on patient satisfaction scores in patients with chronic life-limiting illnesses: an experience from Kenya

BackgroundPatient satisfaction remains a key area of interest worldwide; utilizing a patient-centered communication approach, particularly with patients with chronic life-limiting illnesses may be one way to achieve this. However, there is ...

Adaptive Cloud-Based Extended Reality: Modeling and Optimization

Extended Reality (XR) — which includes Virtual Reality and Augmented Reality — promises to bring the virtual and telepresence experience to another level. Unfortunately, solutions leveraging these technologies require special ...

Cultural and communication studies: Sebuah pengantar paling komprehensif

Communication Studies: Effective Communication Leads to Effective Leadership

This chapter explores how communication studies focuses on human communication among people in groups, teams, and organizations. While persuasive communication has long been at the heart of leadership development, the discipline's contribut...

Consumers perception on green marketing towards eco-friendly fast moving consumer goods

In today’s commercial world, ecological concerns have become increasingly essential. A lot of governments care about environmental issues. Sustainable development that doesn’t harm the environment is a major concern for companies today. The...