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Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway

Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine (2024)

Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-024-05257-w

Correcting palindromes in long reads after whole-genome amplification

Sven Warris, Elio Schijlen, Henri van de Geest, Rahulsimham Vegesna et al. • BMC Genomics (2018)

Abstract Background Next-generation sequencing requires sufficient DNA to be available. If limited, whole-genome amplification is applied to generate additional amounts of DNA. Such amplification often results in many chimeric DNA fragments...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12864-018-5164-1

Cerebrospinal fluid-stem cell interactions may pave the path for cell-based therapy in neurological diseases

Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy (2018)

Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13287-018-0807-3

Water and soil pollution as determinant of water and food quality/contamination and its impact on female fertility

Justin Rashtian, Diana E. Chavkin, Zaher Merhi • Reproductive Biology and Endocrinology (2019)

Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse repr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12958-018-0448-5

The Effect of Capital Intensity, Audit Quality, Thin Capitalization, and Gender Diversity on Tax Aggressiveness

Yoga Adi Pratama, Muhammad Abdul Aris • Indonesian Interdisciplinary Journal of Sharia Economics (2024)

This study aims to analyze the effects of capital intensity, audit quality, thin capitalization, and gender diversity on tax aggressiveness in state-owned enterprises (SOEs) listed on the Indonesia Stock Exchange (IDX) from 2020 to 2023. Th...

DOAJ Open Access (DOAJ) DOI: 10.31538/iijse.v8i1.6010

Data-Driven Cooperative Control Model of Shearer-Scraper Conveyor Based on Rough Set Theory

Shuanfeng Zhao, Jiaojiao Zhao, Jiaojiao Zhao, Zhengxiong Lu et al. • Frontiers in Energy Research (2022)

The cooperative control of shearer and scraper conveyors is the prerequisite for the realization of intelligent comprehensive mining equipment and unmanned comprehensive mining workings. However, because of the harsh working face environmen...

DOAJ Open Access (DOAJ) DOI: 10.3389/fenrg.2022.811648

Hybrid Dynamic Traffic Model for Freeway Flow Analysis Using a Switched Reduced-Order Unknown-Input State Observer

Yuqi Guo, Bin Li, Matthew Daniel Christie, Zongzhi Li et al. • Sensors (2020)

This paper introduces a new methodology for reconstructing vehicle densities of freeway segments by utilizing the limited data collected by traffic-counting sensors and developing a macroscopic traffic stream model formulated as a switched ...

DOAJ Open Access (DOAJ) DOI: 10.3390/s20061609

Impacts of land-use changes and landholding fragmentation on crop water demand and drought in Wadi El-Farigh, New Delta project, Egypt

Mohamed M. Elsharkawy, Mohsen Nabil, Eslam Farg, Sayed M. Arafat • Egyptian Journal of Remote Sensing and Space Sciences (2022)

Despite Egypt’s limited water resources, more lands in the western desert of the Nile Delta are currently being reclaimed to increase the agricultural area to feed its fast-growing population and provide jobs for new generations. These recl...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejrs.2022.08.002

Natural Earth Pigments as Geological Polymineral Systems: A Structured Approach to Provenance and Degradation Assessment in Heritage Science

Sebastiano Ettore Spoto, Roberta Somma • Heritage (2026)

Natural earth pigments are polymineral materials whose present composition may differ from the source because of selection, grinding, heating, mixing, binder incorporation, and later alteration. This study develops a structured method for s...

DOAJ Open Access (DOAJ) DOI: 10.3390/heritage9080322

An Adaptive JPEG Double Compression Steganographic Scheme Based on Irregular DCT Coefficients Distribution

Ju Jia, Zhaoxia Xiang, Lina Wang, Yan Xu • IEEE Access (2019)

Steganography is to embed secret information into digital media and minimize the distortion caused by data embedding. The JPEG is a widely used image compression format, and many JPEG images transmitted on the network are double compressed....

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2019.2926226

Two-dimensional metallic tantalum ditelluride with an intrinsic basal-plane activity for oxygen reduction: A microkinetic modeling study

Yu Wang, Kun Zhou • Green Energy & Environment (2022)

Two-dimensional (2D) materials have exhibited great potential for replacing costly Pt for oxygen reduction reaction (ORR) because of their distinctive structural features and high pre-site activity. However, their performance is generally h...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.gee.2020.11.003

Evaluation of joint and muscle function of paediatric upper and lower extremities

Mohamed Afifi, Mohamed Afifi, Muhammad Uba Abdulazeez, Muhammad Uba Abdulazeez et al. • Frontiers in Bioengineering and Biotechnology (2025)

Road traffic crashes are the leading cause of injuries, disabilities, and fatalities for children and young adults. Extremity joint injuries have been identified as one of the contributing factors to chronic disabilities among children in r...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2025.1667865

On Combined Maximal Precedence–Exceedance Test with Application to HIV Clinical Trials

Sylvester Sebola, Niladri Chakraborty, Morné Rowan Sjölander • Mathematics (2026)

This paper proposes a combined maximal precedence–exceedance test (MPErs) that integrates maximal precedence and maximal exceedance statistics tests to provide sensitivity to both early and late distributional differences between two sample...

DOAJ Open Access (DOAJ) DOI: 10.3390/math14203658

Empirical study on optimal reinsurance for crop insurance in China from an insurer's perspective

Xian-hua ZHOU, Yun-bo WANG, Hua-dong ZHANG, Ke WANG • Journal of Integrative Agriculture (2015)

This study investigates the optimal reinsurance for crop insurance in China in an insurer's perspective using the data from Inner Mongolia, Jilin, and Liaoning, China. On the basis of the loss ratio distributions modeled by AnHua Crop Risk ...

DOAJ Open Access (DOAJ) DOI: 10.1016/S2095-3119(14)60998-9

Modelling the adsorption of iron and manganese by activated carbon from teak and shea charcoal for continuous low flow

Worlanyo Kwadjo Siabi, Emmanuel Degraft-Johnson Owusu-Ansah, Helen Michelle Korkor Essandoh, Nana Yaw Asiedu • Water-Energy Nexus (2021)

Nearly 6494 boreholes with iron (Fe) and manganese (Mn) concentrations above permissible limits of 0.3 mg/L and 0.4 mg/L respectively in Ghana have been abandoned because of ineffective water treatment solutions. Activated carbon prepared f...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.wen.2021.02.001

Beyond airborne spread: a dual-route Wells-Riley extension for estimating norovirus infection risk in Ghanaian pediatric wards

Jennifer Belt Antwi, Nana Kena Frempong • Mathematics in Medical and Life Sciences (2026)

Background: The classic Wells–Riley model (CWRM) is a well-established framework for estimating airborne infection risk in shared indoor environments. This study extends the framework to simultaneously incorporate fecal–oral transmission, a...

DOAJ Open Access (DOAJ) DOI: 10.1080/29937574.2026.2714847