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Academic Articles & Research Papers
Showing 20 of 4,201 academic articles
S. H. Ubohov, V. V. Trokhymchuk, G. V. Zagoriy, L. O. Fedorova • Фармацевтичний журнал
(2019)
One of the most promising ways to increase the efficiency of pharmaceutical enterprises in the field of quality assurance of medicines is the introduction of integrated quality systems (IQS).
The aim of the work is to study of the state ...
DOAJ
Open Access (DOAJ)
DOI: 10.32352/0367-3057.2.19.01
Santiago Palacios • Drugs in Context
(2020)
The menopause-related decline in estrogen levels leads to an array of genital, sexual, and urinary symptoms collectively known as genitourinary syndrome of menopause. The constellation of symptoms associated with vulvar and vaginal atrophy ...
DOAJ
Open Access (DOAJ)
DOI: 10.7573/dic.2020-3-2
Lizel Göranson, Olof Svensson, Olof Svensson, Peter Andiné et al. • Frontiers in Psychiatry
(2022)
BackgroundWhich type of information experts use to make decisions regarding legal insanity within forensic psychiatric investigations (FPI) is relatively unknown, both in general and when considering variations due to case context. It is im...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fpsyt.2022.822519
Aleš Kopal, Eva Mejzlíková, Jana Lízrová Preiningerová, David Brebera et al. • Parkinson's Disease
(2015)
Parkinson’s disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+) have s...
DOAJ
Open Access (DOAJ)
DOI: 10.1155/2015/709191
Emma R. Francis, Daniela Fonseca de Freitas, Craig Colling, Megan Pritchard et al. • BJPsych Open
(2021)
We describe the incidence of suicidality (2007–2017) in people with depression treated by secondary mental healthcare services at South London and Maudsley NHS Trust (n = 26 412). We estimated yearly incidence of ‘suicidal ideation’ and ‘hi...
DOAJ
Open Access (DOAJ)
DOI: 10.1192/bjo.2021.1054
Rutger Osterthun, Katharina Sunnerhagen, Henk J. Stam, Carlotte Kiekens • Journal of Rehabilitation Medicine
(2023)
Objective: As Physical and Rehabilitation Medicine physicians are experts in functional prognoses of disabling health conditions, the aim of this study was to gain insight into their involvement in end-of-life decisions in patients with neu...
DOAJ
Open Access (DOAJ)
DOI: 10.2340/jrm.v55.5575
Ashley eNovais, Ashley eNovais, Ana Catarina Ferreira, Ana Catarina Ferreira et al. • Frontiers in Behavioral Neuroscience
(2013)
Neudesin (also known as neuron derived neurotrophic factor, Nenf) is a scarcely studied putative non-canonical neurotrophic factor. In order to understand its function in the brain, we performed an extensive behavioral characterization (mot...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnbeh.2013.00119
Jonathan D. Cherry, Jesse Mez, John F. Crary, Yorghos Tripodis et al. • Acta Neuropathologica Communications
(2018)
Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodege...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s40478-018-0619-9
Susheel Kumar Nethi, Venugopal Gunda, Nagabhishek Sirpu Natesh, Brianna M. White et al. • iScience
(2025)
Summary: Pancreatic cancer (PC) exhibits profound metabolic adaptations that support tumor progression, survival, and therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of these processes, promoting metabolic reprog...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.isci.2025.114088
Mateusz Kudelko, Peikai Chen, Vivian Tam, Ying Zhang et al. • Matrix Biology Plus
(2021)
Mice are commonly used to study intervertebral disc (IVD) biology and related diseases such as IVD degeneration. Discs from both the lumbar and tail regions are used. However, little is known about compartmental characteristics in the diffe...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.mbplus.2021.100082
Yunhan Zhang, Ying Zhang, Jiaoyan Song, Ziwen Zhao et al. • Scientific Reports
(2026)
Abstract Piezo1 plays a key role in the immune response during sepsis. To date, our understanding of the role of Piezo1 in inflammatory diseases has mostly been limited to influencing vasomotor function and regulating inflammatory infiltrat...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-025-34794-7
Santiago Radío, Santiago Radío, Rafael Sebastián Fort, Rafael Sebastián Fort et al. • Frontiers in Genetics
(2018)
Most signals involved in post-transcriptional regulatory networks are located in the untranslated regions (UTRs) of the mRNAs. Therefore, to deepen our understanding of gene expression regulation, delimitation of these regions with high acc...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fgene.2018.00671
Marta Alonso-Hearn, Gerard Badia-Bringué, Maria Canive • Frontiers in Veterinary Science
(2022)
Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease or paratuberculosis (PTB), with important animal health and economic implications. There are no therapeutic strategies to control this disease, and vaccination with in...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fvets.2022.935133
M. Jane Morwitzer, Ying Yi Zheng, Heather Friberg, Jeffrey R. Currier • Frontiers in Immunology
(2025)
Dengue is caused by the four serotypes of dengue virus (DENV-1-4) and poses a significant global public health challenge, with an estimated 100–400 million infections annually. Severe dengue manifestations, such as Dengue Hemorrhagic Fever ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2025.1618650
Eva Klingberg, Maria K. Magnusson, Hans Strid, Anna Deminger et al. • Arthritis Research & Therapy
(2019)
Abstract Background Ankylosing spondylitis (AS) shares many characteristics with inflammatory bowel disease (IBD). Intestinal microbiota most likely plays an important role in the development of IBDs and may also be involved in the pathogen...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s13075-019-2018-4
Qingwei Wu, Zhifa Ge, Chengyu Lv, Qifeng He • Frontiers in Immunology
(2025)
Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2025.1584001
Massimiliano S. Tagliamonte, Charles A. Yowell, Maha A. Elbadry, Jacques Boncy et al. • mSphere
(2020)
ABSTRACT The malaria parasite, Plasmodium falciparum, was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries. During this period, more than 12 million Africans w...
DOAJ
Open Access (DOAJ)
DOI: 10.1128/mSphere.00937-20
Whitni K. Redman, Garrett S. Welch, Avery C. Williams, Addyson J. Damron et al. • Biofilm
(2021)
Novel anti-biofilm and dispersal agents are currently being investigated in an attempt to combat biofilm-associated wound infections. Glycoside hydrolases (GHs) are enzymes that hydrolyze the glycosidic bonds between sugars, such as those f...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.bioflm.2021.100061
Oliver H. Bell, David A. Copland, Amy Ward, Lindsay B. Nicholson et al. • Frontiers in Immunology
(2020)
Background: Whether retinal microglia can maintain or restore immune homeostasis during and after inflammation is unclear. We performed single-eye mRNA-sequencing on microglia at different timepoints following a single inflammatory stimulus...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fimmu.2019.03033
Yvonne Tan, Danielle Pinder, Imaan Bayoumi, Rifaa Carter et al. • International Journal for Equity in Health
(2024)
Abstract Background Adverse childhood experiences (ACEs), in combination with adverse community environments, can result in traumatic stress reactions, increasing a person’s risk for chronic physical and mental health conditions. Family res...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12939-024-02142-2