Academic Articles & Research Papers

ZX-Diagram T-Count Reduction Based on Proximal Policy Optimization

In fault-tolerant quantum computing systems, the T gates consume more fault-tolerant resources. In this paper, we propose an automated optimization method based on the Proximal Policy Optimization (PPO) algorithm. We first translate quantum...

Survey of Quantum Computing Simulation and Optimization Methods

Through superposition and entanglement, a quantum computing displays significant advantages over classical computers in dealing with problems that require large-scale parallel processing capabilities.At present, a physical quantum computer ...

Lightweight Anonymous Group Authentication and Quantum-Cloud Key Distribution Based on PUF for Classical Network Environments

With the rapid development of quantum computing, in response to its disruptive threats to traditional cryptosystems and the urgent demand for lightweight and highly scalable secure group communication among resource-constrained devices in l...

Quantum Computing Explained

A self-contained treatment of the fundamentals of quantum computing This clear, practical book takes quantum computing out of the realm of theoretical physics and teaches the fundamentals of the field to students and professionals who ha...

Quantum computing

The subject of quantum computing brings together ideas from classical information theory, computer science, and quantum physics. This review aims to summarize not just quantum computing, but the whole subject of quantum information theory. ...

AMPA-Type Glutamate Receptors Associated With Vascular Smooth Muscle Cell Subpopulations in Atherosclerosis and Vascular Injury

Objectives and Aims: Vascular smooth muscle cells (VSMCs) are key constituents of both normal arteries and atherosclerotic plaques. They have an ability to adapt to changes in the local environment by undergoing phenotypic modulation. An im...

The human lung microbiome progressively diminishes in the distal alveolar regions

Abstract Extensive investigations with sequencing methods demonstrate a large and diverse microbiome even in profound areas of the lung. However, there is still substantial lack of cultivation-based evidence and of the viability of the resi...

Unrevealing the dual role of paired box and sex determining region Y related high mobility group box in glioblastoma

Abstract This narrative review summarises glioblastoma (GBM), a very frequent invasive kind of brain tumour in the elderly that is extremely aggressive, resistant to treatment, and has a bad prognosis because of its substantial genetic and ...

Molecular Biology and Pathogenicity of Mycoplasmas

Plant Molecular Biology Manual

Ontologies for molecular biology.

Molecular biology has a communication problem. There are many databases using their own labels and categories for storing data objects and some using identical labels and categories but with a different meaning. A prominent example is the c...

Low Pathogenic Avian Influenza H9N2 Viruses in Morocco: Antigenic and Molecular Evolution from 2021 to 2023

Avian influenza viruses pose significant threats to both the poultry industry and public health worldwide. Among them, the H9N2 subtype has gained substantial attention due to its high prevalence, especially in Asia, the Middle East, and Af...

USP1-trapping lesions as a source of DNA replication stress and genomic instability

Here the authors provide mechanistic insights into how auto-cleavage of the USP1 deubiquitinase regulates DNA replication and genome stability. Implications for the targeting of USP1 activity via protein-DNA trapping in cancer therapy are d...

Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome

Abstract Background Human exposure to high doses of radiation resulting in acute radiation syndrome and death can rapidly escalate to a mass casualty catastrophe in the event of nuclear accidents or terrorism. The primary reason is that the...

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss

Selenoprotein N (SELENON) is an endoplasmic reticulum (ER) protein whose loss of function leads to human SELENON-related myopathies. SelenoN knockout (KO) mouse limb muscles, however, are protected from the disease, and display no major alt...

Challenges in community-based recruitment of Alzheimer's disease cases: Experience of the monitoring drug efficacy through multi-omics research initiative in Alzheimer's disease (MEMORI-AD) study

Background The Monitoring drug Efficacy through Multi-Omics Research Initiative in Alzheimer's Disease (MEMORI-AD) study aims to characterize drug response to donepezil and memantine in a Filipino cohort with late-onset Alzheimer's disease ...

High helminthic co-infection in tuberculosis patients with undernutritional status in northeastern Ethiopia

Abstract Background Tuberculosis and parasitosis are the widely distributed diseases in Ethiopia with the leading cause of mortality and morbidity, respectively. There has been no information on the status of co-infections of tuberculosis a...

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

The molecular biology of the mycobacteria is poised at the threshold of making major contributions to the understanding of the biochemistry and pathogenic mechanisms involved in mycobacterial infections.The application of molecular biology ...

Graphs in molecular biology

Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and their areas of application in molecular biology. We d...

That Was the Molecular Biology That Was

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