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The human lung microbiome progressively diminishes in the distal alveolar regions

Pauline Potratz, Antje Häder, Laura Kursawe, Judith Kikhney et al. • npj Biofilms and Microbiomes (2026)

Abstract Extensive investigations with sequencing methods demonstrate a large and diverse microbiome even in profound areas of the lung. However, there is still substantial lack of cultivation-based evidence and of the viability of the resi...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41522-026-01047-y

Towards robust distributed systems (abstract)

Eric A. Brewer • ACM Symposium on Principles of Distributed Computing (PODC) (2000)

Current distributed systems, even the ones that work, tend to be very fragile: they are hard to keep up, hard to manage, hard to grow, hard to evolve, and hard to program. In this talk, I look at several issues in an attempt to clean up the...

OPENALEX DOI: https://doi.org/10.1145/343477.343502

Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies

M. Camila Melo-Narvaez, Fee Gölitz, Eshita Jain, Janine Gote-Schniering et al. • Respiratory Research (2025)

Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research. However, tissue availability, generation, and cultivation time r...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12931-025-03132-w

Biological Potential of <i>Tsuga canadensis</i>: A Study on Seed, Cone Essential Oils, and Seed Lipophilic Extract

Anna Wajs-Bonikowska, Ewa Maciejczyk, Łukasz Szoka, Paweł Kwiatkowski et al. • Applied Sciences (2025)

This study investigates the essential oil (EO) isolated from the seeds and cones of Canadian hemlock (Tsuga canadensis), highlighting notable differences in their chemical composition and biological activities. The seed EO was uniquely domi...

DOAJ Open Access (DOAJ) DOI: 10.3390/app15041713

Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8+ T cells towards the center of human lung tumors

Demi Brownlie, Andreas von Kries, Giampiero Valenzano, Nicole Wild et al. • OncoImmunology (2023)

Lung cancer is a leading cause of cancer-related death worldwide. Despite recent advances in tissue immunology, little is known about the spatial distribution of tissue-resident lymphocyte subsets in lung tumors. Using high-parameter flow c...

DOAJ Open Access (DOAJ) DOI: 10.1080/2162402X.2023.2233402

Saccharomyces boulardii RC009 as an alternative to prophylactic antibiotics: effects on broiler chickens, performance, and gut microbiome

Alejandra Magnoli, María Luna, Laureano Giordano, Maite Isgro et al. • Iraqi Journal of Veterinary Sciences (2026)

This study evaluates the effects of supplementing broiler chicken feed with the probiotic Saccharomyces cerevisiae var. boulardii RC009 as a sustainable alternative to prophylactic antibiotics. The focus was on productive performance, gut m...

DOAJ Open Access (DOAJ) DOI: 10.33899/ijvs.2025.166858.4600

Free Amino Acids in Human Milk: A Potential Role for Glutamine and Glutamate in the Protection Against Neonatal Allergies and Infections

Joris H. J. van Sadelhoff, Selma P. Wiertsema, Johan Garssen, Johan Garssen et al. • Frontiers in Immunology (2020)

Breastfeeding is indicated to support neonatal immune development and to protect against neonatal infections and allergies. Human milk composition is widely studied in relation to these unique abilities, which has led to the identification ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2020.01007

Improving Muscle Function Through a Multimodal Behavioural Intervention for Knee Osteoarthritis and Obesity: The POMELO Trial

Kristine Godziuk, Mary Forhan, Flavio T. Vieira, Joao F. Mota et al. • Journal of Cachexia, Sarcopenia and Muscle (2025)

ABSTRACT Background Treatments aimed at improving physical function and body composition, including reducing fat mass (FM) and increasing muscle mass, may benefit individuals with advanced knee osteoarthritis (OA) and obesity. We investigat...

DOAJ Open Access (DOAJ) DOI: 10.1002/jcsm.70025

The use of plant waste to ensure the functioning of agricultural energy complexes

M. F. Nabiullina, G. R. Mingaleeva, O. V. Afanaseva, S. S. Timofeeva • Известия высших учебных заведений: Проблемы энергетики (2024)

RELEVANCE. Agricultural enterprises generate vegetable waste, which is difficult to utilize. Such waste can be used for combustion in boilers, providing thermal and electric energy to an agricultural energy complex. A hybrid mini-thermal po...

DOAJ Open Access (DOAJ) DOI: 10.30724/1998-9903-2024-26-3-120-131

Electrospinning: A Powerful Tool to Improve the Corrosion Resistance of Metallic Surfaces Using Nanofibrous Coatings

Pedro J. Rivero, Deyo Maeztu Redin, Rafael J. Rodríguez • Metals (2020)

The use of surface engineering techniques to tune-up the composition of nanostructured thin-films for developing functional coatings with advanced properties is a hot topic within the scientific community. The control of the coating structu...

DOAJ Open Access (DOAJ) DOI: 10.3390/met10030350

Phase formations and microstructures of Ti20Zr15Hf15Ni35Cu15 high-entropy shape memory alloy under different aging conditions

Yen-Ting Chang, Ming-Hao Lee, Ming-Wen Chu, Chih-Hsuan Chen • Materials Today Advances (2022)

The microstructures and phase formations of Ti20Zr15Hf15Ni35Cu15 high entropy shape memory alloy (HESMA) under different aging conditions were investigated in this study. At aging temperatures below 500 °C, a large amount of the H-phase for...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.mtadv.2022.100223

Active galactic nucleus activity in nearby disk galaxies: The roles of bar strength and spiral arm morphology

Martirosyan Zh. R., Hakobyan A. A., Adibekyan V., Barkhudaryan L. V. et al. • Astronomy & Astrophysics (2026)

Context. The transport of gas toward galactic centers and its connection to active galactic nucleus (AGN) activity remain key open questions in galaxy evolution. In particular, the relative roles of stellar bars and spiral arms and their po...

DOAJ Open Access (DOAJ) DOI: 10.1051/0004-6361/202661413

Potential of Radioactive Isotopes Production in DEMO for Commercial Use

Pavel Pereslavtsev, Christian Bachmann, Joelle Elbez-Uzan, Jin Hun Park • Applied Sciences (2024)

There is widespread use of nuclear radiation for medical imagery and treatments. Worldwide, almost 40 million treatments are performed per year. There are also applications of radiation sources in other commercial fields, e.g., for weld ins...

DOAJ Open Access (DOAJ) DOI: 10.3390/app14010442

A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin

Eva Klingberg, Maria K. Magnusson, Hans Strid, Anna Deminger et al. • Arthritis Research & Therapy (2019)

Abstract Background Ankylosing spondylitis (AS) shares many characteristics with inflammatory bowel disease (IBD). Intestinal microbiota most likely plays an important role in the development of IBDs and may also be involved in the pathogen...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-019-2018-4

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Qingwei Wu, Zhifa Ge, Chengyu Lv, Qifeng He • Frontiers in Immunology (2025)

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2025.1584001

Improving the Transferability of Suspended Solid Estimation in Wetland and Deltaic Waters with an Empirical Hyperspectral Approach

Daniel Jensen, Marc Simard, Kyle Cavanaugh, Yongwei Sheng et al. • Remote Sensing (2019)

The deposition of suspended sediment is an important process that helps wetlands accrete surface material and maintain elevation in the face of sea level rise. Optical remote sensing is often employed to map total suspended solids (TSS), th...

DOAJ Open Access (DOAJ) DOI: 10.3390/rs11131629