Reset
Showing 20 of 881 academic articles

GPR55 activation improves anxiety- and depression-like behaviors of mice during methamphetamine withdrawal

Jinlong Zhang, Jie Yan, Shuyue Li, Qianqian Chen et al. • Heliyon (2024)

Methamphetamine is a potent and highly addictive neurotoxic psychostimulant that triggers a spectrum of adverse emotional responses during withdrawal. G-protein coupled receptor 55 (GPR55), a novel endocannabinoid receptor, is closely assoc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e30462

Emodin, an Emerging Mycotoxin, Induces Endoplasmic Reticulum Stress-Related Hepatotoxicity through IRE1α–XBP1 Axis in HepG2 Cells

Su Been Park, Gun Hee Cho, Young Eun Park, Hyang Sook Chun • Toxins (2023)

Emodin, an emerging mycotoxin, is known to be hepatotoxic, but its mechanism remains unclear. We hypothesized that emodin could induce endoplasmic reticulum (ER) stress through the inositol-requiring enzyme 1 alpha (IRE1α)–X-box-binding pro...

DOAJ Open Access (DOAJ) DOI: 10.3390/toxins15070455

DNA polymorphisms in inflammatory and endocrine signals linked to frailty are also associated with obesity: data from the FRASNET cohort

Sarah Damanti, Sarah Damanti, Lorena Citterio, Laura Zagato et al. • Frontiers in Endocrinology (2024)

BackgroundObesity and frailty are prevalent geriatric conditions that share some pathophysiological mechanisms and are associated with adverse clinical outcomes. The relationship between frailty, obesity, and polymorphism remains inadequate...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2024.1412160

Evaluation of clinical quality improvement interventions: feasibility of an integrated approach

Sandeep Reddy, Kevin Mc Namara, Mary Malakellis, Tim Denton et al. • Pilot and Feasibility Studies (2019)

Abstract Background Cardiovascular diseases (CVD) are the largest cause of death and disability in Australia. Australian national guidelines for the primary prevention of CVD recommend that all adults without CVD and aged 45 years or more a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40814-018-0386-1

Understanding the Influence of Personalized Recommendation on Purchase Intentions from a Self-Determination Perspective: Contingent upon Product Categories

Li Zhao, Bing Fu, Sha Bai • Journal of Theoretical and Applied Electronic Commerce Research (2025)

While consumers experience shopping convenience through personalized recommendations, they are increasingly concerned about their consumption behavior being manipulated, leading to psychological resistance towards personalized recommendatio...

DOAJ Open Access (DOAJ) DOI: 10.3390/jtaer20010032

Botnet detection using graph-based feature clustering

Sudipta Chowdhury, Mojtaba Khanzadeh, Ravi Akula, Fangyan Zhang et al. • Journal of Big Data (2017)

Abstract Detecting botnets in a network is crucial because bots impact numerous areas such as cyber security, finance, health care, law enforcement, and more. Botnets are becoming more sophisticated and dangerous day-by-day, and most of the...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40537-017-0074-7

IMPROVEMENT OF CREATIVITY IN MATHEMATICS STUDENTS THROUGH THE AUDITORY INTELLECTUAL REPETITION (AIR) LEARNING MODEL

Nur Asrawati, Sitti Fatimah Sangkala Sirate • MaPan: Jurnal Matematika dan Pembelajaran (2022)

This study aims to determine the increase in students' mathematical creativity through the auditory, intellectual, repetition (AIR) learning model in class XI students of SMK Techno Terapan Makassar. Creativity referred to in this study pay...

DOAJ Open Access (DOAJ) DOI: 10.24252/mapan.2022v10n2a5

Agent-based multi-tier SLA negotiation for intercloud

Lin Li, Li Liu, Shalin Huang, Shibiao Lv et al. • Journal of Cloud Computing: Advances, Systems and Applications (2022)

Abstract The evolving intercloud enables idle resources to be traded among cloud providers to facilitate utilization optimization and to improve the cost-effectiveness of the service for cloud consumers. However, several challenges are rais...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13677-022-00286-6

On the Domain of 4-Dimensional Catalan Matrix in the Space of Absolutely Summable Double Sequences

Sezer Erdem, Serkan Demiriz • Universal Journal of Mathematics and Applications (2025)

The primary objective of this study is to construct a novel double sequence space by utilizing the domain of a 4-dimensional (4D) matrix in the space $\mathcal{L}_u$ of the absolutely summable double sequences defined via the well-known Ca...

DOAJ Open Access (DOAJ) DOI: 10.32323/ujma.1734157

Analysis of Long-Term Impact of Maintenance Policy on Maintenance Capacity Using a Time-Driven Activity-Based Life-Cycle Costing

Orlando Durán, Paulo Afonso, Vinicius Minatogawa • Mathematics (2020)

In capital-intensive industries, physical assets and maintenance activities play a relevant and strategic role in terms of providing operational continuity and business sustainability. As a result, maintenance support structures are highly ...

DOAJ Open Access (DOAJ) DOI: 10.3390/math8122208

Multi-step prediction in linearized latent state spaces for representation learning

Andrii Tytarenko • Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï (2022)

In this paper, we derive a novel method as a generalization over LCEs such as E2C. The method develops the idea of learning a locally linear state space by adding a multi-step prediction, thus allowing for more explicit control over the cur...

DOAJ Open Access (DOAJ) DOI: 10.20535/SRIT.2308-8893.2022.3.09

The Philosophy of Mathematical Practice

Paolo Mancosu • Oxford University Press eBooks (2008)

Contemporary philosophy of mathematics offers us an embarrassment of riches. Among the major areas of work one could list developments of the classical foundational programs, analytic approaches to epistemology and ontology of mathematics, ...

OPENALEX DOI: https://doi.org/10.1093/acprof:oso/9780199296453.001.0001

How Does Anxiety Affect the Relationship between the Customer and the Omnichannel Systems?

Bui Thanh Khoa, Tran Trong Huynh • Journal of Theoretical and Applied Electronic Commerce Research (2023)

Omnichannel is not just a marketing, e-commerce, or customer support buzzword. This future customer engagement platform helps businesses communicate with customers through centralized channels on a smart interface. It is difficult to achiev...

DOAJ Open Access (DOAJ) DOI: 10.3390/jtaer18010007

Mathematical Models in Biology

Leah Edelstein‐Keshet • Society for Industrial and Applied Mathematics eBooks (2005)

Life scientists are not always fully aware of the powerful role that mathematical models have in both answering biological research questions and in making predictions. Scientists have a clear view of the problem; they know the questions; t...

OPENALEX DOI: https://doi.org/10.1137/1.9780898719147

A Novel Energy-Efficient Reception Method Based on Random Network Coding in Cooperative Wireless Sensor Networks

Yulun Cheng, Longxiang Yang • International Journal of Distributed Sensor Networks (2015)

This paper presents an opportunistic reception (OR) algorithm for energy-efficient transmission in cooperative wireless sensor networks (WSNs), where the characteristics of random linear network coding and the energy consumption property of...

DOAJ Open Access (DOAJ) DOI: 10.1155/2015/238386