Academic Articles & Research Papers

A primer on deep learning in genomics

Using Network-Based Machine Learning to Predict Transcription Factors Involved in Drought Resistance

Gene regulatory networks underpin stress response pathways in plants. However, parsing these networks to prioritize key genes underlying a particular trait is challenging. Here, we have built the Gene Regulation and Association Network (GRA...

Decoding the genetic complexity in a pediatric case of B-ALL through long-read genomic sequencing and RNA sequencing.

Machine Learning in Healthcare

Recent advancements in Artificial Intelligence (AI) and Machine Learning (ML) technology have brought on substantial strides in predicting and identifying health emergencies, disease populations, and disease state and immune response, among...

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Abstract Background Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary and 3D stru...

Modern breeding of root, tuber, and bulb crops to enhance food and nutritional security.

Machine learning for precision medicine

Precision medicine is an emerging approach to clinical research and patient care that focuses on understanding and treating disease by integrating multi-modal or multi-omics data from an individual to make patient-tailored decisions. With t...

Machine learning applications in genetics and genomics

Tackling visual impairment: emerging avenues in ophthalmology

Visual impairment, stemming from genetic, degenerative, and traumatic causes, affects millions globally. Recent advancements in ophthalmology present novel strategies for managing and potentially reversing these conditions. Here, we explore...

A multi-organization epigenetic age prediction based on a channel attention perceptron networks

DNA methylation indicates the individual’s aging, so-called Epigenetic clocks, which will improve the research and diagnosis of aging diseases by investigating the correlation between methylation loci and human aging. Although this discover...

Precision Periodontics: Reimagining Periodontal Care through Precision Diagnostics and Targeted Therapies

Periodontitis is a chronic inflammatory disease that affects the tissues supporting teeth and represents a significant global health issue. Traditional diagnostic and treatment methods often use a broad approach and fall short due to the co...

Artificial intelligence in plant breeding

Harnessing cutting-edge technologies to enhance crop productivity is a pivotal goal in modern plant breeding. Artificial intelligence (AI) is renowned for its prowess in big data analysis and pattern recognition, and is revolutionizing nume...

Artificial Intelligence: A Modern Approach

Humankind has given itself the scientific name homo sapiens--man the wise--because our mental capacities are so important to our everyday lives and our sense of self. The field of artificial intelligence, or AI, attempts to understand intel...