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The AST/ALT ratio as a mediator of heavy metal exposure and diabetic kidney disease (DKD) risk: A NHANES study

Yu Li, Juan Chai, Jinjuan Chen, Jiayin Du et al. • Scientific Reports (2025)

Abstract The potential impact of heavy metal exposure on the progression of diabetic kidney disease (DKD) remains a subject of scientific inquiry. While some studies have hinted at a correlation, definitive evidence is still lacking. It is ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-23843-w

The Role of Cone-Beam Computed Tomography CT Extremity Arthrography in the Preoperative Assessment of Osteoarthritis

Marion Hamard, Marta Sans Merce, Karel Gorican, Pierre-Alexandre Poletti et al. • Tomography (2023)

Osteoarthritis (OA) is a prevalent disease and the leading cause of pain, disability, and quality of life deterioration. Our study sought to evaluate the image quality and dose of cone-beam computed tomography arthrography (CBCT-A) and comp...

DOAJ Open Access (DOAJ) DOI: 10.3390/tomography9060167

Evaluation of Indicators for the Realization of the Development of Public-Oriented Urban Transportation (Study Case: District 11 of Tehran)

Sayyed Jalal Aldin Hosseini, Azita Rajabi, Afshin Safahan, Aliasghar Rezvani • برنامه‌ریزی توسعه شهری و منطقه‌ای (2024)

Transit-Oriented Development (TOD) represents a significant facet of sustainable urban planning aimed at addressing urban traffic challenges through the strategic expansion of public transportation systems. District 11 within the municipali...

DOAJ Open Access (DOAJ) DOI: 10.22054/urdp.2023.55092.1248

Physicochemical- and biocompatibility of oxygen and nitrogen plasma treatment using a PLA scaffold

Ali Davoodi, Homayoun H. Zadeh, Morteza Daliri Joupari, Mohammad Ali Sahebalzamani et al. • AIP Advances (2020)

Plasma surface treatment has a wide range of applications in biomedicine. In the present study, flat polylactic acid (PLA) films were treated with oxygen and nitrogen, low-pressure, non-thermal plasma. The water contact angle of the PLA fil...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0022306

Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane

Abbirami Balachandran, Sy Bing Choi, Morak-Młodawska Beata, Jeleń Małgorzata et al. • Molecules (2023)

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral vascular disea...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28031043

The Holo-Transcriptome of the Zoantharian Protopalythoa variabilis (Cnidaria: Anthozoa): A Plentiful Source of Enzymes for Potential Application in Green Chemistry, Industrial and Pharmaceutical Biotechnology

Jean-Étienne R. L. Morlighem, Chen Huang, Qiwen Liao, Paula Braga Gomes et al. • Marine Drugs (2018)

Marine invertebrates, such as sponges, tunicates and cnidarians (zoantharians and scleractinian corals), form functional assemblages, known as holobionts, with numerous microbes. This type of species-specific symbiotic association can be a ...

DOAJ Open Access (DOAJ) DOI: 10.3390/md16060207

Interactions of cephalexin with bovine serum albumin: displacement reaction and molecular docking

Hamed Hamishehkar, Soheila Hosseini, Abdolhossein Naseri, Azam Safarnejad et al. • BioImpacts (2016)

Introduction: The drug-plasma protein interaction is a fundamental issue in guessing and checking the serious drug side effects related with other drugs. The purpose of this research was to study the interaction of cephalexin with bovine se...

DOAJ Open Access (DOAJ) DOI: 10.15171/bi.2016.19

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan et al. • Diagnostics (2018)

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been impl...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics8040079

Structure and transport mechanism of P5B-ATPases

Ping Li, Kaituo Wang, Nina Salustros, Christina Grønberg et al. • Nature Communications (2021)

In human cells, P5B‐ATPases execute export of spermine from lysosomes to the cytosol, but the mechanisms of spermine recognition, uptake and transport remain elusive. Here the authors present cryo‐EM structures of a yeast homolog of human A...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-24148-y

Complex Abdominal Wall Hernias: Structured Use of Adjuvant Therapies

Joana Marques‐Antunes, Egon Rodrigues, Marta Guimarães, Marta Guimarães et al. • Journal of Abdominal Wall Surgery (2025)

PurposeRepairing complex abdominal wall hernias is challenging, often requiring component separation techniques (CST) for tension-free closure. Adjuvant therapies, such as botulinum toxin type A (BTA), preoperative progressive pneumoperiton...

DOAJ Open Access (DOAJ) DOI: 10.3389/jaws.2025.14515

Resting-state EEG measures cognitive impairment in Parkinson’s disease

Md Fahim Anjum, Arturo I. Espinoza, Rachel C. Cole, Arun Singh et al. • npj Parkinson's Disease (2024)

Abstract Cognitive dysfunction is common in Parkinson’s disease (PD). We developed and evaluated an EEG-based biomarker to index cognitive functions in PD from a few minutes of resting-state EEG. We hypothesized that synchronous changes in ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41531-023-00602-0

Flavanol-Rich Cocoa Supplementation Inhibits Mitochondrial Biogenesis Triggered by Exercise

Jose Angel García-Merino, Beatriz de Lucas, Karen Herrera-Rocha, Diego Moreno-Pérez et al. • Antioxidants (2022)

The potential role of cocoa supplementation in an exercise context remains unclear. We describe the effects of flavanol-rich cocoa supplementation during training on exercise performance and mitochondrial biogenesis. Forty-two male enduranc...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11081522

Injectable hyaluronic acid-collagen derived hydrogel based on component biomimetic as vitreous substitute

Shuo Wang, Jinhua Chi, Yanting Wang, Ruibao Ju et al. • Materials & Design (2026)

Vitrectomy is a common clinical treatment for fundus disease. Due to the non-renewable nature of the vitreous, artificial vitreous are usually required to replace natural vitreous to perform functions post operation. Silicone oil and gas, a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.matdes.2026.115780

ABCD: advanced blockchain DSR algorithm for MANET to mitigate the different security threats

Sayan Majumder, Debika Bhattacharyya, Swati Chowdhuri • EURASIP Journal on Wireless Communications and Networking (2025)

Abstract Mobile ad hoc networks (MANETs) facilitate data communication across multiple nodes and hop stations, characterized by their dynamic topology. This inherent flexibility, however, makes MANETs vulnerable to various security threats,...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13638-025-02430-7

Lifestyle interventions to maternal weight loss after birth: a systematic review

Pernille Kjaergaard Christiansen, Mette Maria Skjøth, Mette Juel Rothmann, Christina Anne Vinter et al. • Systematic Reviews (2019)

Abstract Background Over the past decades, there has been an increase in overweight and obesity in women of childbearing age, as well as the general population. Overweight and obesity are related to a later, increased risk of type 2 diabete...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13643-019-1186-2

Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors

Kuniyasu Niizuma, Yoshikazu Ogawa, Takayuki Kogure, Teiji Tominaga • BMC Infectious Diseases (2020)

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem worldwide. More than 2 billion people have been exposed to HBV, and about 257 million individuals are chronic carriers of HBV. HBV reactivation has been ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12879-020-04971-2

A Cidade Disfuncional:

Luis Laércio Fernandes Melo, Roselane Gomes Bezerra • Conhecer (2015)

Este artigo tem o objetivo de analisar como o urbanismo contemporâneo prestigia a mobilidade e o fluxo em detrimento dos lugares destinados à habitação e relacionamentos, gerando entropia e disfuncionalidade no cotidiano dos cidadãos. A aus...

DOAJ Open Access (DOAJ)

Three Dimensions for SCO to Improve Legislation

Ван Хэюн, Д.В. Татаринов • Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì (2024)

The 21st century is the “era of international organizations”. the SCO is facing a realistic dilemma of “insufficient rule orientation”, “imperfect international law system” and “uneven level of rule of law among its members”. International ...

DOAJ Open Access (DOAJ) DOI: 10.26577/IRILJ.2024.v105.i1.011