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Single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology

Thomas Hu, Mayar Allam, Shuangyi Cai, Walter Henderson et al. • Nature Communications (2023)

Abstract Metabolic reprogramming in cancer and immune cells occurs to support their increasing energy needs in biological tissues. Here we propose Single Cell Spatially resolved Metabolic (scSpaMet) framework for joint protein-metabolite pr...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-43917-5

Physics-informed generative neural network: an application to troposphere temperature prediction

Zhihao Chen, Jie Gao, Weikai Wang, Zheng Yan • Environmental Research Letters (2021)

The troposphere is one of the atmospheric layers where most weather phenomena occur. Temperature variations in the troposphere, especially at 500 hPa, a typical level of the middle troposphere, are significant indicators of future weather c...

DOAJ Open Access (DOAJ) DOI: 10.1088/1748-9326/abfde9

Intelligent diagnosis with Chinese electronic medical records based on convolutional neural networks

Xiaozheng Li, Huazhen Wang, Huixin He, Jixiang Du et al. • BMC Bioinformatics (2019)

Abstract Background Benefiting from big data, powerful computation and new algorithmic techniques, we have been witnessing the renaissance of deep learning, particularly the combination of natural language processing (NLP) and deep neural n...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12859-019-2617-8

Medical image segmentation using deep learning: A survey

Risheng Wang, Tao Lei, Ruixia Cui, Bingtao Zhang et al. • IET Image Processing (2022)

Abstract Deep learning has been widely used for medical image segmentation and a large number of papers has been presented recording the success of deep learning in the field. A comprehensive thematic survey on medical image segmentation us...

OPENALEX cc-by DOI: https://doi.org/10.1049/ipr2.12419

Deep Learning for Massive MIMO CSI Feedback

Chao-Kai Wen, Wan-Ting Shih, Shi Jin • IEEE Wireless Communications Letters (2018)

In frequency division duplex mode, the downlink channel state information (CSI) should be sent to the base station through feedback links so that the potential gains of a massive multiple-input multiple-output can be exhibited. However, suc...

OPENALEX Open Access DOI: https://doi.org/10.1109/lwc.2018.2818160

Deep Learning in Medical Imaging: General Overview

June‐Goo Lee, Sanghoon Jun, Young-Won Cho, Hyunna Lee et al. • Korean Journal of Radiology (2017)

The artificial neural network (ANN)-a machine learning technique inspired by the human neuronal synapse system-was introduced in the 1950s. However, the ANN was previously limited in its ability to solve actual problems, due to the vanishin...

OPENALEX cc-by-nc DOI: https://doi.org/10.3348/kjr.2017.18.4.570 PMC: 5447633

Understanding tourist engagement with traditional dwellings through multimodal deep learning: a case study of the Gao Family Compound, Xi’an

Liyue Wu, Qinchuan Zhan, Yanjun Li • Humanities & Social Sciences Communications (2026)

Abstract This study applies a multimodal deep learning approach to examine tourist engagement with traditional architectural heritage. The Gao Family Compound in Xi’an serves as a representative case. Social-media texts and images from Weib...

DOAJ Open Access (DOAJ) DOI: 10.1057/s41599-026-07879-5

High-fidelity single-frame computational super-resolution using signal-preserving denoising-enabled deconvolution

Fudong Xue, Lin Yuan, Wenting He, Zuo’ang Xiang et al. • Nature Communications (2026)

Abstract Computational super-resolution (SR) methods enable nanoscale imaging from single-frame wide-field or spinning-disk confocal images without hardware modifications, yet face limitations: statistical restoration suffers from noise and...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-026-70791-8

Rethinking Gated Recurrent Units for Rotating Machinery Prognostics: A Physics-Consistency Benchmark on the Mismatch Between Gating Mechanisms and Degradation Dynamics

Zhonghua Feng, Minglun Ren • Applied Sciences (2026)

Rotating machinery prognostics is essential for ensuring the reliability and operational safety of industrial systems. Although gated recurrent units (GRUs) have achieved competitive performance in remaining useful life (RUL) prediction, wh...

DOAJ Open Access (DOAJ) DOI: 10.3390/app16178379

VulDeePecker: A Deep Learning-Based System for Vulnerability Detection

Zhen Li, Deqing Zou, Shouhuai Xu, Xinyu Ou et al. • Network and Distributed System Security Symposium (2018)

The automatic detection of software vulnerabilities is an important research problem.However, existing solutions to this problem rely on human experts to define features and often miss many vulnerabilities (i.e., incurring high false negati...

OPENALEX Open Access DOI: https://doi.org/10.14722/ndss.2018.23158

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs

Fenglei Li, Qiaoyu Hu, Xianglei Zhang, Renhong Sun et al. • Nature Communications (2022)

The rational design of PROTACs is difficult due to their obscure structure-activity relationship. Here the authors present a deep neural network model - DeepPROTACs - for predicting the degradation capacity of a proposed PROTAC molecule....

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-022-34807-3

Vison transformer adapter-based hyperbolic embeddings for multi-lesion segmentation in diabetic retinopathy

Zijian Wang, Haimei Lu, Haixin Yan, Hongxing Kan et al. • Scientific Reports (2023)

Abstract Diabetic Retinopathy (DR) is a major cause of blindness worldwide. Early detection and treatment are crucial to prevent vision loss, making accurate and timely diagnosis critical. Deep learning technology has shown promise in the a...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-38320-5