Academic Articles & Research Papers

Healthcare Management

Big Data in Healthcare Management: A Review of Literature

A systematic literature review of papers on big data in healthcare published between 2010 and 2015 was conducted. This paper reviews the definition, process, and use of big data in healthcare management. Unstructured data are growing very f...

IT applications in healthcare management: a survey

A Blockchain-Based Smart Contract System for Healthcare Management

Blockchain is evolving to be a secure and reliable platform for secure data sharing in application areas such as the financial sector, supply chain management, food industry, energy sector, internet of things and healthcare. In this paper, ...

A design thinking framework for healthcare management and innovation

Healthcare Management

Designing and Evaluation of Reliability and Validity of Visual Cue-Induced Craving Assessment Task for Methamphetamine Smokers

A B S T R A C TIntroduction: Craving to methamphetamine is a significant health concern and exposure to methamphetamine cues in laboratory can induce craving. In this study, a task designing procedure for evaluating methamphetamine cue-indu...

Alterations in white matter fiber density associated with structural MRI and metabolic PET lesions following multimodal therapy in glioma patients

BackgroundIn glioma patients, multimodality therapy and recurrent tumor can lead to structural brain tissue damage characterized by pathologic findings in MR and PET imaging. However, little is known about the impact of different types of d...

Hamartin: An Endogenous Neuroprotective Molecule Induced by Hypoxic Preconditioning

Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...

Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects

Coffee brews have High Molecular Weight (HMW) compounds with described immunostimulatory activity, namely polysaccharides and melanoidins. Melanoidins are formed during roasting and are modified during brews technological processing. In add...

The role of attachment insecurity in the emergence of anxiety symptoms in children and adolescents with migraine: an empirical study

Abstract Background It is widely recognised that there are associations between headache, psychiatric comorbidity and attachment insecurity in both adults and children. The aims of this study were: 1) to compare perceived attachment securit...

Frontiers in Human Neuroscience

Frontiers in Human Neuroscience is a first-tier electronic journal devoted to understanding the brain mechanisms supporting cognitive and social behavior in humans, and how these mechanisms might be altered in disease states. The last 25 ye...

Early childhood household instability, adolescent structural neural network architecture, and young adulthood depression: A 21-year longitudinal study

Unstable and unpredictable environments are linked to risk for psychopathology, but the underlying neural mechanisms that explain how instability relate to subsequent mental health concerns remain unclear. In particular, few studies have fo...

Increased Postural Demand Is Associated With Greater Cognitive Workload in Healthy Young Adults: A Pupillometry Study

Introduction: Balance tasks require cognitive resources to ensure postural stability. Pupillometry has been used to quantify cognitive workload of various cognitive tasks, but has not been studied in postural control. The current investigat...

Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are...

Toward an integrated approach for mental health and psychosocial support and peacebuilding in North-East Nigeria: programme description and preliminary outcomes from ‘Counselling on Wheels’

Background Despite theoretical support for including mental health and psychosocial support (MHPSS) with peacebuilding, few programmes in conflict-affected regions fully integrate these approaches. Aims To describe and assess preliminary o...

Why Do Most Restrained Eaters Fail in Losing Weight?: Evidence from an fMRI Study

Yanhua Su,1 Taiyong Bi,1 Gaolang Gong,2,3 Qiu Jiang,4,5 Hong Chen4,5 1Center for Mental Health Research in School of Management, Zunyi Medical University, Zunyi 563000, People’s Republic of China; 2State Key Laboratory of Cognitive Ne...

Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice

Abstract Background Fipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that exposure to FPN might induce unexpected adverse effects in the liver, reproductiv...

Clinical genetics of spondylocostal dysostosis: A mini review

Spondylocostal dysostosis is a genetic defect associated with severe rib and vertebrae malformations. In recent years, extensive clinical and molecular diagnosis advancements enabled us to identify disease-causing variants in different gene...

A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer

Lynch syndrome (LS) is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes. These mutations result in frameshift alterations, leading to the accumulation of errors within microsatellites. Individua...