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Functional Assessment of the Quality of Human Hepatocyte Preparations for Cell Transplantation

María Teresa Donato, Agustín Lahoz, Sandra Montero, Ana Bonora et al. • Cell Transplantation (2008)

Hepatocyte transplantation is an alternative therapy to orthotopic liver transplantation for the treatment of liver diseases. Good quality freshly isolated or cryopreserved human hepatocytes are needed for clinical transplantation. However,...

DOAJ Open Access (DOAJ) DOI: 10.3727/096368908787236620

So FAIR, so good

Rinaldi Lorenzo, Bonacorsi Daniele, Bozzi Concezio, Dal Pra Stefano et al. • EPJ Web of Conferences (2025)

Large international collaborations in the field of Nuclear and Subnuclear Physics have been leading the implementation of FAIR principles for managing research data. These principles are essential when dealing with large volumes of data ove...

DOAJ Open Access (DOAJ) DOI: 10.1051/epjconf/202533701140

Sensitivity Analysis and Uncertainty Quantification of Nanoparticle Deposition from Tongue Morphological Variations

Tiancheng Yang, Xiuhua Si, Jinxiang Xi • Life (2024)

The human tongue has highly variable morphology. Its role in regulating respiratory flows and deposition of inhaled aerosols remains unclear. The objective of this study was to quantify the uncertainty of nanoparticle deposition from the va...

DOAJ Open Access (DOAJ) DOI: 10.3390/life14030406

Evaluating key predictors of breast cancer through survival: a comparison of AFT frailty models with LASSO, ridge, and elastic net regularization

Senyefia Bosson-Amedenu, Emmanuel Ayitey, Francis Ayiah-Mensah, Luyton Asare • BMC Cancer (2025)

Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12885-025-14040-z

Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Marie Gaille, Marco Araneda, Clément Dubost, Clémence Guillermain et al. • BMC Medical Ethics (2020)

Abstract Background The discovery of biomarkers of ageing has led to the development of predictors of impending natural death and has paved the way for personalised estimation of the risk of death in the general population. This study inten...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12910-020-00502-5

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer (2021)

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-021-01362-2

Ozonation, electrochemical, and biological methods for the remediation of malachite green dye wastewaters: A mini review

Peter Olusakin Oladoye, Timothy Oladiran Ajiboye, Wycliffe Chisutia Wanyonyi, Elizabeth Oyinkansola Omotola et al. • Sustainable Chemistry for the Environment (2023)

The extensive usage of malachite green (MG) dyes in the fish and dye industries cause serious water pollution, leading to catastrophic effects on living organisms and the environment. In addressing the challenges of health risks related to ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.scenv.2023.100033

Metabolomic sweet spot clock predicts mortality and age-related diseases in the Canadian Longitudinal Study on Aging

Olga Vishnyakova, Joosung Min, Stephen Leach, Xiaowei Song et al. • Communications Medicine (2026)

Abstract Background Chronological age does not capture individual health or resilience. Advances in metabolomics have enabled development of molecular aging biomarkers that capture deviations between biological and chronological age, highli...

DOAJ Open Access (DOAJ) DOI: 10.1038/s43856-026-01375-2

Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)

Susan A. Kirkland, Lauren E. Griffith, Urun Erbas Oz, Mary Thompson et al. • BMC Public Health (2023)

Abstract Background Older adults have been disproportionately impacted by COVID-19 and related preventative measures undertaken during the pandemic. Given clear evidence of the relationship between loneliness and health outcomes, it is impe...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-023-15807-4

Factors Affecting High Body Weight Variability

Kyungdo Han, Mee Kyoung Kim • Journal of Obesity & Metabolic Syndrome (2023)

Background : High body weight variability (BWV) is associated with many metabolic and cardiovascular diseases in adults. The study was designed to explore the baseline characteristics associated with high BWV. Methods : Using a nationally r...

DOAJ Open Access (DOAJ) DOI: 10.7570/jomes22063

Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017

Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim et al. • Diabetes & Metabolism Journal (2023)

Background This study investigated the changes of fatty liver disease prevalence in general Korean population. Methods This study analyzed data from the Korean National Health Insurance Service from 2009 to 2017 that included individuals ag...

DOAJ Open Access (DOAJ) DOI: 10.4093/dmj.2022.0444

Active querying approach to epidemic source detection on contact networks

Martin Sterchi, Lorenz Hilfiker, Rolf Grütter, Abraham Bernstein • Scientific Reports (2023)

Abstract The problem of identifying the source of an epidemic (also called patient zero) given a network of contacts and a set of infected individuals has attracted interest from a broad range of research communities. The successful and tim...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-38282-8

Extremes of Product of Gaussian Random Variables

Džiugas Chvoinikov, Svyatoslav Novikov, Jonas Šiaulys • Axioms (2026)

We investigate the asymptotic behavior of the product of Gaussian random variables, with a focus on tail probabilities. Although sums of normal variables are well understood through classical limit theorems, their products exhibit significa...

DOAJ Open Access (DOAJ) DOI: 10.3390/axioms15060425

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Salmaan Keshavjee, Meredith B Brooks, Tom Nicholson, Viswanath Pingali • BMJ Open (2023)

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-070717

Estimated pulse wave velocity and progression to advanced cardiovascular–kidney–metabolic syndrome: a population-based longitudinal study with supportive external cross-sectional evidence

Wenjiao Zhang, Wenjiao Zhang, Wenbo Yang, Wenbo Yang et al. • Frontiers in Cardiovascular Medicine (2026)

BackgroundCardiovascular–kidney–metabolic (CKM) syndrome captures the interconnected burden of metabolic risk factors, chronic kidney disease, and cardiovascular disease. Evidence remains limited regarding simple and clinically accessible m...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2026.1875961

Effects of supplementing sweet sorghum with grapeseeds on carcass parameters, and meat quality, amino acid, and fatty acid composition of lambs

Jianxin Jiao, Ting Wang, Shanshan Li, Nana Gou et al. • Animal Bioscience (2023)

Objective Sweet sorghum is an important forage crop for ruminants, especially in low rainfall areas. Grapeseeds are an abundant by-product of wine-making and contain bioactive substances that can improve the antioxidant capacity of meat. We...

DOAJ Open Access (DOAJ) DOI: 10.5713/ab.22.0189

mtDNA variation of humpback whales in their wintering grounds of Guerrero, southern Mexican Pacific

L Medrano-González, K Audley, CS Baker, D Steel • Endangered Species Research (2024)

Here, we describe variation in mtDNA haplotypes among 22 individual humpback whales off the Guerrero coast in southern Mexico and compare this to other wintering regions in the eastern North Pacific Ocean using published data. After correct...

DOAJ Open Access (DOAJ) DOI: 10.3354/esr01332

Hydrogeochemical Characterization and Appraisal of Groundwater Quality in Yisr River Catchment, Blue Nile River Basin, Ethiopia, by Using the GIS, WQI, and Statistical Techniques

Abebaw Demelash, Abunu Atlabachew, Muralitharan Jothimani, Abel Abebe • Journal of Chemistry (2023)

Groundwater is a primary drinking, agricultural, domestic, and nondomestic water source in Ethiopia’s Yisr River watershed of the Blue Nile River basin. There has been no systematic investigation of the hydrogeochemical properties of ground...

DOAJ Open Access (DOAJ) DOI: 10.1155/2023/8199000

Identifying Key Factors Associated with the Spatiotemporal Dynamics of Fish Assemblages in Subtropical River-Type Reservoir Ecosystems: Implications for Fishery Management and Conservation

Chengjie Yin, Rongzhen Zhang, Zewen Feng, Xiaoning Shi et al. • Animals (2026)

Characterizing the spatiotemporal patterns of fish communities in subtropical river-type reservoirs provides useful baseline information for fisheries stewardship and aquatic ecosystem monitoring. This work investigated fish assemblages acr...

DOAJ Open Access (DOAJ) DOI: 10.3390/ani16182892