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Showing 20 of 1,675 academic articles

Effect of probiotics on cognitive function and cardiovascular risk factors in mild cognitive impairment and Alzheimer’s disease: an umbrella meta-analysis

Bin Xiao, Lina Fu, Zhe Yang, Guran Yu • Journal of Health, Population and Nutrition (2025)

Abstract Background This umbrella meta-analysis evaluates the effects of probiotics on cognitive function and metabolic health in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) by synthesizing findings from meta-analyses of ra...

DOAJ Open Access (DOAJ) DOI: 10.1186/s41043-025-00816-3

Sex-Related Differences in Regional Homogeneity and Intolerance of Uncertainty in Obsessive-Compulsive Disorder: A Resting-State fMRI Study

Wang A, Zhao S, Guo Q, Wu J et al. • Neuropsychiatric Disease and Treatment (2026)

Anzhen Wang,1,2 Shuai Zhao,1 Qihui Guo,3,4 Jinling Wu,1 Wenmei Fang,1 Shuang Zheng,1 Chunyan Zhu,2,5,6 Xiangyang Zhang1,3,41Affiliated Psychological Hospital of Anhui Medical University, Anhui Medical University, Hefei, People’s Republic of...

DOAJ Open Access (DOAJ)

Thematic structure of clinically oriented prefrontal function assessment and intervention research: a keyword network analysis

Jin Seok Oh, Jong Gab Ho, Jin-Hyuck Park • BMC Psychiatry (2026)

Abstract Background The prefrontal cortex (PFC) has been extensively investigated in relation to higher-order cognition, emotional regulation, and behavioural control, particularly within clinically oriented studies addressing psychiatric s...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12888-026-08277-6

Contrast Sensitivity Is Associated With Chorioretinal Thickness and Vascular Density of Eyes in Simple Early-Stage High Myopia

Xinting Liu, Yanli Wang, Xiaoxiao Ying, Fen Zhang et al. • Frontiers in Medicine (2022)

ObjectiveTo evaluate the contrast sensitivity function (CSF), chorioretinal thickness and vascular density as well as their relationships in subjects with simple early-stage high myopia.MethodsEighty-one young subjects were enrolled in this...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.847817

Psychological Components of Disease Stigma Across Illnesses: Associations with Cultural and Personal Factors

Shiming Yao, Jiajia Zhu, Yan Mu • Behavioral Sciences (2026)

Understanding public stigma against patients (also known as disease stigma)—negative attitudes or discriminatory responses toward individuals with a disease—is essential for improving health outcomes and fostering inclusive communities. In ...

DOAJ Open Access (DOAJ) DOI: 10.3390/bs16020295

Fertility and Iron Bioaccumulation in <i>Drosophila melanogaster</i> Fed with Magnetite Nanoparticles Using a Validated Method

Fernanda Pilaquinga, Sofía Cárdenas, Doris Vela, Eliza Jara et al. • Molecules (2021)

Research on nanomaterial exposure-related health risks is still quite limited; this includes standardizing methods for measuring metals in living organisms. Thus, this study validated an atomic absorption spectrophotometry method to determi...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules26092808

Evaluation of microhardness of residual dentin in primary molars following caries removal with conventional and chemomechanical techniques: An In vitro Study

A Shihab Anwar, R Krishna Kumar, V Arun Prasad Rao, N Venugopal Reddy et al. • Journal of Pharmacy and Bioallied Sciences (2017)

Background: Many patients consider removal of caries to be a very unpleasant experience. Removal of caries with conventional drill is considered traumatic mainly due to fear and anxiety of children and their parents. Minimally invasive dent...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.JPBS_148_17

Assessment of role of PPE in preventing the spread of infection among the dental surgeons: A prospective study

S Srinidhi, Sujithraj Stephen, Karthiga Mohankumar, Thomson M D'Cruz et al. • Journal of Pharmacy and Bioallied Sciences (2023)

Although there is easy accessibility of infection control measures and recommendation regarding the PPE, most of the dentists failed to practice appropriate infection control measures. The aim of the current survey was conducted to assess t...

DOAJ Open Access (DOAJ) DOI: 10.4103/jpbs.jpbs_546_22

A large deletion conferring pale green leaves of maize

Guoqi Yao, Hua Zhang, Bingying Leng, Bing Cao et al. • BMC Plant Biology (2023)

Abstract Background The structural basis of chloroplast and the regulation of chloroplast biogenesis remain largely unknown in maize. Gene mutations in these pathways have been linked to the abnormal leaf color phenotype observed in some mu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12870-023-04360-2

Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding

Yong Han, Guobin Xia, Dollada Srisai, Fantao Meng et al. • Nature Communications (2021)

Neuronal signaling has an important role in the regulation of energy expenditure and body weight, however, the underlying mechanisms are incompletely understood. Here, the authors report a AgRP-MC4R-serotonin expressing neuronal circuit tha...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-23846-x

Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival

Noela Rodriguez-Losada, Noela Rodriguez-Losada, Rune Wendelbob, M. Carmen Ocaña et al. • Frontiers in Neuroscience (2020)

Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural stem cells and ma...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2020.570409

Roles of Rap1 signaling in tumor cell migration and invasion

Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine (2017)

Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...

DOAJ Open Access (DOAJ) DOI: 10.20892/j.issn.2095-3941.2016.0086

In vivo topology converts competition for cell-matrix adhesion into directional migration

Fernanda Bajanca, Nadège Gouignard, Charlotte Colle, Maddy Parsons et al. • Nature Communications (2019)

Migrating cells encounter multiple signals such as extracellular matrix (ECM) and chemokinetic factors but how these integrate in vivo is unclear. Here, the authors report that overall control of cell-ECM adhesion by Sema3A and Sdf1 can be ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-09548-5

Effects of the Brazilian Native Fruit Jaboticaba (<i>Plinia cauliflora</i>) Peel on Inflammatory and Oxidative Stress Pathways: Insights from a Pilot Study in Hemodialysis Patients and Renal Cell Models

Ligia Soares Lima, Jessyca Sousa de Brito, Marcelo Ribeiro-Alves, Karen Salve Coutinho-Wolino et al. • Foods (2025)

Jaboticaba (Plinia cauliflora), a Brazilian native fruit rich in bioactive compounds, exhibits potent anti-inflammatory and antioxidant properties. This pilot study evaluated the effects of jaboticaba peel supplementation on inflammatory an...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods14234030

Identification of functional pathways for regenerative bioactivity of selected renal cells

Wei Sha, Timothy Bertram, Deepak Jain, Cory Brouwer et al. • Stem Cell Research & Therapy (2022)

Abstract Background Selected renal cells (SRC) are in Phase II clinical trials as a kidney-sourced, autologous, tubular epithelial cell-enriched cell-based therapy for chronic kidney disease (CKD). In preclinical studies with rodent models ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13287-022-02713-6

Can Bacillus paranthracis cause bacteremia in a T-ALL patient? WGS-based diagnosis

Serap Süzük Yıldız, Ayşegül Polat, Süleyman Yalçın, Mert Emre Ölmez et al. • Journal of Infection in Developing Countries (2025)

Introduction: Most of Bacillus spp. generally avirulent species in healthy patients, but if there is a fragile in the patient, especially their immune system, Bacillus spp. can be an agent for infections. Case Report: In this case, we rep...

DOAJ Open Access (DOAJ) DOI: 10.3855/jidc.20080

Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy

O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика (2025)

Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...

DOAJ Open Access (DOAJ) DOI: 10.17749/2070-4909/farmakoekonomika.2024.285