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Showing 20 of 881 academic articles

An Optimization via Simulation approach for the preemptive and non-preemptive multi-mode resource-constrained project scheduling problems

Parham Azimi, Naeim Azouji • International Journal of Industrial Engineering and Production Research (2017)

In this paper a novel modelling and solving method has been developed to address the so-called resource constrained project scheduling problem (RCPSP) where project tasks have multiple modes and also the preemption of activities are allowed...

DOAJ Open Access (DOAJ)

Similarity Measurement and Retrieval of Three-Dimensional Voxel Model Based on Symbolic Operator

Zhenwen He, Xianzhen Liu, Chunfeng Zhang • ISPRS International Journal of Geo-Information (2024)

Three-dimensional voxel models are widely applied in various fields such as 3D imaging, industrial design, and medical imaging. The advancement of 3D modeling techniques and measurement devices has made the generation of three-dimensional m...

DOAJ Open Access (DOAJ) DOI: 10.3390/ijgi13030089

Identification of DDIT4 as a potential prognostic marker associated with chemotherapeutic and immunotherapeutic response in triple-negative breast cancer

Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology (2023)

Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12957-023-03078-7

Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages

Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew et al. • BMC Complementary Medicine and Therapies (2020)

Abstract Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in co...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12906-020-02884-w

The Identification of a Novel Spider Toxin Peptide, Lycotoxin-Pa2a, with Antibacterial and Anti-Inflammatory Activities

Min Kyoung Shin, In-Wook Hwang, Bo-Young Jang, Kyung-Bin Bu et al. • Antibiotics (2023)

With the increasing challenge of controlling infectious diseases due to the emergence of antibiotic-resistant strains, the importance of discovering new antimicrobial agents is rapidly increasing. Animal venoms contain a variety of function...

DOAJ Open Access (DOAJ) DOI: 10.3390/antibiotics12121708

Caenorhabditis elegans Neurotoxicity Testing: Novel Applications in the Adverse Outcome Pathway Framework

Shreesh Raj Sammi, Shreesh Raj Sammi, Laura E. Jameson, Kendra D. Conrow et al. • Frontiers in Toxicology (2022)

Neurological hazard assessment of industrial and pesticidal chemicals demands a substantial amount of time and resources. Caenorhabditis elegans is an established model organism in developmental biology and neuroscience. It presents an idea...

DOAJ Open Access (DOAJ) DOI: 10.3389/ftox.2022.826488

Contribution of the Science, the Technology and the Innovation of the Universidad de Oriente to the Local Economic Revitalizing

Victor Salvador Soulary–Carracedo, Raimundo Lora–Freyre • Anuario Facultad de Ciencias Económicas y Empresariales (2015)

The main objective of the research is to design a methodology to evaluate the contribution of the science, the technology and the innovation of universities to the local economic revitalizing. The scientific novelty resides in a sequence of...

DOAJ Open Access (DOAJ)

Accessibility Assessment of Buildings Based on Multi-Source Spatial Data: Taking Wuhan as a Case Study

Xue Yang, Yanjia Cao, Anqi Wu, Mingqiang Guo et al. • ISPRS International Journal of Geo-Information (2021)

The question of whether each building of housing estate has equal access to nearby social service resources (e.g., public transportation service, catering, entertainment, etc.) is a major concern of citizens. This paper takes Wuhan as a cas...

DOAJ Open Access (DOAJ) DOI: 10.3390/ijgi10100701

A Framework to Estimate the Nutritional Value of Food in Real Time Using Deep Learning Techniques

Raza Yunus, Omar Arif, Hammad Afzal, Muhammad Faisal Amjad et al. • IEEE Access (2019)

There has been a rapid increase in dietary ailments during the last few decades, caused by unhealthy food routine. Mobile-based dietary assessment systems that can record real-time images of the meal and analyze it for nutritional content c...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2018.2879117

A Graph Neural Networks-Based Learning Framework With Hyperbolic Embedding for Personalized Tag Recommendation

Chunmei Zhang, Aoran Zhang, Li Zhang, Yonghong Yu et al. • IEEE Access (2024)

Learning high-quality representations of users, items, and tags from historical interactive data is crucial for personalized tag recommendation (PTR) systems. Currently, most PTR models are committed to learning representations from first-o...

DOAJ Open Access (DOAJ) DOI: 10.1109/ACCESS.2023.3347249

Prophylactic Absorbable Antibiotic Beads for High-risk, Implant-based Prepectoral Reconstruction

Shahnur Ahmed, MD, Jason T. C. Lee, MD, MSc, Dylan Roth, BS, Mithun Sinha, PhD et al. • Plastic and Reconstructive Surgery, Global Open (2023)

Summary:. Infections are problematic in postmastectomy implant-based reconstruction with infection rates as high as 30%. Strategies to reduce the risk of infection have demonstrated various efficacies. A prolonged course of systemic, oral a...

DOAJ Open Access (DOAJ) DOI: 10.1097/GOX.0000000000005353

Use of Point-of-care Ultrasound for Placement of a Gastric Tamponade Balloon

Patrick Minges, Martina Diaz McDermott, Jazmyn Shaw • Clinical Practice and Cases in Emergency Medicine (2025)

Case Presentation: A 30-year-old female with a history of alcoholic cirrhosis and esophageal varices presented with massive hematemesis. A gastric balloon tamponade device was subsequently placed to temporize variceal hemorrhage, and point-...

DOAJ Open Access (DOAJ) DOI: 10.5811/cpcem.24999

Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits

Mateus H. Gouveia, Amy R. Bentley, Hampton Leonard, Karlijn A. C. Meeks et al. • Scientific Reports (2021)

Abstract Genome-wide association studies (GWAS) have identified thousands of genetic loci associated with cross-sectional blood pressure (BP) traits; however, GWAS based on longitudinal BP have been underexplored. We performed ethnic-specif...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-83450-3

Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible <it>IRF1 </it>gene

Auriemma Lauren B, Shah Shaili, Linden Lara M, Henriksen Melissa A • Epigenetics & Chromatin (2012)

Abstract Background The tumor suppressor menin (MEN1) is mutated in the inherited disease multiple endocrine neoplasia type I, and has several documented cellular roles, including the activation and repression of transcription effected by s...

DOAJ Open Access (DOAJ) DOI: 10.1186/1756-8935-5-2

Prevalence and factors associated with continual opioid use among patients attending methadone clinic at Mwananyamala Hospital, Dar Es Salaam, Tanzania

Asha Shabani Ripanda, Bajarang Bal Lal Srivastava, Said Hamad Vuai, Azan A Nyundo • Forensic Science International: Reports (2019)

Trends of continual drug use while under treatment have been reported worldwide. This paper assesses opioid use among patients receiving treatment in a methadone clinic for opioid addiction. A total of 126 urine samples were analyzed using ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fsir.2019.100037

From plants to patterns: Constructing a comprehensive online strontium isoscape for Belgium (IsoBel) using high density grid mapping

Amanda Sengeløv, Giacomo Capuzzo, Sarah Dalle, Hannah F. James et al. • Geoderma (2025)

Understanding the spatial distribution of strontium isotopes in plants or other archives within a region is crucial for various fields, including archaeology, environmental studies, food sciences and forensic science. This study aims to cre...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.geoderma.2024.117123

Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

Xinyi Wei, Yanding Su, Qian Cheng, Songmao Liang et al. • Frontiers in Pharmacology (2024)

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beag...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2024.1334402