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Peculiarities of personalized selection of antipsychotic drugs for schizophrenia treatment

O.O. Khaustova, A.E. Asanova, N.O. Dzeruzhynska, M.M. Matiash • Medičnì Perspektivi (2024)

Determining the optimal antipsychotic drugs, its effective dose, duration of therapy, form, and route of administration play a key role in the treatment of schizophrenia. In addition, special attention should be paid to the effectiveness of...

DOAJ Open Access (DOAJ) DOI: 10.26641/2307-0404.2024.1.300499

The Cardiorespiratory Network in Healthy First-Degree Relatives of Schizophrenic Patients

Steffen Schulz, Jens Haueisen, Karl-Jürgen Bär, Andreas Voss • Frontiers in Neuroscience (2020)

Impaired heart rate- and respiratory regulatory processes as a sign of an autonomic dysfunction seems to be obviously present in patients suffering from schizophrenia. Since the linear and non-linear couplings within the cardiorespiratory s...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2020.00617

Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis

Peng Li, JiaLe Liu, Junjun Liu • Frontiers in Cellular and Infection Microbiology (2022)

ObjectiveWe aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease.MethodsWe performed an updated systematic review and meta-analysis of randomized controlled ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2022.915463

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists

Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology (2024)

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol31090369

The evaluation of changes in muscle strength in elderly patients with premature aging

Tatyana V. Pavlova, Kirill I. Proshchayev, Elmira E. Satarinova, Natalia B. Pilkevich et al. • Медицинский вестник Юга России (2019)

Purpose: to evaluate changes in muscle strength in elderly patients with signs of premature aging. Materials and methods: the study included 1080 people: 540 aged 44 to 54 years (mean age 49.1±2.2) and 540 at the age of 55 to 64 years (mean...

DOAJ Open Access (DOAJ) DOI: 10.21886/2219-8075-2019-10-1-59-64

Alpha-Band EEG Modulation as a Potential Aged-Related Biomarker for Biofeedback-Driven Motor–Cognitive Adaptability

Swapno Aditya, Adam Clarke, Lucy Armitage, Wing-Kai Lam et al. • Sensors (2026)

Background: Age-related changes in motor–cognitive function are associated with altered neural adaptability, particularly during tasks requiring integration of cognitive and motor processes. Dual-task paradigms are commonly used to assess s...

DOAJ Open Access (DOAJ) DOI: 10.3390/s26144575

Changes in daily living dependency and incident depressive symptoms among older individuals: findings from four prospective cohort studies

Hongwei Liu, Juxiang Yang, Gang Song, Minheng Zhang et al. • BMJ Mental Health (2025)

Background With rapid population ageing, depressive symptoms in older adults have become a pressing public health concern. While functional dependency is a known risk factor, the impact of changes in dependency over time remains unclear.Obj...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjment-2025-301749

Constructing the concept of healthy ageing and examining its association with loneliness in older adults

Ivy Yan Zhao, Mu-Hsing Ho, Stefanos Tyrovolas, Sasha Yuanjie Deng et al. • BMC Geriatrics (2023)

Abstract Background World Health Organization (WHO) has defined healthy ageing by highlighting five functional ability domains to (meet basic needs, make decisions, be mobile, build and maintain relationships, and contribute to society), wh...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-04019-5

Association of negative opinions towards telepsychiatry with its prior use and the level of geriatric psychiatry care among nursing home stakeholders

S Pirbay, MD, S Abou Kassm, MD, MPH, C Di-Maggio, MD, F Naudet, MD, PhD et al. • Archives of Gerontology and Geriatrics Plus (2025)

Objectives: Despite the benefits of geriatric telepsychiatry, the lack of support from the staff remains one of the major challenges it faces. We wanted to explore whether negative opinions towards telepsychiatry in nursing home (NH) stakeh...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100150

Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Yu -Yang Ma, Hai-Yan Li, Ruo-Nan Yao, Gong Cheng et al. • Experimental Gerontology (2025)

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112946

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway

Liwei Wu, Qiang Yu, Ping Cheng, Chuanyong Guo • PPAR Research (2021)

Background. Hepatic ischemia-reperfusion (IR) injury is one of the severe complications associated with liver surgery and leads to liver dysfunction. PPARγ is always linked with various physiologic pathways, and it can alleviate liver damag...

DOAJ Open Access (DOAJ) DOI: 10.1155/2021/6626295

Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA)

Reagan E. Garcia, Anne B. Newman, Eileen Johnson, Yujia Susanna Qiao et al. • Sensors (2025)

Fatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associated with fa...

DOAJ Open Access (DOAJ) DOI: 10.3390/s25092722

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

Impact of the Age of Cecal Material Transfer Donors on Alzheimer’s Disease Pathology in 5xFAD Mice

Francesco Valeri, Malena dos Santos Guilherme, Fuqian He, Nicolai M. Stoye et al. • Microorganisms (2021)

Alzheimer’s disease is a progressive neurodegenerative disorder affecting around 30 million patients worldwide. The predominant sporadic variant remains enigmatic as the underlying cause has still not been identified. Since efficient therap...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms9122548

Procedural Results and Long-Term Outcomes of Percutaneous Coronary Intervention for in-Stent Restenosis Chronic Total Occlusion Compared with de novo Chronic Total Occlusion

Tang G, Zheng N, Yang G, Li H et al. • International Journal of General Medicine (2021)

Guodong Tang, Naixin Zheng, Guojian Yang, Hui Li, Hu Ai, Ying Zhao, Fucheng Sun, Huiping Zhang Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences,...

DOAJ Open Access (DOAJ)

HEART Camp Connect—Promoting adherence to exercise in adults with heart failure with preserved ejection fraction

Windy W. Alonso, Sara E. Bills, Scott W. Lundgren, Steven J. Keteyian et al. • ESC Heart Failure (2025)

Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF)....

DOAJ Open Access (DOAJ) DOI: 10.1002/ehf2.15341

Having More Daughters Independently Predicts Home Discharge in Stroke Patients Admitted to Inpatient Rehabilitation Ward

Shiau-Fu Hsieh, Kuo-Liong Chien, Chu-Hao Weng, Yi-Ping Chiang • International Journal of Gerontology (2017)

Background: The predictors for failure of home discharge after post-acute inpatient stroke rehabilitation need investigation. Methods: With this retrospective case-control study conducted in a stroke rehabilitation unit in one tertiary hosp...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijge.2017.07.005

Music therapy-induced changes in salivary cortisol level are predictive of cardiovascular mortality in patients under maintenance hemodialysis

Hou YC, Lin YJ, Lu KC, Chiang HS et al. • Therapeutics and Clinical Risk Management (2017)

Yi-Chou Hou,1 Yen-Ju Lin,2 Kuo-Cheng Lu,1 Han-Sun Chiang,3 Chia-Chi Chang,4 Li-King Yang1 1Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, 2Department of Nursing, Taipei Medical Univ...

DOAJ Open Access (DOAJ)

Cloud Radiative Feedback to the Large‐Scale Atmospheric Circulation Greatly Reduces Monsoon‐Season Wet Bias Over the Tibetan Plateau in Climate Modeling

Jiarui Liu, Kun Yang, Dingchi Zhao, Peili Wu et al. • Geophysical Research Letters (2024)

Abstract Over‐estimation of summer precipitation over the Tibetan Plateau (TP) is a well‐known and persistent problem in most climate models. This study demonstrates the impact of a Gaussian Probability Density Function cloud fraction schem...

DOAJ Open Access (DOAJ) DOI: 10.1029/2024GL109180