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Green Microfluidic Method for Sustainable and High-Speed Analysis of Basic Amino Acids in Nutritional Supplements

Iva Pukleš, Csilla Páger, Nikola Sakač, Bojan Šarkanj et al. • Molecules (2024)

Amino acids (AAs) have broad nutritional, therapeutic, and medical significance and thus are one of the most common active ingredients of nutritional supplements. Analytical strategies for determining AAs are high-priced and often limited t...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules29235554

Expression Profiles of IGF1, EGF, and FGF2 Genes in Patients With Prostate Cancer in Isfahan Province, Iran

Farinaz Khosravian, Fatemeh Ketabchi, Nasrin Hadi, Faezeh Namazi et al. • Research in Molecular Medicine (2019)

Background: Prostate cancer is the second most prevalent cancer among men all over the world. Over the past 10 years, prostate cancer prevalence has increased in Iran. Growth factors have an important role in the regulation and growth of ma...

DOAJ Open Access (DOAJ)

YAP1 reactivation in cardiomyocytes following ECM remodelling contributes to the development of contractile force and sarcomere maturation

Vladimir Vinarsky, Stefania Pagliari, Bacel Aldabash, Fabiana Martino et al. • Cell Death Discovery (2025)

Abstract Cardiac diseases are fueled by extracellular matrix (ECM) remodelling. Together with the altered ECM chemical composition, the mechanical turmoil associated with ECM maladaptive remodelling in the pathological heart drives the shut...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41420-025-02793-2

Plant Virus–Derived Vectors: Applications in Agricultural and Medical Biotechnology

Peter E. Abrahamian, Rosemarie W. Hammond, John Hammond • Annual Review of Virology (2020)

Major advances in our understanding of plant viral genome expression strategies and the interaction of a virus with its host for replication and movement, induction of disease, and resistance responses have been made through the generation ...

OPENALEX DOI: https://doi.org/10.1146/annurev-virology-010720-054958

RETRACTED ARTICLE: Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus

Vassilis L. Souliotis, Konstantinos Vougas, Vassilis G. Gorgoulis, Petros P. Sfikakis • Arthritis Research & Therapy (2016)

Abstract Background Excessive autoantibody production characterizing systemic lupus erythematosus (SLE) occurs irrespective of the disease’s clinical status and is linked to increased lymphocyte apoptosis. Herein, we tested the hypothesis t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13075-016-1081-3

Specific egg yolk immunoglobulin as a promising non-antibiotic biotherapeutic product against Acinetobacter baumannii pneumonia infection

Abolfazl Jahangiri, Parviz Owlia, Iraj Rasooli, Jafar Salimian et al. • Scientific Reports (2021)

Abstract Acinetobacter baumannii is a serious health threat with a high mortality rate. We have already reported prophylactic effects of IgYs raised against OmpA and Omp34 as well as against inactivated whole-cell (IWC) of A. baumannii in a...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-81356-8

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Jiali Lv, Chen Cheng, Xinran Liu, Jinhua Song et al. • Journal of Nanobiotechnology (2025)

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03829-6

In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-Based Antiseptics against Biofilm Formed by Wound Pathogens

Grzegorz Krasowski, Adam Junka, Justyna Paleczny, Joanna Czajkowska et al. • Membranes (2021)

Chronic wounds complicated with biofilm formed by pathogens remain one of the most significant challenges of contemporary medicine. The application of topical antiseptic solutions against wound biofilm has been gaining increasing interest a...

DOAJ Open Access (DOAJ) DOI: 10.3390/membranes11010062

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

Expanding the genetic spectrum of hereditary motor sensory neuropathies in Pakistan

Asif Naveed Ahmed, Lettie E. Rawlins, Niamat Khan, Zakir Jan et al. • BMC Neurology (2024)

Abstract Background Hereditary motor and sensory neuropathy (HMSN) refers to a group of inherited progressive peripheral neuropathies characterized by reduced nerve conduction velocity with chronic segmental demyelination and/or axonal dege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-024-03882-y

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress

Hwa-Young Lee, Seung-Wook Kim, Geum-Hwa Lee, Min-Kyung Choi et al. • Scientific Reports (2017)

Abstract For this study, we examined the effects of curcumin against acute and chronic stress, paying specific attention to ROS. We also aimed to clarify the differences between acute and chronic stress conditions. We investigated the effec...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-06872-y

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

Kevin Achberger, Christopher Probst, Jasmin Haderspeck, Sylvia Bolz et al. • eLife (2019)

The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Add...

DOAJ Open Access (DOAJ) DOI: 10.7554/eLife.46188

Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males

Mahmood Rasool, Arif Malik, Ahmad Ashar Ghuman, Muhammad Abdul Basit Ashraf et al. • Frontiers in Oncology (2018)

BackgroundColorectal cancer (CRC) is the third most common type of cancer and leading cause of death worldwide. Major risk factors involved in the development of CRC are increased dietary sources, genetics, and increasing age. Purpose of th...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2018.00205

Histone deacetylase 3 deletion in alveolar type 2 epithelial cells prevents bleomycin-induced pulmonary fibrosis

Rui Xiong, Boxin Geng, Wenyang Jiang, Yong Hu et al. • Clinical Epigenetics (2023)

Abstract Background Epithelial mesenchymal transformation (EMT) in alveolar type 2 epithelial cells (AT2) is closely associated with pulmonary fibrosis (PF). Histone deacetylase 3 (HDAC3) is an important enzyme that regulates protein stabil...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13148-023-01588-5

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

Comparative Phytochemical Analysis of the Aerial Parts of <i>Pelargonium radula</i> and <i>Geranium macrorrhizum</i> Cultivated in Bulgaria Using GC-MS and HPLC

Debora Sabotinova, Petya Boycheva, Nadezhda Ivanova, Velichka Andonova et al. • Pharmaceuticals (2026)

Background: Geraniaceae species are widely used in traditional medicine. Pelargonium radula and Geranium macrorrhizum are aromatic medicinal plants traditionally used in Bulgaria for their antimicrobial, anti-inflammatory, and wound-healing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph19030346