Academic Articles & Research Papers

Assessing Phase-Locked Repetitive Transcranial Magnetic Stimulation for Treatment of Parkinson’s and Essential Tremor

Cracking rare disorders: a new minimally invasive RNA-seq protocol

Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...

BRI1 EMS SUPPRESSOR1 genes regulate abiotic stress and anther development in wheat (Triticum aestivum L.)

BRI1 EMS SUPPRESSOR1 (BES1) family members are crucial downstream regulators that positively mediate brassinosteroid signaling, playing vital roles in the regulation of plant stress responses and anther development in Arabidopsis. Important...

Evaluation of Occupational Accidents in the Forestry Sector Using Standardized Accident Rates: The Case of Türkiye

This study examines work accidents that occurred in the “Forestry and Industrial and Fuel Wood Production” sector in Türkiye between 2007 and 2024. In the research, the number of insured persons, the number of workplaces, and work accident ...

Chromosome-level genome assembly and population genomics analysis of Camellia rubituberculata provide insights into adaptation to karst habitats

Karst flora confined to isolated ‘habitat islands’ evolve specialized adaptations and unique traits, serving as ideal models for investigating adaptive evolution and species diversification mechanisms. Camellia rubituberculata, endemic to t...

Innovation and marketing strategies for PDO products: the case of “Parmigiano Reggiano” as an ingredient

Typical products can contribute to socio-economic development of their place of origin if they are able to take part in the logic of the global market. The aim of this research is to examine one type of innovation, the use of PDO products a...

Brood sex ratio in the Yellow-bellied Prinia (Prinia flaviventris)

Abstract Background The adjustment of sex ratios in birds can occur at the egg and nestling stages. Previous studies showed that the sex ratio was affected by environmental factors and parental condition; it may result in seasonal and ecosy...

Effect of Accelerated Weathering on Color and Physico-mechanical Properties of Wood-plastic Composites with Nano Titanium Dioxide

Polypropylene (PP) with black locust wood flour and maleic grafted polypropylene were used to prepare wood plastic composites (WPC) by injection molding. The effect of the addition of nano titanium oxide (nano TiO2) on the properties of the...

Physical and Chemical Effects of Different Working Gases in Coffee Brewing: A Case Study of Caffè Firenze

(1) Background: Recently, a new espresso extraction method, Caffè Firenze, has been developed, which uses gas at operating pressures of 20 bar to obtain abundant, persistent foam. The experiment aimed to evaluate the effect of using six gas...

Bone Diagenesis in Short Timescales: Insights from an Exploratory Proteomic Analysis

The evaluation of bone diagenetic phenomena in archaeological timescales has a long history; however, little is known about the origins of the microbes driving bone diagenesis, nor about the extent of bone diagenesis in short timeframes—suc...

Analysis of Cathinone Alkaloids in Khat by HPLC-Q-TOF In-source Fragmentation Multistage Mass Spectrometry

Khat is a kind of common drug plant. Many experiments have shown that the content of cathinone norpseudoephedrine and norephedrine in some varieties of Khat are similar. However, some studies showed that there are differences in the intensi...

Forensic Discrimination of White Architectural Paints via ATR FT-IR Spectroscopy and Chemometrics

The present work entailed the comparative examination and discrimination of white architectural paint samples of different brands/manufacturers. The analysis of this evidence can facilitate exhibiting a linkage between the victim, and the c...

Medico-Legal Applications of the Human Microbiome and Critical Issues Due to Environmental Transfer: A Review

Microbiome has recently seen an increase in its forensic applications. It could be employed to identify a suspect when DNA is not available; it can be used to establish postmortem interval (PMI). Furthermore, it could prove to be fundamenta...

Comparative analysis of chemical toxicological studies of pregabalin in neuropathic pain management (review)

Context: The use of pregabalin in neuropathic pain management has been increasingly associated with concerns regarding toxicity, particularly in cases of overdose, misuse, and co-exposure with central nervous system depressants. In parallel...

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Marker

The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, ...

Genome-based development of 15 microsatellite markers in fluorescent multiplexes for parentage testing in captive tigers

As one of the most endangered species, tiger (Panthera tigris) inbreeding has become an urgent issue to address. Using a microsatellite (short tandem repeat, STR) identification system, paternity testing may be helpful to avoid inbreeding i...

A pilot study of mitochondrial genomic ancestry in admixed Brazilian patients with type 1 diabetes

Abstract Interactions between multiple genes and environmental factors could be related to the pathogenesis of type 1 diabetes (T1D). The Brazilian population results from different historical miscegenation events, resulting in a highly div...

Optimization of Bacillus cereus Fermentation Process for Selenium Enrichment as Organic Selenium Source

Selenium is an essential trace element and micronutrient for human health. Application of organic selenium in plants and microorganisms as trace element supplement is attracting more and more attention. In this study, Bacillus cereus, an im...

UPLC-MS/MS Metabolomics Reveals Babao Dan’s Mechanisms in MASH Treatment with Integrating Network Pharmacology and Molecular Docking

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive disease that easily develops into cirrhosis and hepatocellular carcinoma, but its pathogenesis is not clear, and most therapeutic drugs have obvious limita...