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Showing 20 of 4,879 academic articles

A novel and accelerated method for integrated alignment and variant calling from short and long reads

Jinnan Hu, Donald Freed, Hanying Feng, Hong Chen et al. • Frontiers in Bioinformatics (2026)

BackgroundIntegrating short- and long-read sequencing technologies has become a promising approach for achieving accurate and comprehensive genomic analysis. Although short-read sequencing (Illumina, etc.) offers high base accuracy and cost...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbinf.2025.1691056

Data on gender-equitable healthcare accessibility in Northern Nigeria

Chika Yinka-Banjo, Mary Akinyemi, Olasupo Ajayi, David Tresner-Kirsch • Data in Brief (2024)

Gender equity, particularly in healthcare, has been gaining increasing attention in recent years. The goal is to ensure that everyone has equal access to quality healthcare services irrespective of age, gender, or socio-economic status. How...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2023.109979

Trends in Proportion of Delirium Among Older Emergency Department Patients in South Korea, 2017–2022

Jeongmin Moon, Seonji Kim, Daesung Lim, Ho Kyung Sung et al. • Western Journal of Emergency Medicine (2025)

Introduction: Delirium is a critical neuropsychiatric condition that surged among older adults during the coronavirus disease 2019 (COVID-19) pandemic, likely due to social isolation resulting from distancing measures. In this study we exam...

DOAJ Open Access (DOAJ) DOI: 10.5811/westjem.41507

Lessons From a Rapid Project Management Exercise in the Time of Pandemic: Methodology for a Global COVID-19 VIRUS Registry Database

Janice R Turek, Vikas Bansal, Aysun Tekin, Shuchita Singh et al. • JMIR Research Protocols (2022)

BackgroundThe rapid emergence of the COVID-19 pandemic globally collapsed health care organizations worldwide. Incomplete knowledge of best practices, progression of disease, and its impact could result in fallible care. Data on symptoms an...

DOAJ Open Access (DOAJ) DOI: 10.2196/27921

Data on the cytotoxicity of chlorogenic acid in 3D cultures of HT-29 cells

M. Daniela Vélez, Johanna Pedroza-Díaz, Gloria A. Santa-González • Data in Brief (2023)

Functional foods, beyond basic nutrition, offer health benefits to consumers thanks to the presence of bioactive compounds such as some phytochemicals [1,2]. Today, these foods are of particular interest in biomedical research due to their ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2023.109527

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

Michael Barnett, Dongang Wang, Heidi Beadnall, Antje Bischof et al. • npj Digital Medicine (2023)

Abstract Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening. While MRI is the principal tool available to neurologis...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41746-023-00940-6

Income and education predict elevated depressive symptoms in the general population: results from the Gutenberg health study

Jasmin Schlax, Claus Jünger, Manfred E. Beutel, Thomas Münzel et al. • BMC Public Health (2019)

Abstract Background Socioeconomic status (SES) has a strong association with depression or physical and mental health in general. However, as SES is a multifaceted construct these associations are not easy to explain. Further, there are sev...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-019-6730-4

Medical Informatics and eHealth

Paul J. McCullagh, Zheng Huiru, Norman D. Black, Richard John Davies et al. • Studies in health technology and informatics (2010)

Medical Informatics comprises the theoretical and practical aspects of information processing and communication, based on knowledge and experience derived from processes in medicine and healthcare. The processing takes place within computer...

OPENALEX DOI: https://doi.org/10.3233/978-1-60750-527-3-121

A Focus on Simulation in Medical Informatics

James G. Anderson • Journal of the American Medical Informatics Association (2002)

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1167 PMC: 346642

Is Medical Informatics an Art or a Science?

Reinhold Haux, Arie Hasman, A. T. McCray, Johan van der Lei • Methods of Information in Medicine (2006)

Summary Objective: To give an introduction to the special topic on ‘Medical Informatics: Art or Sciene?‘ in honor of Prof. Dr. Jan Hendrik van Bemmel. Method: Retrospective, personal review on his work. Results and Conclusions: Jan H. van B...

OPENALEX DOI: https://doi.org/10.1055/s-0038-1634130

Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Jing Jin, Yun Wang, Sixiang Liang, Qingchen Fan et al. • NeuroImage: Clinical (2025)

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2025.103902

Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial

D. Ontaneda, P. Sati, P. Raza, M. Kilbane et al. • NeuroImage: Clinical (2021)

The specificity and implementation of current MRI-based diagnostic criteria for multiple sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are eventually determined not to have the disease, with overrelianc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102834

Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors

Foley Kristie, Ip Edward, Avis Nancy E • Health and Quality of Life Outcomes (2006)

Abstract Background This paper evaluates psychometric properties of a recently developed measure focusing on the health-related quality of life (HRQL) of long-term cancer survivors, the Quality of Life in Adult Survivors scale (QLACS), in a...

DOAJ Open Access (DOAJ) DOI: 10.1186/1477-7525-4-92

Multi-label classification of fundus images based on graph convolutional network

Yinlin Cheng, Mengnan Ma, Xingyu Li, Yi Zhou • BMC Medical Informatics and Decision Making (2021)

Abstract Background Diabetic Retinopathy (DR) is the most common and serious microvascular complication in the diabetic population. Using computer-aided diagnosis from the fundus images has become a method of detecting retinal diseases, but...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12911-021-01424-x

Health-related quality of life in Chinese population with non-alcoholic fatty liver disease: a national multicenter survey

Rui Huang, Jian-Gao Fan, Jun-Ping Shi, Yi-Min Mao et al. • Health and Quality of Life Outcomes (2021)

Abstract Background Health Related Quality of Life (HRQL) is a multi-dimensional construct that can comprehensively evaluate the patient’s health status, including physical, emotional, mental and social well-being. In this study, we aimed t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-021-01778-w

Denosumab and Bisphosphonate Treatment of Osteoporosis in Renal Transplant Recipients

Serdar Şahin, Nurhan Seyahi, Sinan Trabulus, Hande Mefkure Özkaya et al. • Cerrahpaşa Medical Journal (2021)

Objective: Kidney transplant recipients are at risk of losing bone mineral density. Osteoporosis and fractures cause serious complications in renal transplant recipients. We aimed to evaluate the efficacy and safety of bisphosphonate and de...

DOAJ Open Access (DOAJ) DOI: 10.5152/cjm.2021.21039

Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality.

Tomohiro Takayama, Keina Sado, Kenji Suda, Hiroshi Tamura et al. • PLOS Digital Health (2026)

Large language models (LLMs) have been investigated for clinical documentation, with concerns about hallucinations and factual errors. Clinician review and revision of LLM-generated drafts are considered essential; however, the impact of su...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pdig.0001799

Requirements for Vitiligo Registry Design in Iran: A Qualitative Content Analysis Study

Zahra Arabkermani, Roxana Sharifian, Peivand Bastani, Azadeh Bashiri et al. • Journal of Health Sciences and Surveillance System (2025)

Background: Vitiligo is a prevalent skin disorder that has significant biological and social consequences for the affected individuals. Therefore, appropriate measures should be taken to diagnose this disease and treat patients, and powerfu...

DOAJ Open Access (DOAJ) DOI: 10.30476/jhsss.2024.101583.1884

Recommendations of the German Association for Medical Informatics, Biometry and Epidemiology for Education and Training in Medical Informatics

J. Dudeck, Wilhelm Gaus, Franz Josef Leven, Hildebrand Kunath et al. • Methods of Information in Medicine (1992)

In the fields of health care and medicine there is an immense demand for a systematic application of methods of information processing and for the use of computers. Obviously, to that end well-trained scientists and qualified personnel must...

OPENALEX DOI: https://doi.org/10.1055/s-0038-1634857