Academic Articles & Research Papers

Phosphorus runoff from Canadian agricultural land: A dataset for 30 experimental fields

Phosphorus (P) runoff from agricultural land plays a critical role in downstream water quality. This article summarizes P and sediment runoff data for both snowmelt and rainfall runoff from 30 arable fields in the Canadian provinces of Sask...

Association between social health status and health-related quality of life among community-dwelling elderly in Zhejiang

Abstract Background Population aging is an inevitable trend and previous studies have showed the relationship between social health related factors and health-related quality of life (HR-QOL) in the elderly. The objective of this study is t...

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli

Calcium/calmodulin-dependent kinase kinase 2 (CaMKK2) has been implicated in a range of conditions and pathologies from prostate to hepatic cancer. Here, we describe the expression in Escherichia coli and the purification protocol for the f...

Machine learning framework for early identification of high-spending Crohn’s disease patients using administrative claims

Objectives To develop and evaluate a machine learning (ML) model that predicts Crohn’s disease (CD) patients responsible for the top quartile of healthcare spending.Methods De-identified commercial claims (2016–2018) from ~267 000 continuou...

Online peer support for Young Onset Dementia is a promising resource, but not a panacea: a commentary from the INTERDEM Young Onset Dementia taskforce

A Virtual Reading Center Model Using Crowdsourcing to Grade Photographs for Trachoma: Validation Study

BackgroundAs trachoma is eliminated, skilled field graders become less adept at correctly identifying active disease (trachomatous inflammation—follicular [TF]). Deciding if trachoma has been eliminated from a district or if treatment strat...

Deep learning-based multimodal data fusion in bone tumor management: Advances in clinical decision support

Bone tumors (BTs)—including osteosarcoma, Ewing sarcoma, and chondrosarcoma—are rare but biologically complex malignancies characterized by pronounced heterogeneity in anatomical location, histological subtype, and molecular alterations. Re...

Medical and Health-Related Misinformation on Social Media: Bibliometric Study of the Scientific Literature

BackgroundSocial media has been extensively used for the communication of health-related information and consecutively for the potential spread of medical misinformation. Conventional systematic reviews have been published on this topic to ...

Comparative assessment of patient education content generated by five large language models on post-stroke complications: A cross-sectional study of safety, accuracy, reliability, readability, and empathy

Objective To compare the safety, accuracy, reliability, readability, and empathy of patient education content generated by five large language models (LLMs) for post-stroke complications. Methods This CHART-guided cross-sectional comparativ...

Methodology for the Positive Voices 2022 Survey of People With HIV Accessing Care in England, Wales, and Scotland: Cross-Sectional Questionnaire Study

BackgroundDue to advances in treatment, HIV is now a chronic condition with near-normal life expectancy. However, people with HIV continue to have a higher burden of mental and physical health conditions and are impacted by wider socioecono...

TURINIO RINKODAROS TYRIMŲ KAITOS TENDENCIJOS 2010-2021 M.: SISTEMINIS POŽIŪRIS

Dinamiškoje ir konkurencingoje rinkoje organizacijoms yra aktualu formuoti konkurencinį pranašumą ir kurti ryšius unikaliais, adresatams pritaikytais sprendimais. Siekiant organizacijoms konkurencinio pranašumo skaitmeniniu pavidalu, naudoj...

The thalamus and its subregions – a gateway to obsessive-compulsive disorder

Introduction Higher thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population (Boedhoe et al. 2017, Weeland et al. 2021a). Functionally distin...

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity

Abstract Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the $$S/F$...

Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review

BackgroundThe standard Fast Healthcare Interoperability Resources (FHIR) is widely used in health information technology. However, its use as a standard for health research is still less prevalent. To use existing data sources more efficien...

Real-World Evaluation of AI-Driven Diabetic Retinopathy Screening in Public Health Settings: Validation and Implementation Study

Abstract BackgroundArtificial intelligence (AI) algorithms offer an effective solution to alleviate the burden of diabetic retinopathy (DR) screening in public health settings. However, there are challenges in translating diagno...

Mobile health approaches to disease surveillance in Africa; Wellvis COVID triage tool

COVID-19 has rapidly spread across the globe and was declared a pandemic by the World Health Organization (WHO). The COVID-19 infection continues to spread across Africa. In Africa, mobile phone applications have been used for the surveilla...

Digital quality gradient and the burden of elderly depression: A spatial multi kernel SVR analysis of socio economically vulnerable groups in England

Digital infrastructure is increasingly understood as part of the contemporary built environment and as a policy-relevant area-level correlate of older adults’ mental health. Existing studies have often relied on linear models and have paid ...

G-Aligner: a graph-based feature alignment method for untargeted LC–MS-based metabolomics

Abstract Background Liquid chromatography–mass spectrometry is widely used in untargeted metabolomics for composition profiling. In multi-run analysis scenarios, features of each run are aligned into consensus features by feature alignment ...

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adole...

Medical informatics across Europe: Analysis of medical informatics scientific output in 33 European countries

OBJECTIVES: To investigate the medical informatics scientific output in 33 European countries. METHODS: Medical Subject Heading term "medical informatics" was used to identify all relevant articles published in 1998-2007 and indexed in the ...