Academic Articles & Research Papers

HEALTH TECHNOLOGIES

The use of health technologies provides better health management, anchored in equity, communication and governance in health. Technologies are conceptualized as a tool, which helps from planning to the execution of activities, and can be ap...

Statistical assessment of the learning curves of health technologies

OBJECTIVES: (1) To describe systematically studies that directly assessed the learning curve effect of health technologies. (2) Systematically to identify 'novel' statistical techniques applied to learning curve data in other fields, such a...

Purification, Characterization and Bactericidal Action of Lysozyme, Isolated from <i>Bacillus subtillis</i> BSN314: A Disintegrating Effect of Lysozyme on Gram-Positive and Gram-Negative Bacteria

In the present study, lysozyme was purified by the following multi-step methodology: salt (ammonium sulfate) precipitation, dialysis, and ultrafiltration. The lysozyme potential was measured by enzymatic activity after each purification ste...

Detection of causative agents of bacterial pneumonia in hospitalized hajj and umrah cases by multiplex real-time polymerase chain reaction

Background and Objectives: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is commonly detected in pneumonia patients who travel from the Middle East regions. Besides MERS-CoV, many other pathogenic agents cause pneumonia. Detection...

The Decellularized Calf Testis: Introducing Suitable Scaffolds for Spermatogenesis Studies

Background: Men’s infertility and lack of production of healthy and active sperm are concerns of recent years in mostcountries. Studies on the preparation of extracellular matrix (ECM) from decellularization of testis tissue and spermatogen...

Education in Medical Informatics in the Federal Republic of Germany))

The paper deals with the present situation of education at the academic level in Medical Informatics (or Medical Information Science, Electronic Data Processing applied to medicine and the health care service etc.) in the Federal Republic o...

Information Technology in Bio- and Medical Informatics

Medical Informatics and Preparedness

The terrorist attacks of September 2001 and the subsequent deliberate dissemination of anthrax have stimulated public awareness of the need in both the public health and clinical health care systems to quickly detect and respond to altered ...

Remote Consultations in England During COVID-19: Challenges in Data Quality, Linkage, and Research Validity

AbstractThe COVID-19 pandemic accelerated the adoption of remote consultations across health care, requiring rapid adjustments in service delivery. Consequently, there is an urgent need to understand the impact of remote consultations on he...

Oh brother, where art tau? Amyloid, neurodegeneration, and cognitive decline without elevated tau

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer’s disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], ...

A noncanonical AR addiction drives enzalutamide resistance in prostate cancer

Resistance to second generation anti-androgen therapies such as enzalutamide (ENZ) can emerge in prostate cancer patients. Here, the authors identify an ENZ-resistant mechanism driven by AR-dependent transcription of noncanonical targets th...

Full-thickness skin graft versus split-thickness skin graft for radial forearm free flap donor site closure: protocol for a systematic review and meta-analysis

Abstract Background The radial forearm free flap (RFFF) serves as a workhorse for a variety of reconstructions. Although there are a variety of surgical techniques for donor site closure after RFFF raising, the most common techniques are cl...

Dichloroacetate as a metabolic modulator of heart mitochondrial proteome under conditions of reduced oxygen utilization

Abstract Myocardial compensatory mechanisms stimulated by reduced oxygen utilization caused by streptozotocin-induced diabetes mellitus (DM) and treated with dichloroacetate (DCA) are presumably associated with the regulation of mitochondri...

Mapping Chinese Medical Entities to the Unified Medical Language System

Background. Chinese medical entities have not been organized comprehensively due to the lack of well-developed terminology systems, which poses a challenge to processing Chinese medical texts for fine-grained medical knowledge representatio...

Exploring barriers and enablers to implementing a digital mental health crisis risk mitigation pathway in acute paediatric care: A multi-site, exploratory mixed-methods study

Objective Children and young people (CYP) presenting in mental health crisis to acute paediatric settings represent a growing clinical and system-level challenge. These environments, primarily designed for physical healthcare, frequently la...

Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study

Background: The cornu ammonis (CA), as part of the hippocampal formation, represents a primary target region of neural degeneration in amnestic mild cognitive impairment (aMCI). Previous studies have revealed subtle structural deficits of t...

The Comparability of Men Who Have Sex With Men Recruited From Venue-Time-Space Sampling and Facebook: A Cohort Study

BackgroundRecruiting valid samples of men who have sex with men (MSM) is a key component of the US human immunodeficiency virus (HIV) surveillance and of research studies seeking to improve HIV prevention for MSM. Social media, such as Face...

Synergy between medical informatics and bioinformatics: facilitating genomic medicine for future health care

Assessing Acceptance and Intention to Use of Home Telemonitoring Among Patients with Liver Cirrhosis: Development and Initial Psychometric Validation of a TAM-Based Questionnaire

Background/Objectives: Liver cirrhosis (LC) is a major cause of morbidity and mortality requiring continuous monitoring and early recognition of clinical deterioration. Home telemonitoring is increasingly considered a supportive strategy fo...

Artificial neural network–based model for sleep quality prediction for frontline medical staff during major medical assistance

Background: The sleep quality of medical staff was severely affected during COVID-19, but the factors influencing the sleep quality of frontline staff involved in medical assistance remained unclear, and screening tools for their sleep qual...