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Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Kapil Sayal, Laura Wyatt, Louise Thomson, Grace Holt et al. • Health Technology Assessment (2025)

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

DOAJ Open Access (DOAJ) DOI: 10.3310/GJKS0519

Health Technology and Reproduction

Kathleen M. Hoeger, Terhi Piltonen • Seminars in Reproductive Medicine (2024)

Kathleen M. Hoeger, MD, MPH Terhi T. Piltonen, MD, PhD The current issue of Seminars in Reproductive Medicine is devoted to a review of the burgeoning role of health technology in the field of reproductive medicine. The guest editor for the...

OPENALEX DOI: https://doi.org/10.1055/s-0044-1791777

Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia

Julian R. Greenwood, Vanica Lacorte-Apostol, Thomas Kroj, Jonas Padilla et al. • Communications Biology (2024)

Abstract A critical step to maximize the usefulness of genome-wide association studies (GWAS) in plant breeding is the identification and validation of candidate genes underlying genetic associations. This is of particular importance in dis...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-024-06244-z

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Alex Mira, Elena Buetas, Bob T. Rosier, Danuta Mazurel et al. • Journal of Oral Microbiology (2019)

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-...

DOAJ Open Access (DOAJ) DOI: 10.1080/20002297.2019.1609838

Anticancer and anti-angiogenic activities of mannooligosaccharides extracted from coconut meal on colorectal carcinoma cells in vitro

Patthra Pason, Chakrit Tachaapaikoon, Waralee Suyama, Rattiya Waeonukul et al. • Toxicology Reports (2024)

Colorectal carcinoma (CRC) is one of the most common malignancies, though there are no effective therapeutic regimens at present. This study aimed to investigate the inhibitory effects of mannooligosaccharides extracted from coconut meal (C...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2023.12.010

Health technology, quality and safety in a learning health system

Elizabeth Marie Borycki, Andre William Kushniruk • Healthcare Management Forum (2022)

Health technology quality and safety is an important issue for health informatics (i.e. digital health) professionals. Health technologies have been used to (1) collect data that can be analyzed to improve the quality and safety of healthca...

OPENALEX cc-by-nc DOI: https://doi.org/10.1177/08404704221139383 PMC: 9975897

Issues in the Cross-National Assessment of Health Technology

Michael Drummond, Bernard S. Bloom, Guy Carrin, Alan L. Hillman et al. • International Journal of Technology Assessment in Health Care (1992)

With the growing international literature in economic evaluation and the rapid spread of new health technologies, there is a need to undertake, or at least interpret, economic evaluations on the international level. However, the ways in whi...

OPENALEX DOI: https://doi.org/10.1017/s0266462300002361

Effects of an infant formula containing a whey protein concentrate on feeding tolerance and markers of intestinal immune defense in Chinese infants

Ying Wang, Min Liu, Shaillay Kumar Dogra, Karine Vidal et al. • BMC Nutrition (2026)

Abstract Background Human milk (HM) bioactive components can have immune modulatory functions, impact the gut microbiome, and may result in functional benefits when added to infant formula (IF). In this single-arm, prospective, intervention...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40795-026-01395-0

Changes in the nonlinear and viscoelastic mechanical properties of the rat lamina cribrosa under chronic high intraocular pressure

Yuqing Wang, Liu Liu, Liu Liu, Jingxi Zhang et al. • Frontiers in Bioengineering and Biotechnology (2026)

IntroductionThe lamina cribrosa (LC) in the optic nerve head is the initial site of glaucomatous optic nerve injury. Under high intraocular pressure (IOP), the deformation of the LC compresses the retinal ganglion cell (RGC) axons passing t...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2026.1875609

Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 3; peer review: 2 approved]

Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran et al. • F1000Research (2025)

Background Breast cancer remains a significant global health concern, with early diagnosis and risk factor identification crucial for improving outcomes. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) measurements...

DOAJ Open Access (DOAJ) DOI: 10.12688/f1000research.153999.3

The Impact of Bio-Based Fertilizer Integration Into Conventional Grassland Fertilization Programmes on Soil Bacterial, Fungal, and Nematode Communities

Demi Ryan, Anna Karpinska, Patrick J. Forrestal, S. M. Ashekuzzaman et al. • Frontiers in Sustainable Food Systems (2022)

Phosphorus (P) is an essential plant macro-nutrient applied to soil in agriculture, mainly sourced from non-renewable mined phosphate-rock, of which readily accessible reserves are currently under pressure, while global food demand continue...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2022.832841

The effects of women's empowerment on the nutritional status of children in Nigeria using the 2018 demographic health survey

Ademola Akinlade, Mercy Olateju, Mayowa Salami, Oluwaseyifunmi Akinlade et al. • Babcock University Medical Journal (2026)

Objectives: The empowerment of women critically influences child nutrition in Nigeria, where malnutrition remains a major public health challenge. This study examines the relationship between dimensions of women’s empowerment, economic, edu...

DOAJ Open Access (DOAJ) DOI: 10.38029/babcockuniv.med.j..v9i3.1114

A Prospective, Randomized Trial Comparing Hydromorphone and Nalbuphine for Postcesarean Patient-Controlled Analgesia and Developing a Risk Prediction Model for Inadequate Analgesia

Zhang K, Sun J, Zhang C, Jiao B et al. • Drug Design, Development and Therapy (2025)

Kaiwen Zhang,1,* Jiaoli Sun,1,* Caixia Zhang,2 Bo Jiao,1 Wencui Zhang,1 Shangchen Yu,1 Xueqin Cao,1 Zhiqiang Zhou,1 Guanglei Zhang,1 Xianwei Zhang1 1Department of Anesthesiology and Pain Medicine,Hubei Key Laboratory of Geri...

DOAJ Open Access (DOAJ)

Use of qualitative and mixed methods research in diagnostic technology evaluation and implementation: insights from a systematic review

Caity Roleston, Umasha Ukwatte, Nia Roberts, Gail N. Hayward et al. • Diagnostic and Prognostic Research (2026)

Abstract Background Development of new diagnostic health technologies is increasing, alongside interest in how they can be implemented into health services. Evaluation of new diagnostic tests has typically consisted of technical and diagnos...

DOAJ Open Access (DOAJ) DOI: 10.1186/s41512-026-00240-z

Molecular Informatics, Chemometrics, and Sensory Omics for Constructing an Umami Peptide Cluster Library Across the Entire Lager Beer Brewing Process

Yashuai Wu, Ruiyang Yin, Wenjing Tian, Wanqiu Zhao et al. • Foods (2026)

Umami taste in lager beer not only determined body fullness and the backbone of aftertaste, but also affected the controllability and interpretability of flavor expression across the entire brewing process. Based on stage-wise sampling, pep...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods15040641

Physical, psychological and behavioural responses of aircraft occupants to volcanic emissions

C. J. Horwell, S. Ravenhall, R. Clarkson, M. Edmonds et al. • Journal of Applied Volcanology (2025)

Abstract Volcanic eruptions produce plumes of ash, gas and aerosols that present a risk to aviation at all standard flight levels. Here, we investigate atmospheric dispersal of volcanic emissions, whether and how they infiltrate aircraft, a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13617-025-00153-4

Designing mobile health technology for bipolar disorder

Jakob E. Bardram, Mads M. Frost, Károly Szántó, Maria Faurholt‐Jepsen et al. • CHI Conference on Human Factors in Computing Systems (2013)

An increasing number of pervasive healthcare systems are being designed, that allow people to monitor and get feedback on their health and wellness. To address the challenges of self-management of mental illnesses, we have developed the MON...

OPENALEX DOI: https://doi.org/10.1145/2470654.2481364

ASSESSMENT OF THE LEARNING CURVE IN HEALTH TECHNOLOGIES

Craig Robert Ramsay, Adrian Grant, Sheila A. Wallace, Paul H. Garthwaite et al. • International Journal of Technology Assessment in Health Care (2000)

OBJECTIVE: We reviewed and appraised the methods by which the issue of the learning curve has been addressed during health technology assessment in the past. METHOD: We performed a systematic review of papers in clinical databases (BIOSIS, ...

OPENALEX DOI: https://doi.org/10.1017/s0266462300103149