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An Optimal Fourth-Order Finite Difference Scheme for the Helmholtz Equation Based on the Technique of Matched Interface Boundary

Dongsheng Cheng, Jianjun Chen, Guangqing Long • Discrete Dynamics in Nature and Society (2021)

In this paper, a new optimal fourth-order 21-point finite difference scheme is proposed to solve the 2D Helmholtz equation numerically, with the technique of matched interface boundary (MIB) utilized to treat boundary problems. For the appr...

DOAJ Open Access (DOAJ) DOI: 10.1155/2021/2539272

Integrative Approach to Teaching of the Circuit Design of Analog Electron Devices in the NI ELVIS Platform

Oleg V. Stukach, Arman B. Mirmanov • Открытое образование (Москва) (2018)

Modern graduates need to work with electronic devices. On laboratory work, students conduct experiments to solve practical problems of researching real problems that arise in the design and operation of electronic devices. However, the shor...

DOAJ Open Access (DOAJ) DOI: 10.21686/1818-4243-2018-4-4-11

Clustering Ensemble Joint Similarity Recommendation Algorithm Optimized by Improved Bee Colony

WANG Yan, WANG Congying, SHEN Yanmei • Jisuanji gongcheng (2020)

The collaborative filtering algorithm is widely used in the field of recommendation because of its good recommendation effect,which nonetheless is significantly reduced when the data is sparse and from a cold start.In this case,in order to ...

DOAJ Open Access (DOAJ) DOI: 10.19678/j.issn.1000-3428.0055939

A Rare Big Chinese Family With Thrombocytopenia 2: A Case Report and Literature Review

Chengning Tan, Limeng Dai, Zhengqiong Chen, Wuchen Yang et al. • Frontiers in Genetics (2020)

Thrombocytopenia 2 (THC2) is one of the most prevalent forms of inherited thrombocytopenia. It is caused by a heterogeneous group of ANKRD26 gene mutation and shows a heterogeneous clinical and laboratory characteristics. We present a big C...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2020.00340

Post-Fire Abundance Trajectories of Bird Species and Functional Groups Within an Atlantic–Mediterranean Ecotone

Fernando García-Fernández, Jesús Domínguez, Alberto Gil-Carrera, Luis Tapia et al. • Fire (2026)

The Atlantic–Mediterranean ecotone of northwestern Iberia is one of the most fire-prone regions in Europe, yet post-fire avian dynamics there remain poorly documented. To characterise short- to mid-term post-fire avian trajectories in this ...

DOAJ Open Access (DOAJ) DOI: 10.3390/fire9090400

Genetic analysis of suicide: a sample study in Tuscany (Central Italy)

Martina Focardi, Barbara Gualco, Vilma Pinchi, Norelli Gian-Aristide et al. • Forensic Sciences Research (2022)

Many studies have examined the genetic contribution to suicide. However, data on suicide in the Italian population are scarce. We therefore aimed to address this gap by investigating a cohort of 111 Italians for whom a verdict of suicide ha...

DOAJ Open Access (DOAJ) DOI: 10.1080/20961790.2020.1835156

Generation of human induced pluripotent stem cell line MHHi040-A from a female Fabry disease patient carrying c.644A>G missense mutation

Carla Borisch, Nick Heise, Kristina Sonnenschein, Nataliya Di Donato et al. • Stem Cell Research (2026)

Fabry disease (FD) is an X-linked, monogenic lysosomal storage disorder, caused by mutations in the GLA gene. GLA encodes the lysosomal hydrolase alpha-galactosidase A and enzyme deficiency leads to accumulation of its substrate globotriaos...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.scr.2026.104064

Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications

Liu Y, Song X, Wu M, Wu J et al. • Cancer Management and Research (2020)

Yusi Liu, Xue Song, Moli Wu, Jiao Wu, Jia Liu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, People’s Republic of ChinaCorre...

DOAJ Open Access (DOAJ)

The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

Katja Niesel, Michael Schulz, Julian Anthes, Tijna Alekseeva et al. • EMBO Molecular Medicine (2021)

Abstract The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes. Desp...

DOAJ Open Access (DOAJ) DOI: 10.15252/emmm.202013412

Causal relationship between genetic-predicted uric acid and cervical cancer risk: evidence for nutritional intervention on cervical cancer prevention

Chunge Cao, Dajun Cai, Hao Liu, Xia Zhang et al. • Frontiers in Nutrition (2024)

IntroductionThe relationship between serum uric acid (SUA) and cervical cancer is inconclusive. This study aims to investigate the causal relationship between SUA levels and cervical cancer incidence, and to evaluate the potential role of n...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2024.1464046

HumanViCe: Host ceRNA network in virus infected cells in human

Suman eGhosal, Shaoli eDas, Rituparno eSen, Jayprokas eChakrabarti et al. • Frontiers in Genetics (2014)

Host-virus interaction via host cellular components has been an important field of research in recent times. RNA interference mediated by short interfering RNAs and microRNAs (miRNA), is a widespread anti-viral defence strategy. Importantly...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2014.00249

Effectiveness of Ultrasound Imaging in Assessing the Palpation Skills of Rotating Physicians

Peizhen Huang, Bin Zheng, Shan Liu, Lin Xu et al. • Frontiers in Genetics (2022)

As an important means of physical examination, palpation is usually limited to the physical examination before surgery and used as an auxiliary method for disease diagnosis in the field of surgery. In practice, palpation is also used in eve...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2022.894716

Functional annotation of the human retinal pigment epithelium transcriptome

Gorgels Theo GMF, van der Spek Peter J, Verkerk Annemieke JMH, Essing Anke HW et al. • BMC Genomics (2009)

Abstract Background To determine level, variability and functional annotation of gene expression of the human retinal pigment epithelium (RPE), the key tissue involved in retinal diseases like age-related macular degeneration and retinitis ...

DOAJ Open Access (DOAJ) DOI: 10.1186/1471-2164-10-164

Monogenic obesity due to MC4R deficiency: lessons from a multigenerational case

Eleni Z. Giannopoulou, Stefanie Zorn, Melanie Schirmer, Stephanie Brandt-Heunemann et al. • Molecular and Cellular Pediatrics (2026)

Abstract Background Melanocortin 4 receptor (MC4R) deficiency is the most common monogenic cause of obesity, yet remains underdiagnosed. Patients with monogenic obesity often undergo a frustrating diagnostic and therapeutic odyssey of years...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40348-025-00214-z

Abnormal X : autosome ratio, but normal X chromosome inactivation in human triploid cultures

Norwood Thomas H, Luo Ping, Varadarajan Kartik R, Gartler Stanley M et al. • BMC Genetics (2006)

Abstract Background X chromosome inactivation (XCI) is that aspect of mammalian dosage compensation that brings about equivalence of X-linked gene expression between females and males by inactivating one of the two X chromosomes (Xi) in nor...

DOAJ Open Access (DOAJ) DOI: 10.1186/1471-2156-7-41

Genetics of MDS

Seishi Ogawa • Blood (2019)

Our knowledge about the genetics of myelodysplastic syndromes (MDS) and related myeloid disorders has been dramatically improved during the past decade, in which revolutionized sequencing technologies have played a major role. Through inten...

OPENALEX Open Access DOI: https://doi.org/10.1182/blood-2018-10-844621 PMC: 6587668

Reproduction and the Reduction of Genetics

James R. Griesemer • Cambridge University Press eBooks (2000)

In this essay I develop a new, unified perspective on genetics, development, and reproduction. I suggest a heuristic use of theory reduction to address an issue of contemporary theoretical importance: the framing of a theory of developmenta...

OPENALEX DOI: https://doi.org/10.1017/cbo9780511527296.013