Academic Articles & Research Papers

Strategic Health Technology Incorporation

Astaxanthin biofortification enhances tobacco tolerance to lead stress through boosting antioxidant defense, reducing Pb accumulation, and modulating detoxification pathways

Introduction: Heavy metal pollution including lead (Pb) has become one of the serious global issues threatening food security, human health, and the ecosystem. Exogenous application of astaxanthin (ATX), a potent natural antioxidant, has be...

Recent advances in benzo[a]phenoxazine-based fluorescent probes: a review and perspectives

Benzo[a]phenoxazine (BPO) based molecules have been recently emerged as a new class of near-infrared (NIR) fluorophore for image-guided diagnosis in cancer research. The successful application of BPOs as NIR fluorophore in biomedical resear...

MBOAT7-TMC4 rs641738 Is Not Associated With the Risk of Hepatocellular Carcinoma or Persistent Hepatitis B Infection

ObjectiveA hot genetic variant, rs641738 within the membrane-bound O-acyltransferase domain containing 7(MBOAT7) and transmembrane channel-like 4 (TMC4), was recently reported to be associated with several liver diseases. However, the resul...

Hypermethylated PCDHGB7 as a universal cancer only marker and its application in early cervical cancer screening

Genome-wide association analysis uncovers rice blast resistance alleles of Ptr and Pia

Abstract A critical step to maximize the usefulness of genome-wide association studies (GWAS) in plant breeding is the identification and validation of candidate genes underlying genetic associations. This is of particular importance in dis...

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Respiratory disease: A bovine model for respiratory syncytial virus vaccines Researchers have produced a vaccine that protects against bovine respiratory syncytial virus (bRSV) in calves, with implications for humans. An international team ...

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-...

Anticancer and anti-angiogenic activities of mannooligosaccharides extracted from coconut meal on colorectal carcinoma cells in vitro

Colorectal carcinoma (CRC) is one of the most common malignancies, though there are no effective therapeutic regimens at present. This study aimed to investigate the inhibitory effects of mannooligosaccharides extracted from coconut meal (C...

Clinical yarning with Aboriginal and/or Torres Strait Islander peoples—a systematic scoping review of its use and impacts

Abstract Objectives To explore how clinical yarning has been utilised as a health intervention for Aboriginal and/or Torres Strait Islander peoples and if there are any reported impacts yarning might have on health outcomes. Study design Sy...

Add-On Selective Estrogen Receptor Modulators for Methadone Maintenance Treatment

Methadone maintenance treatment (MMT) remains the cornerstone for the management of opiate abuse. However, MMT can be associated with complex factors, including complications during the tolerance phase, the inability of some patients to mai...

Effectiveness of Back care education Programme among school children: a systematic review of randomized controlled trials

Abstract Study design Systematic review of Randomised controlled trials. Objectives With the increasing incidence of back pain among children and its untold implications to their future, back education tailored in an effective way would be ...

The clinical effectiveness and cost-effectiveness of gemcitabine for metastatic breast cancer: a systematic review and economic evaluation

Strategy for health technology.

This paper presents a conceptual framework for improved management to support a pilot demonstration for the U.S. Department of Health, Education, and Welfare's new Office of Health Technology, and reports findings and implications of a rece...

Health technology, quality and safety in a learning health system

Health technology quality and safety is an important issue for health informatics (i.e. digital health) professionals. Health technologies have been used to (1) collect data that can be analyzed to improve the quality and safety of healthca...

Barriers and facilitators to utilizing digital health technologies by healthcare professionals

Abstract Digital technologies change the healthcare environment, with several studies suggesting barriers and facilitators to using digital interventions by healthcare professionals (HPs). We consolidated the evidence from existing systemat...

Patient Involvement in Health Technology Assessment

A taxonomy of model structures for economic evaluation of health technologies

Models for the economic evaluation of health technologies provide valuable information to decision makers. The choice of model structure is rarely discussed in published studies and can affect the results produced. Many papers describe good...

Health technology assessment: a framework

In a time where there is growing pressure on healthcare budgets, there is increased scrutiny of new health technologies, their effectiveness, safety and costs.1 It is in this context that Health Technology Assessment (HTA) has become increa...

Health technology innovations

The global pandemic has drastically impacted older adults in numerous ways (e.g., loneliness; age discrimination; mental and physical health; limited access to traditional health care).On the other hand, it may have accelerated the general ...