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Academic Articles & Research Papers
Showing 20 of 7,342 academic articles
Massimo Fioranelli, Maria Grazia Roccia, Bianca Przybylek, Francesca Romana Sconci et al. • Beni-Suef University Journal of Basic and Applied Sciences
(2024)
Abstract Background The inflammatory response is fundamental to the maintenance of an organism’s physiological homeostasis. Inflammation is controlled by a series of biological events driven by specific inflammatory molecules. When inflamma...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s43088-024-00506-9
Yasushi Hirasawa, Aiko Muramatsu, Yoshio Suzuki, Tadashi Nagamatsu • Journal of Pharmacological Sciences
(2006)
To elucidate the involvement of cyclooxygenase (COX) in degradation of aggregated protein in diabetic glomeruli, we used streptozotocin (STZ)-induced diabetic mice and aggregated bovine serum albumin (a-BSA) as a model protein. There was a ...
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Open Access (DOAJ)
DOI: 10.1254/jphs.FPJ06010X
Man Luo, Man Luo, Man Luo, Jiang Zhu et al. • Frontiers in Pharmacology
(2025)
BackgroundDrug repurposing has emerged as a promising approach for discovering novel anticancer therapeutics. In this study, we systematically investigated the antitumor potential of fedratinib, a JAK2 inhibitor approved for myelofibrosis, ...
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Open Access (DOAJ)
DOI: 10.3389/fphar.2025.1689663
Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis
(2024)
Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...
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Open Access (DOAJ)
DOI: 10.1016/j.rpth.2024.102615
Yongxiao Li, Wanting Xu, Xinpei Wang, Ruizhi Lai et al. • Bioengineering
(2024)
In this study, we advance our exploration of Apolipoprotein A-I (apoA-I) peptide analogs (APAs) for their application in nanodisc (ND) assembly, focusing on the dynamic conformational characteristics and the potential for drug delivery. We ...
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Open Access (DOAJ)
DOI: 10.3390/bioengineering11030245
Isabel Gómez-Betancur, Vedanjali Gogineni, Andrea Salazar-Ospina, Francisco León • Molecules
(2019)
Snakebite envenomation is a life-threatening disease that was recently re-included as a neglected tropical disease (NTD), affecting millions of people in tropical and subtropical areas of the world. Improvement in the therapeutic approaches...
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Open Access (DOAJ)
DOI: 10.3390/molecules24183276
Xinpeng Jiang, Shanshan Gu, Di Liu, Lili Zhao et al. • Frontiers in Microbiology
(2018)
Aims:Lactobacillus strains have protective effects against heavy metals while relieving oxidative stress and modulating the immune response. Mechanisms that ameliorate heavy metal toxicity and the relationship between probiotics and gut bar...
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Open Access (DOAJ)
DOI: 10.3389/fmicb.2018.02425
Abdullah Al Mamun, Yanqing Wu, Ilma Monalisa, Chang Jia et al. • Journal of Advanced Research
(2021)
Background: Currently, spinal cord injury (SCI) is a pathological incident that triggers several neuropathological conditions, leading to the initiation of neuronal damage with several pro-inflammatory mediators' release. However, pyroptosi...
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Open Access (DOAJ)
DOI: 10.1016/j.jare.2020.08.004
Ali Taheri, Ruba Almasri, Anthony Wignall, Felicia Feltrin et al. • Pharmaceutics
(2025)
Background/Objectives: Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystalli...
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Open Access (DOAJ)
DOI: 10.3390/pharmaceutics17101289
Jiashen Tang, Jiashen Tang, Connor A. Roncaioli, Andrew M. Edmonds et al. • Frontiers in Quantum Science and Technology
(2025)
Ensembles of nitrogen-vacancy (NV) centers in diamond are versatile quantum sensors with broad applications in the physical and life sciences. The concentration of neutral substitutional nitrogen ([Ns0]) strongly influences NV electronic sp...
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Open Access (DOAJ)
DOI: 10.3389/frqst.2025.1701548
Yang Yue, Jian Zhao, Jiangbing Du, Zhaohui Li • Sensors
(2021)
It is well known that optical fiber communications support the global communication networks nowadays, which originates from Charles K [...]...
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Open Access (DOAJ)
DOI: 10.3390/s21061969
Abdulaziz Khalid Alsharidi, Ahmet Bekir • Axioms
(2025)
The paper consists of various types of wave solutions for the truncated M-fractional Bateman–Burgers equation, a significant mathematical physics equation. This model describes the nonlinear waves and solitons in different physical fields s...
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Open Access (DOAJ)
DOI: 10.3390/axioms14080617
Lucrezia Catanzaro, Marcello Condorelli, Mario Pulvirenti, Luisa D’urso et al. • Nanomaterials
(2026)
Noble metal nanostructures provide versatile platforms for light manipulation through localized surface plasmon resonances (LSPRs). Among them, triangular silver nanoplates (AgNPTs) exhibit strong field-enhancement and spectral tunability, ...
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Open Access (DOAJ)
DOI: 10.3390/nano16080486
Zelin Zhang, Yu Qin, Jie Zhu, Caoyuan Wang et al. • Micromachines
(2024)
We optimized and fabricated an ultra-bend-resistant 4-core simplex cable (SXC) employing 4-core multicore fiber (MCF) suitable for short-reach dense spatial division multiplexing (DSDM) optical transmission in the O-band. The characteristic...
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Open Access (DOAJ)
DOI: 10.3390/mi15010108
Daniel Smith, Soon Hock Ng, Molong Han, Tomas Katkus et al. • Engineering Proceedings
(2023)
We show that single-pulse burst fabrication will produce a flatter and smoother profile of axicons milled on sapphire compared to pulse overlapped fabrication which results in a damaged and much rougher surface. The fabrication of large-are...
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Open Access (DOAJ)
DOI: 10.3390/HMAM2-14147
Qi Wu, Zhaopeng Xu, Yixiao Zhu, Yikun Zhang et al. • Photonics
(2023)
Driven by emerging technologies such as the Internet of Things, 4K/8K video applications, virtual reality, and the metaverse, global internet protocol traffic has experienced an explosive growth in recent years. The surge in traffic imposes...
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Open Access (DOAJ)
DOI: 10.3390/photonics10091001
Xiaoying He, Anqi Hu, Xia Guo • IEEE Photonics Journal
(2019)
Graphene and hBN as two-dimensional materials with excellent optical properties can be combined with other materials. In this paper, graphene and hBN is sequentially deposited on the surface of the silicon-core fiber to serve as transverse ...
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Open Access (DOAJ)
DOI: 10.1109/JPHOT.2019.2946201
Zhenyue Chen, Yi Chen, Irmak Gezginer, Qingxiang Ding et al. • Light: Science & Applications
(2025)
Abstract A critical gap currently exists in systematic understanding and experimental validation of the role of astrocytes in neurovascular coupling and their functional links with other brain cells. Despite a broad selection of functional ...
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Open Access (DOAJ)
DOI: 10.1038/s41377-025-02003-9
Jinnan Zhang, Lingmei Ai, Xin Yan, Yao Wu et al. • Nanoscale Research Letters
(2018)
Abstract The photovoltaic performance of axial and radial pin junction GaAs nanocone array solar cells is investigated. Compared with the cylinder nanowire arrays, the nanocone arrays not only improve the whole optical absorption but more i...
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Open Access (DOAJ)
DOI: 10.1186/s11671-018-2727-7
Zhaokun Zhou, Helen Miller, Adam J.M. Wollman, Mark C. Leake • Photonics
(2015)
We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and man...
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Open Access (DOAJ)
DOI: 10.3390/photonics2030758