Academic Articles & Research Papers

European Law and New Health Technologies

Health is a matter of fundamental importance in European societies, both as a human right in itself, and as a factor in a productive workforce and therefore a healthy economy. New health technologies promise improved quality of life for pat...

TOWARD TRANSPARENCY IN HEALTH TECHNOLOGY ASSESSMENT

OBJECTIVES: As an initiative of the International Network of Agencies for Health Technology Assessment (INAHTA), a checklist for assessment reports was developed as a means of improving transparency and consistency in HTA. METHODS: Preparat...

Ethical analysis to improve decision-making on health technologies

Health technology assessment (HTA) is the multidisciplinary study of the implications of the development, diffusion and use of health technologies. It supports health-policy decisions by providing a joint knowledge base for decision-makers....

HEALTH TECHNOLOGY ASSESSMENT IN EUROPE

This paper discusses the challenges facing health technology assessment (HTA) in Europe, based on an explicit analysis of the characteristics of an "optimal" HTA system. It has three objectives: a) to elaborate an explicit system of policy ...

Future of Health Technology

Health Technology: Past and Future Developments in the Health Technology Sector

An Equity Framework for Health Technology Assessments

Despite the inclusion of equity in the design of many health care systems, pragmatic tools for considering equity systematically, alongside the efficiency categories of cost-effectiveness in health technology assessment (HTA), remain underd...

European network for Health Technology Assessment, EUnetHTA: Planning, development, and implementation of a sustainable European network for Health Technology Assessment

OBJECTIVES: The European network on Health Technology Assessment (EUnetHTA) aimed to produce tangible and practical results to be used in the various phases of health technology assessment and to establish a framework and processes to suppo...

Design and evaluation guidelines for mental health technologies

It is increasingly recognised that technology has the potential to significantly improve access, engagement, effectiveness and affordability of treatment for mental health problems. The development of such technology has recently become the...

LADS: a powerful vaccine platform for cancer immunotherapy and prevention

Abstract Background The intracellular bacterium Listeria monocytogenes is an attractive vector for cancer immunotherapy as it can effectively deliver tumor antigens to antigen-presenting cells, leading to a robust antitumor response. Result...

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS>0) is often missing or inaccurate in re...

Melanopsin and Cone Photoreceptor Inputs to the Afferent Pupil Light Response

Background: Retinal photoreceptors provide the main stage in the mammalian eye for regulating the retinal illumination through changes in pupil diameter, with a small population of melanopsin-expressing intrinsically photosensitive retinal ...

Design and Optimization of Trastuzumab-Functionalized Nanolipid Carriers for Targeted Capecitabine Delivery: Anti-Cancer Effectiveness Evaluation in MCF-7 and SKBR3 Cells

Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...

Cross-national validation of the MHQoL: psychometric evaluation and open-source tools for assessing mental health quality of life

Objectives To validate the cross-national psychometric properties of the Mental Health Quality of Life questionnaire (MHQoL) and to develop an open-source toolbox for its scoring, transformation and presentation.Design Secondary analysis of...

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not ...

Preferences for and drivers of adult vaccination clinic site selection: A cross-sectional study in 30 provinces in China

Focusing on vaccines available to adults and not in the immunization schedule, this study investigates the preferences and factors influencing adults in selecting vaccination clinic locations. It aims to provide strategic insights for boost...

Influence of Different Disinfectants on Surface Hardness of Heat-Polymerized Acrylic Resins utilized for Orthodontic Appliance

Heat-polymerized resins are common substances utilized for construction of removable dental prostheses (i.e. Orthodontic appliances). Such materials should have appropriate physical properties. The use of disinfectant solutions might influe...

Comparative Study for Selective Lithium Recovery via Chemical Transformations during Incineration and Dynamic Pyrolysis of EV Li-Ion Batteries

Selective leaching of Li from spent LIBs thermally pretreated by pyrolysis and incineration between 400 and 700 °C for 30, 60, and 90 min followed by water leaching at high temperature and high L/S ratio was examined. During the thermal pre...

Plasma Non-Enzymatic Antioxidant Capacity (NEAC) in Relation to Dietary NEAC, Nutrient Antioxidants and Inflammation-Related Biomarkers

(1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-NEAC, respectively) and the body’s antioxidant and inflammation response. Our aim was to explore these assoc...

A living archive of JEDI curriculum reform in graduate STEMM education

Educational reform has become an important response to intersecting sociopolitical pressures, not only in the broader field of education but also in graduate education in science, technology, engineering, math, and medicine (STEMM), where s...