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Trends in Proportion of Delirium Among Older Emergency Department Patients in South Korea, 2017–2022

Jeongmin Moon, Seonji Kim, Daesung Lim, Ho Kyung Sung et al. • Western Journal of Emergency Medicine (2025)

Introduction: Delirium is a critical neuropsychiatric condition that surged among older adults during the coronavirus disease 2019 (COVID-19) pandemic, likely due to social isolation resulting from distancing measures. In this study we exam...

DOAJ Open Access (DOAJ) DOI: 10.5811/westjem.41507

Estimation of the probability of daily fluctuations of incidence of COVID-19 according to official data

Andrey Gerasimov, Elena Galkina, Elena Danilova, Irina Ikonnikova et al. • PeerJ (2021)

When studying the dynamics of morbidity and mortality, one should not limit ourselves to analyzing general trends. Interesting information can be obtained from the analysis of deviations in morbidity and mortality from the general dynamics....

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.11049

Lessons From a Rapid Project Management Exercise in the Time of Pandemic: Methodology for a Global COVID-19 VIRUS Registry Database

Janice R Turek, Vikas Bansal, Aysun Tekin, Shuchita Singh et al. • JMIR Research Protocols (2022)

BackgroundThe rapid emergence of the COVID-19 pandemic globally collapsed health care organizations worldwide. Incomplete knowledge of best practices, progression of disease, and its impact could result in fallible care. Data on symptoms an...

DOAJ Open Access (DOAJ) DOI: 10.2196/27921

Medical Informatics

D A Lindberg • JAMA (1996)

Since our review last year,13 applications of medical informatics have seen substantial progress: computer-based patient records,2telemedicine,3and electronic biomedical publishing.4The evidence lies not only in technical advances but also ...

OPENALEX DOI: https://doi.org/10.1001/jama.1996.03530470049029

Relating increasing hantavirus incidences to the changing climate: the mast connection

Maes Piet, Vandamme Anne-Mieke, Barrios José M, Ducoffre Geneviève et al. • International Journal of Health Geographics (2009)

Abstract Background Nephropathia epidemica (NE), an emerging rodent-borne viral disease, has become the most important cause of infectious acute renal failure in Belgium, with sharp increases in incidence occurring for more than a decade. B...

DOAJ Open Access (DOAJ) DOI: 10.1186/1476-072X-8-1

Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Jeanette Zanker, Daniela Hüser, Adrien Savy, Sara Lázaro-Petri et al. • Frontiers in Molecular Neuroscience (2023)

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2023.1280556

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

Kejie Mou, Mohnad Abdalla, Dong Qing Wei, Muhammad Tahir Khan et al. • Informatics in Medicine Unlocked (2021)

Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one of the structural proteins; plays a critical role in v...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.imu.2021.100675

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

Pasquale Ambrosino, Ilenia Calcaterra, Antonio Molino, Pasquale Moretta et al. • Biomedicines (2021)

Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines9080957

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Raife Dilek Turan, Cihan Tastan, Derya Dilek Kancagi, Bulut Yurtsever et al. • Scientific Reports (2021)

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-95086-4

Isolation, characterization, and genomic analysis of a novel phage WSPA with lytic activity against Serratia marcescens

Lijuan Li, Kunkun Li, Yu Mi, Xiumei Wu et al. • Microbiology Spectrum (2025)

ABSTRACT Serratia marcescens is an established pathogen implicated in hospital-acquired infections and is notorious for its propensity to form biofilms on medical devices, leading to persistent environmental contamination and increased infe...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02716-24

Epstein–Barr Virus-Induced Metabolic Rearrangements in Human B-Cell Lymphomas

Pier P. Piccaluga, Pier P. Piccaluga, Pier P. Piccaluga, Alessandra Weber et al. • Frontiers in Microbiology (2018)

Tumor metabolism has been the object of several studies in the past, leading to the pivotal observation of a consistent shift toward aerobic glycolysis (so-called Warburg effect). More recently, several additional investigations proved that...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2018.01233

Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of IK(M) or IK(DR) and in the Stimulation of IMEP

Wei-Ting Chang, Wei-Ting Chang, Wei-Ting Chang, Ping-Yen Liu et al. • Frontiers in Pharmacology (2020)

Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide analogs, has been particularly tailored for treatment of coronavirus infections. However, to which extent RDV is able to modify various types of membrane ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2020.01091

Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure

Gabriela Brzuska, Gabriela Pastuch-Gawolek, Monika Krawczyk, Boguslaw Szewczyk et al. • Pharmaceuticals (2020)

Tick-borne encephalitis virus (TBEV) transmitted by ticks is a pathogen of great medical importance. As still no effective antiviral treatment is available, in the present study, a series of uridine glycoconjugates containing amide or/and 1...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph13120460

Plant Virus–Derived Vectors: Applications in Agricultural and Medical Biotechnology

Peter E. Abrahamian, Rosemarie W. Hammond, John Hammond • Annual Review of Virology (2020)

Major advances in our understanding of plant viral genome expression strategies and the interaction of a virus with its host for replication and movement, induction of disease, and resistance responses have been made through the generation ...

OPENALEX DOI: https://doi.org/10.1146/annurev-virology-010720-054958

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

Bruce Nzimande, John P. Makhwitine, Nompumelelo P. Mkhwanazi, Sizwe I. Ndlovu • Viruses (2023)

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a significant concern. Therefore, there is a continuous ne...

DOAJ Open Access (DOAJ) DOI: 10.3390/v15051039

Medical Biotechnology

Firdos Alam Khan • CRC Press eBooks (2020)

Biotechnology has many applications in medicine. While dealing with diseases, biotechnology tools and techniques have been used in the prevention, diagnosis, and cure of diseases. Through human genetics, biotechnology has found use in genet...

OPENALEX DOI: https://doi.org/10.1201/9781003024750-9