Academic Articles & Research Papers

UAC-Net: a unified multi-task network with aggregated contextual attention and cross-layer fusion for brain tumor segmentation and classification.

Simulating a virtual tumor board with large language models: a pilot study in NSCLC patients receiving immunotherapy.

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

Abstract In recent years, long non-coding RNA (lncRNA) research has identified essential roles of these transcripts in virtually all physiological cellular processes including tumorigenesis, but their functions and molecular mechanisms are ...

Data Efficient Vision Transformer Based Model for Brain Tumor Classification in MRI

Accurate detection of brain tumors at early stages is crucial for clinical diagnosis and treatment planning. Magnetic Resonance Imaging (MRI) is the most popular method due to its soft-tissue contrast and spatial resolution. However, manual...

Brain tumor grading based on Neural Networks and Convolutional Neural Networks

This paper studies brain tumor grading using multiphase MRI images and compares the results with various configurations of deep learning structure and baseline Neural Networks. The MRI images are used directly into the learning machine, wit...

Connectomic insights into the impact of 1p/19q co-deletion in dominant hemisphere insular glioma patients

ObjectivesThis study aimed to elucidate the influences of 1p/19q co-deletion on structural connectivity alterations in patients with dominant hemisphere insular diffuse gliomas.MethodsWe incorporated 32 cases of left insular gliomas and 20 ...

Assessment of algorithmic performance in PET-CT segmentation of solitary lung tumors.

A Preliminary Study on the Auto-Segmentation of Targets and Organs at Risk in Pediatric Total Marrow and Lymphoid Irradiation

Introduction Leukemia is one of the most prevalent cancers in children. The use of total marrow and lymphoid irradiation (TMLI) via helical tomotherapy (TOMO) as a conditioning regimen prior to bone marrow transplant (BMT) has been widely a...

A Sex-Specific Platelet Switch Controls Anti-Tumor Immunity in Glioblastoma.

Multimodal artificial intelligence for subepithelial lesion classification and characterization: a multicenter comparative study (with video)

Abstract Background Subepithelial lesions (SELs) present significant diagnostic challenges in gastrointestinal endoscopy, particularly in differentiating malignant types, such as gastrointestinal stromal tumors (GISTs) and neuroendocrine tu...

Feasibility and effectiveness of automatic deep learning network and radiomics models for differentiating tumor stroma ratio in pancreatic ductal adenocarcinoma

Abstract Objective This study aims to compare the feasibility and effectiveness of automatic deep learning network and radiomics models in differentiating low tumor stroma ratio (TSR) from high TSR in pancreatic ductal adenocarcinoma (PDAC)...

Prediction of lymph node metastasis in papillary thyroid carcinoma using non-contrast CT-based radiomics and deep learning with thyroid lobe segmentation: A dual-center study

Objectives: This study aimed to develop a predictive model for lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) patients by deep learning radiomic (DLRad) and clinical features. Methods: This study included 271 thyroid lobes...

Correction: Automated tumor stroma ratio assessment in colorectal cancer using hybrid deep learning approach

Integrative multiomics-histopathology analysis for breast cancer classification

Abstract Histopathologic evaluation of biopsy slides is a critical step in diagnosing and subtyping breast cancers. However, the connections between histology and multi-omics status have never been systematically explored or interpreted. We...

A deep learning approach to predict blood-brain barrier permeability

The blood–brain barrier plays a crucial role in regulating the passage of 98% of the compounds that enter the central nervous system (CNS). Compounds with high permeability must be identified to enable the synthesis of brain medications for...

Deep Learning for Identifying Metastatic Breast Cancer

The International Symposium on Biomedical Imaging (ISBI) held a grand challenge to evaluate computational systems for the automated detection of metastatic breast cancer in whole slide images of sentinel lymph node biopsies. Our team won bo...

Machine and deep learning methods for radiomics

Radiomics is an emerging area in quantitative image analysis that aims to relate large-scale extracted imaging information to clinical and biological endpoints. The development of quantitative imaging methods along with machine learning has...

Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images

Abstract Programmed death-ligand 1 (PD-L1) expression is currently used in the clinic to assess eligibility for immune-checkpoint inhibitors via the tumor proportion score (TPS), but its efficacy is limited by high interobserver variability...

A deep learning model for the localization and extraction of brain tumors from MR images using YOLOv7 and grab cut algorithm

IntroductionBrain tumors are a common disease that affects millions of people worldwide. Considering the severity of brain tumors (BT), it is important to diagnose the disease in its early stages. With advancements in the diagnostic process...

A paradigm shift toward explainable and federated intelligence for brain tumor MRI analysis.