Academic Articles & Research Papers

Electronic symptom monitoring of patient-reported outcomes among patients with hepatocellular carcinoma during immunotherapy (PRIME-HCC): protocol for a randomised controlled trial

Introduction Electronic patient-reported outcome (ePROs)-based symptom monitoring benefits health-related quality of life (HRQoL) in various cancers. However, despite the high disease and economic burden of hepatocellular carcinoma (HCC) an...

Conceptualisation and design of a protocol for a novel social drivers and primary care screening tool in paediatric orthopaedics: a quality improvement initiative

Introduction Paediatric patients with elevated healthcare needs have limited access to care, contributing to insufficient preventive services. Social drivers of health (SDOH), such as inadequate nutrition and poor community support, contrib...

Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol

Introduction People with cystic fibrosis (CF) are living longer and healthier lives with a growing number considering and pursuing parenthood. The decision of whether to become a parent is complex for people with CF, and CF is a major facto...

Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an observational study

Objectives To evaluate the impact of ALgorithm for the MANAgement of CHildhood illness (‘ALMANACH’), a digital clinical decision support system (CDSS) based on the Integrated Management of Childhood Illness, on health and quality of care ou...

Exploring health literacy pertaining to general wellbeing and chronic disease management among population registered within Primary Healthcare System: A Study protocol.

BackgroundEvidence suggests that high level of health literacy among patients is associated with high levels of accessibility to healthcare, better understanding consent-to-treat forms, increased compliance to treatment (particularly in tak...

Why do healthcare professionals fail to escalate as per the early warning system (EWS) protocol? A qualitative evidence synthesis of the barriers and facilitators of escalation

Abstract Background Early warning systems (EWSs) are used to assist clinical judgment in the detection of acute deterioration to avoid or reduce adverse events including unanticipated cardiopulmonary arrest, admission to the intensive care ...

Molecular Characterization of Cryptosporidium Species in Children with Diarrhea in North West of Iran

Cryptosporidium is one of the most common causes of childhood diarrhea in developing countries. The aim of this randomized pilot study was to detect and characterize infective species and determine the genotypes of Cryptosporidium parasites...

Lipidomic Analysis of Caenorhabditis elegans Embryos

Metabolomic is an emerging field of system biology. Lipidomic, a branch of metabolomic, aims to characterize lipophilic metabolites in biological systems. Caenorhabditis elegans (C. elegans) is a genetically tractable and versatile animal m...

Laboratory Protocols in Medical Biotechnology I

Chromosomal Instability in Various Generations of Human Mesenchymal Stem Cells Following the Therapeutic Radiation

Background. Radiotherapy is a crucial treatment for most malignancies. However, it can cause several side effects, including the development of secondary malignancies due to radiation-induced genomic instability (RIGI). The aim of this stud...

Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males

BackgroundColorectal cancer (CRC) is the third most common type of cancer and leading cause of death worldwide. Major risk factors involved in the development of CRC are increased dietary sources, genetics, and increasing age. Purpose of th...

How Does the Diversity of Divers Affect the Design of Citizen Science Projects?

Divers have widely participated in citizen science (CS) projects and are one of the main groups of marine citizen scientists. However, there is little knowledge about profiles of, and incentives for potential divers to join CS projects. To ...

Meeting unmet needs following minor stroke: the SUN randomised controlled trial protocol

Abstract Background Whilst there are comprehensive guidelines for the rehabilitation of people with severe impairments from stroke, there has been less attention on the health and rehabilitation needs of people with minor stroke. Our study ...

Applying Sümer’s model of military turnover on junior officers for a private security firm in Windhoek, Namibia

The concern of staff turnover affects all organisations whether public or private, and security firms are no exception. This study set out to investigate the influences behind the exodus of junior officers from a private security firm. It f...

Rethinking avian influenza control: a systems-oriented One Health perspective for family poultry

Early detection and control of high- and low-pathogenicity avian influenza (HPAI, LPAI) in family poultry flocks remain challenging in settings where mortality from enzootic diseases such as Newcastle disease (ND) and infectious bursal dise...

Effect of chemical treatment on the mechanical and thermal performance of flax fiber reinforced aluminium 6082 laminate: a machine learning-enhanced investigation

Abstract This work examined the role of alkaline and epoxy-based surface chemical treatments on the mechanical and thermal properties of flax fiber reinforced Aluminum Alloy 6082 hybrid Fiber Metal Laminates (FMLs), integrated with machine ...

A Comparison of Energy Consumption and Quality of Solutions in Evolutionary Algorithms

Evolutionary algorithms are extensively used to solve optimisation problems. However, it is important to consider and reduce their energy consumption, bearing in mind that programming languages also significantly affect energy efficiency. T...

sEMG-controlled forearm bracelet and serious game-based rehabilitation for training manual dexterity in people with multiple sclerosis: a randomised controlled trial

Abstract Background Muscle strength and dexterity impairments are common among patients with multiple sclerosis (MS) producing limitations in activities of daily living related to the upper limb (UL). This study aimed to evaluate the effect...

The Development of a Secure Internet Protocol (IP) Network Based on Asterisk Private Branch Exchange (PBX)

The research problem described in this article is related to the security of an IP network that is set up between two cities using hosting. The network is used for transmitting telephone traffic between servers located in Germany and the Ne...

In Vitro Propagation of the Endangered <i>Kosteletzkya pentacarpos</i> (L.) Ledeb: Conservation Applications and Horticultural Prospects

Employing rare or threatened species in ornamental horticulture offers a dual benefit by promoting climate adaptation and enhancing species conservation. Kosteletzkya pentacarpos, an endangered halophytic species, holds potential for introd...